Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue

Chua‐anusorn, W., St Pierre, T.G., Macey, D.J. and Webb, J. (1998) Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue. Inorganica Chimica Acta, 267 (1). pp. 7-10.

Abstract

Mössbauer spectroscopy was used to monitor, over a period of three days, the form of iron in iron-loaded spleen tissue following splenectomy from a patient with β-thalassemia. The tissue was stored at room temperature for a three day period in order to allow degradation and autolytic processes to take place. The majority of the iron in the fresh spleen tissue was found to be in the form of inorganic polynuclear iron (III) oxyhydroxide clusters associated with ferritin and hemosiderin. After three days, some of the iron had been reduced to high-spin iron (II).

Item Type:	Journal Article
Murdoch Affiliation(s):	School of Biological Sciences and Biotechnology
Publisher:	Elsevier
Copyright:	© 1998 Elsevier Science
URI:	http://researchrepository.murdoch.edu.au/id/eprint/1788

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