Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Studies on BCG immunotherapy in mice infected with Mesocestoides corti

White, T.R., Thompson, R.C.A. and Penhale, W.J. (1988) Studies on BCG immunotherapy in mice infected with Mesocestoides corti. International Journal for Parasitology, 18 (3). pp. 389-393.

Link to Published Version:
*Subscription may be required


Two doses (4 x 107) of Bacillus Calmette-Guerin (BCG) induced therapeutic resistance to Mesocestoides corti in mice when given 14 and 28 days post-infection. This was not elicited by a single dose of BCG given 14 days after infection. BCG-induced resistance was not affected by the immunosuppressive agents carrageenan, cyclophosphamide and methyl prednisolone. Resistance was transferred by spleen cells exposed in vivo to both parasite antigen and BCG but not BCG alone. Resistance appeared to be specific for M. corti as spleen cells sensitized to Taenia crassiceps failed to confer resistance M. corti in the presence of BCG.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary Studies
Publisher: Elsevier BV
Item Control Page Item Control Page