Successful treatment of macrophage activation syndrome complicating adult Still disease with anakinra
Loh, N.K., Lucas, M., Fernandez, S. and Prentice, D. (2012) Successful treatment of macrophage activation syndrome complicating adult Still disease with anakinra. Internal Medicine Journal, 42 (12). pp. 1358-1362.
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Abstract
A previously healthy 20-year-old man presented with adult Still disease (ASD). He developed life-threatening macrophage activation syndrome (MAS), which was refractory to standard immunosuppression but responded dramatically to the IL-1 receptor antagonist anakinra. Subsequent immunological investigations included assessment of the perforin expression of natural killer (NK) cells and CD8+ T cells, which confirmed MAS.
Item Type: | Journal Article |
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Murdoch Affiliation(s): | Centre for Clinical Immunology and Biomedical Statistics |
Publisher: | Blackwell Publishing |
Copyright: | © 2012 The Authors |
URI: | http://researchrepository.murdoch.edu.au/id/eprint/12562 |
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