Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Further evaluation of a novel polymeric antimicrobial for the control of porcine postweaning colibacillosis

Hampson, D.J.ORCID: 0000-0002-7729-0427 (2003) Further evaluation of a novel polymeric antimicrobial for the control of porcine postweaning colibacillosis. Journal of Swine Health and Production, 11 (5). pp. 223-228.

[img]
Preview
PDF - Published Version
Download (158kB) | Preview
Free to read: http://www.aasv.org/shap/issues/v11n5/v11n5p223.ht...
*No subscription required

Abstract

Objectives: To evaluate a new polymeric antimicrobial for the control of porcine postweaning colibacillosis (PWC).

Materials and methods: In an experimental infection study, three groups of 12 weaner pigs received either Chemeq polymeric antimicrobial in the food, a therapeutic dosage of apramycin orally, or no treatment. Three days after weaning, the pigs were challenged orally with cultures of [beta]-hemolytic Escherichia coli O8:K87:K88, then monitored daily and euthanized 11 days after weaning. In a field trial, 148 weaned pigs in a commercial swine herd were divided into five groups, receiving polymeric antimicrobial either in their water or food, apramycin in their water, a commercial E coli PWC bacterin, or no treatment. Postweaning performance was monitored.

Results: In the infection study, pigs receiving polymeric antimicrobial had less diarrhea than the apramycin-treated group (P <.01) but not the untreated control group, and had fewer hemolytic E coli in their large intestines than the control pigs (P <.05). In the field trial, pigs receiving polymeric antimicrobial had less diarrhea than pigs in the other groups (P <.05), and fewer were removed from the study because of severe PWC (P <.05).

Discussion: Antimicrobial resistance is increasing amongst PWC strains of E coli, and new antimicrobials and strategies are needed to maintain postweaning health and production. Chemeq polymeric antimicrobial reduced diarrhea after weaning, and was a useful adjunct to the control of PWC.

Implications: Chemeq polymeric antimicrobial has therapeutic advantage in the treatment and control of PWC.

Item Type: Journal Article
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Publisher: American Association of Swine Veterinarians
URI: http://researchrepository.murdoch.edu.au/id/eprint/11827
Item Control Page Item Control Page

Downloads

Downloads per month over past year