Synthesis of new semi-rigid chelating agents for samarium-153

Loussouarn, A., Ouadi, A., Morandeau, L., Remaud, P., Giles, R., Gestin, J-F and Webb, J. (2003) Synthesis of new semi-rigid chelating agents for samarium-153. Tetrahedron Letters, 44 (17). pp. 3539-3541.

Abstract

This study describes a simple, efficient synthesis pathway from trans-1,2-diaminocyclohexane that provides access to a new class of semi-rigid polyamine, polycarboxylic, and polyphosphonic ligands. The key steps in synthesis were the functionalisation (with an appropriate branching group) of a bisphosphonate diaminocyclohexane derivative and the introduction of methanephosphonic functions by a rarely used method.

Item Type:	Journal Article
Murdoch Affiliation:	School of Biological Sciences and Biotechnology
Publisher:	Elsevier BV
Copyright:	© 2003 Published by Elsevier Science Ltd
URI:	http://researchrepository.murdoch.edu.au/id/eprint/16952

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