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The first complete papillomavirus genome characterized from a marsupial host: a novel isolate from Bettongia penicillata

Bennett, M.D., Reiss, A., Stevens, H., Heylen, E., Van Ranst, M., Wayne, A., Slaven, M., Mills, J.N., Warren, K.S.ORCID: 0000-0002-9328-2013, O'Hara, A.J. and Nicholls, P.K.ORCID: 0000-0001-7071-3055 (2010) The first complete papillomavirus genome characterized from a marsupial host: a novel isolate from Bettongia penicillata. Journal of Virology, 84 (10). pp. 5448-5453.

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Link to Published Version: http://dx.doi.org/10.1128/JVI.02635-09
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Abstract

The first fully sequenced papillomavirus (PV) of marsupials, tentatively named Bettongia penicillata papillomavirus type 1 (BpPV1), was detected in papillomas from a woylie (Bettongia penicillata ogilbyi). The circular, double-stranded DNA genome contains 7,737 bp and encodes 7 open reading frames (ORFs), E6, E7, E1, E2, E4, L2, and L1, in typical PV conformation. BpPV1 is a close-to-root PV with L1 and L2 ORFs most similar to European hedgehog PV and bandicoot papillomatosis carcinomatosis virus types 1 and 2 (BPCV1 and -2). It appears that the BPCVs arose by recombination between an ancient PV and an ancient polyomavirus more than 10 million years ago.

Item Type: Journal Article
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Publisher: American Society for Microbiology
Copyright: 2010, American Society for Microbiology
URI: http://researchrepository.murdoch.edu.au/id/eprint/1812
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