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Number of items: 183.

2014

Strautins, K., Tschochner, M., James, I., Choo, L., Dunn, D., Pedrini, M., Kermode, A., Carroll, W. and Nolan, D. (2014) Combining HLA-DR risk alleles and anti-Epstein-Barr virus antibody profiles to stratify multiple sclerosis risks. Multiple Sclerosis Journal, 20 (3). pp. 286-294.

2013

Herrmann, S., McKinnon, E., Hyland, N.B., Lalanne, C., Mallal, S., Nolan, D., Chassany, O. and Duracinsky, M. (2013) HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection. Health and Quality of Life Outcomes, 11 (1).

Qiu, W., Pham, K., James, I., Nolan, D., Castley, A., Christiansen, F.T., Czarniak, P., Luo, Y., Wu, J., Garlepp, M., Wilton, S., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2013) The influence of non-HLA gene polymorphisms and interactions on disease risk in a Western Australian multiple sclerosis cohort. Journal of Neuroimmunology, 261 (1-2). pp. 92-97.

2012

Nolan, D., Mallal, S. and Reiss, P. (2012) Complications resulting from antiretroviral therapy for HIV infection. In: Volberding, P., Greene, W., Lange, J.M.A., Gallant, J.E. and Sewankambo, N., (eds.) Sande's HIV/AIDS Medicine: Medical Management of AIDS 2013. Elsevier Inc., pp. 177-191.

Nolan, D., Castley, A., Tschochner, M., James, I., Qiu, W., Sayer, D., Christiansen, F.T., Witt, C., Mastaglia, F., Carroll, W. and Kermode, A. (2012) Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk. Neurology, 79 (6). pp. 538-546.

Achhra, A.C., Amin, J., Hoy, J., Tanuma, J., Sirisanthana, T., Nolan, D., Merati, T. and Giles, M. (2012) Differences in lipid measurements by antiretroviral regimen exposure in cohorts from Asia and Australia. AIDS Research and Treatment, 2012 . pp. 1-9.

Lee, M.H., Stocker, S.L., Anderson, J., Phillips, E.J., Nolan, D., Williams, K.M., Graham, G.G., Sullivan, J.R. and Day, R.O. (2012) Initiating allopurinol therapy: do we need to know the patient's human leucocyte antigen status? Internal Medicine Journal, 42 (4). pp. 411-416.

Herrmann, S., Wardrop, J., John, M., Gaudieri, S., Lucas, M., Mallal, S. and Nolan, D. (2012) The impact of visa status and Medicare eligibility on people diagnosed with HIV in Western Australia: a qualitative report. Sexual Health, 9 (5). p. 407.

2011

Herrmann, S., John, M., Wardrop, J. and Nolan, D. (2011) Antiretroviral issues in temporary visa holders in Western Australia: A qualitative report on access, attitude and adherence. In: 23rd Annual Australasian Society for HIV Medicine Conference, 26 - 28 September, Canberra, Australia.

Pfafferott, K., Gaudieri, S., Ulsenheimer, A., James, I., Heeg, M., Nolan, D., John, M., Rauch, A., Mallal, S., Lucas, A.D., Klenerman, P., Diepolder, H.M. and Lucas, M. (2011) Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity. PLoS ONE, 6 (2). e16797.

Herrmann, S., John, M., Wardrop, J. and Nolan, D. (2011) Experiences of people on temporary visas who are diagnosed with HIV in Western Australia. In: 23rd Annual Australasian Society for HIV Medicine Conference, 26 - 28 September, Canberra, Australia.

Hertz, T., Nolan, D., James, I., John, M., Gaudieri, S., Phillips, E., Huang, J., Riadi, G., Mallal, S. and Jojic, N. (2011) HLA class I binding and its relationship with evolutionary conservation in human proteins and viral proteomes. In: Keystone HIV Evolution Genomics & Pathogenesis, 20 - 25 March 2011, Whistler, British Columbia, Canada.

Herrmann, S., Lucas, M., John, M. and Nolan, D. (2011) Implementing medication adherence interventions into HIV clinical care: Implications for current research and other blood borne viruses. In: WA SiREN Research Symposium - Found or Lost in Translation, 6 May, Perth, Western Australia.

Hertz, T., Nolan, D., James, I., John, M., Gaudieri, S., Phillips, E.J., Huang, J.C., Riadi, G., Mallal, S. and Jojic, N. (2011) Mapping the Landscape of Host-Pathogen Coevolution: HLA Class I Binding and Its Relationship with Evolutionary Conservation in Human and Viral Proteins. Journal of Virology, 85 (3). pp. 1310-1321.

Law, M.G., Woolley, I., Templeton, D.J., Roth, N., Chuah, J., Mulhall, B., Canavan, P., McManus, H., Cooper, D.A., Petoumenos, K. and Nolan, D. (2011) Trends in detectable viral load by calendar year in the Australian HIV observational database. Journal of the International AIDS Society, 14 (1). pp. 10-16.

2010

Martin, A., Amin, J., Cooper, D.A., Carr, A., Kelleher, A.D., Bloch, M., Baker, D., Woolley, I., Emery, S. and Nolan, D. (2010) Abacavir does not affect circulating levels of inflammatory or coagulopathic biomarkers in suppressed HIV: A randomized clinical trial. AIDS, 24 (17). pp. 2657-2663.

John, M., Heckerman, D., James, I., Park, L.P., Carlson, J.M., Chopra, A., Gaudieri, S., Nolan, D., Haas, D.W., Riddler, S.A., Haubrich, R. and Mallal, S. (2010) Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. The Journal of Immunology, 184 (8). pp. 4368-4377.

McGettigan, B.D., McKinnon, E., Mallal, S., French, M., Hammond, E., Nolan, D. and Phillips, E.J. (2010) Association between low 25(OH) vitamin D levels, antiretroviral therapy and metabolic profile in a cohort of treated ahd therapy naive HIV positive patients in Western Australia. In: 22nd Annual Conference of the Australasian Society for HIV Medicine, 20 - 22 October 2010, Sydney, Australia.

Iwabu, Y., Kinomoto, M., Tatsumi, M., Fujita, H., Shimura, M., Tanaka, Y., Ishizaka, Y., Nolan, D., Mallal, S., Sata, T. and Tokunaga, K. (2010) Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes. Journal of Biological Chemistry, 285 (46). pp. 35350-35358.

Falster, K., Wand, H., Donovan, B., Anderson, J., Nolan, D., Watson, K., Watson, J. and Law, M.G (2010) Hospitalizations in a cohort of HIV patients in Australia, 1999–2007. AIDS, 24 (9). pp. 1329-1339.

Hammond, E.L., McKinnon, E. and Nolan, D. (2010) Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences. Clinical Infectious Diseases, 51 (5). pp. 591-599.

Friis-Møller, N., Thiébaut, R., Reiss, P., Weber, R., Monforte, A.D., De Wit, S., El-Sadr, W., Fontas, E., Worm, S., Kirk, O., Phillips, A., Sabin, C.A., Lundgren, J.D., Law, M.G., Mallal, S. and Nolan, D. (2010) Predicting the risk of cardiovascular disease in HIV-infected patients: The Data collection on Adverse Effects of Anti-HIV Drugs Study. European Journal of Cardiovascular Prevention & Rehabilitation, 17 (5). pp. 491-501.

Herrmann, S.E., McKinnon, E.J., Williams, L.J., John, M., Mallal, S., Lucas, M. and Nolan, D.A. (2010) Use of alcohol, nicotine and other drugs in the Western Australian HIV Cohort study. Sexual Health, 9 (2). pp. 199-201.

Herrmann, S., Williams, L., McKinnon, E. and Nolan, D. (2010) Vulnerable populations: Substance use in the WA HIV Cohort Study. In: 17th Western Australian Drug and Alcohol Symposium, 30 August - 1 September, Fremantle, Western Australia.

2009

Falster, K., Choi, J.Y., Donovan, B., Duncombe, C., Mulhall, B., Sowden, D., Zhou, J., Law, M.G., Mallal, S. and Nolan, D. (2009) AIDS-related and non-AIDS-related mortality in the Asia-Pacific region in the era of combination antiretroviral treatment. AIDS, 23 (17). pp. 2323-2336.

McKinnon, E., Morahan, G., Nolan, D. and James, I. (2009) Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 92-100.

Gaudieri, S., Rauch, A., James, I., Pfafferott, K., Baker, R., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G., Mollinson, L., Mallal, S., Furrer, H., Günthard, H., Hirschel, B., Klenerman, P., Nolan, D., John, M. and Lucas, M. (2009) Co-localisation of hepatitis C virus drug-resistant mutations and immune-driven adaptations: Relevance to therapy outcome. In: 19th Annual Combined Biological Sciences Meeting 2009, 28 August 2009, Perth, Western Australia.

Gaudieri, S., Rauch, A., James, I., Pfafferott, K., Cheng, W., McCaughan, G., Jeffrey, G., Mollison, L., Furrer, H., Günthard, H., Hirschel, B., Klenerman, P., Mallal, S., Nolan, D., John, M. and Lucas, M. (2009) Divergent adaptation of Hepatitis C virus genotypes to HLA-restricted immune pressure: relevance to HCV infection and vaccine design. In: 16th International Symposium on Hepatitis C Virus & Related Viruses, 3 - 7 October 2009, Nice, France.

Rauch, A., James, I., Pfafferott, K., Nolan, D., Klenerman, P., Cheng, W., Mollison, L., McCaughan, G., Shackel, N., Jeffrey, G.P., Baker, R., Freitas, E., Humphreys, I., Furrer, H., Günthard, H.F., Hirschel, B., Mallal, S., John, M., Lucas, M., Barnes, E. and Gaudieri, S. (2009) Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure. Hepatology, 50 (4). pp. 1017-1029.

Pfafferott, K., Gaudieri, S., Ulsenheimer, A., John, M., James, I., Heeg, M., Nolan, D., Rauch, A., Lucas, A., Klenerman, P., Diepolder, H.M. and Lucas, M. (2009) Divergent pattern of viral evolution and escape dynamics in acute and early HCV and HIV infection. In: Australasian Virology Group Meeting, 13 - 17 December 2009, Mantra Erskine Resort, Lorne, VIC.

Nolan, D. and Mallal, S. (2009) EBV and MS: Lessons from hepatitis and HIV. In: 10th Biennial Scientific Conferene on "Progress on MS Research" - MSRA Conference 2009, 15 - 17 October 2009, Sydney, Australia.

Nolan, D. (2009) HLA-B*5701 screening prior to abacavir prescription: Clinical and laboratory aspects. Critical Reviews in Clinical Laboratory Sciences, 46 (3). pp. 153-165.

Herrmann, S., Duracinsky, M., Lalanne, C., Acquadro, C., Mallal, S. and Nolan, D. (2009) Health-related quality of life in the WA HIV Cohort: 2008. In: 21st Annual Conference of the Australasian Society for HIV Medicine (ASHM), 9 - 11 September, Brisbane, Australia.

Gaudieri, S., Rauch, A., Pfafferott, K., Barnes, E., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G.P., Mollison, L., Baker, R., Furrer, H., Günthard, H.F., Freitas, E., Humphreys, I., Klenerman, P., Mallal, S., James, I., Roberts, S., Nolan, D. and Lucas, M. (2009) Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy. Hepatology, 49 (4). pp. 1069-1082.

Egger, S., Petoumenos, K., Kamarulzaman, A., Hoy, J., Sungkanuparph, S., Chuah, J., Falster, K., Zhou, J., Law, M.G., Mallal, S. and Nolan, D. (2009) Long-term patterns in CD4 response are determined by an interaction between baseline CD4 cell count, viral load, and time: The Asia Pacific HIV Observational Database (APHOD). JAIDS Journal of Acquired Immune Deficiency Syndromes, 50 (5). pp. 513-520.

Carey, D., Baker, D., Petoumenos, K., Chuah, J., Rogers, G.D., Watson, J., Cooper, D.A., Emery, S., Carr, A. and Nolan, D. (2009) Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-up. HIV Medicine, 10 (3). pp. 163-172.

Herrmann, S., Williams, L., McKinnon, E. and Nolan, D. (2009) Substance use in the WA HIV Cohort: 2002-2008. In: 21st Annual Conference of the Australasian Society for HIV Medicine (ASHM), 9 - 11 September, Brisbane, Australia.

Netto, J., Keane, N., Mullaney, I., Nolan, D., Mallal, S. and Trengove, R. (2009) The alternate metabolism of abacavir and its role in immune-mediated hypersensitivity reactions in HIV infected individuals. In: 57th ASMS Conference on Mass Spectrometry and Allied Topics, 31 May - 4 June 2009, Philadelphia, USA.

Lee, M.H., Anderson, J., Stocker, S.L., Williams, K.M., Graham, G.G., Phillips, E.J., Nolan, D. and Day, R.O. (2009) A tale of two brothers: A familial study of risk factors to allopurinol-induced Stevens-Johnson Syndrome. In: Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Conference 2009, 29 November - 2 December 2009, Sydney Convention Centre, Sydney.

2008

Phillips, E., Nolan, D. and Mallal, S. (2008) The Authors reply - Response to Vandekerckhove et al & Abel et al. New England Journal of Medicine, 358 (23). pp. 2515-2516.

Almeida, C.M., Martin, A.M., Nolan, D., Lucas, A., Cameron, P.U., James, I., Phillips, E. and Mallal, S. (2008) Cytokine profiling in abacavir hypersensitivity patients. Antiviral Therapy, 13 (2). pp. 281-288.

Duracinsky, M., Herrmann, S., Acquadro, C., Berzins, B., Le Coeur, S., Hyland, N., Fournier, I., McKinnon, E., Nolan, D., Mallal, S. and Chassany, O. (2008) Development of a new health-related quality of life questionnaire specific to HIV/AIDS: an international and cross cultural initiative. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Mallon, P.W.G., Sedwell, R., Rogers, G., Nolan, D., Unemori, P., Hoy, J., Samaras, K., Kelleher, A., Emery, S., Cooper, D.A. and Carr, A. (2008) Effect of rosiglitazone on peroxisome proliferator‐activated receptor γ gene expression in human adipose tissue is limited by antiretroviral drug–induced mitochondrial dysfunction. The Journal of Infectious Diseases, 198 (12). pp. 1794-1803.

Hammond, E.L., Martin, A., Nolan, D., Metcalf, C. and Mallal, S. (2008) Eruptive haemangioma associated with HIV therapy and mitochondrial pathology. Pathology, 40 (4). pp. 425-429.

Phillips, E., Nolan, D., Thorborn, D., Schaefer, M., Laird, R., Rauch, A., Rachlis, A., Shear, N., Knowles, S., Hughes, A., Montaner, J., James, I. and Mallal, S. (2008) Genetic factors predicting abacavir hypersensitivity and tolerance in HLA-B*5701 positive individuals. In: 3rd International Drug Hypersensitivity Conference, 11 - 13 April 2008, Paris, France.

Nolan, D., Thorborn, D., Shaefer, M., Laird, R., Montaner, M., Hughes, A., James, I., Mallal, S. and Phillips, E. (2008) Genetic factors predicting abacavir hypersensitivty and tolerance in HLA-B*5701 positive individuals: Combined analysis from PREDICT-1, SHAPE and a multinational study. In: 15th Conference on Retroviruses and Opportunistic Infections (CROI), 3 - 6 February 2008, Boston, U.S.A.

Rauch, A., Thurnheer, C., Fux, C., Nolan, D. and Mallal, S. (2008) Genetic testing and a structured clinical assessment reveal overdiagnosis of abacavir hypersensitivity reactions in the Swiss HIV Cohort study. In: 12th International Workshop on HIV Observational Databases, 27 - 30 March 2008, Malaga, Spain.

Rauch, A., Thurnheer, C., Fux, C., Nolan, D., Cavassini, M., Chave, J-P, Opravil, M., Phillips, E., Mallal, S. and Furrer, H. (2008) Genetic testing and structured clinical assessment reveal over diagnosis of abacavir hypersensitivity reactions in the Swiss HIV Cohort Study. In: 12th International Workshop on HIV Observational Databases, 27 - 30 March 2008, Malaga, Spain.

Mallal, S., Phillips, E., Carosi, G., Molina, J-M, Workman, C., Tomazic, J., Jagel-Guedes, E., Rugina, S., Kozyrev, O., Cid, J.F., Hay, P., Nolan, D., Hughes, S., Hughes, A., Ryan, S., Fitch, N., Thorborn, D. and Benbow, A. (2008) HLA-B*5701 screening for hypersensitivity to Abacavir. The New England Journal of Medicine, 358 (6). pp. 568-579.

Rauch, A., Nolan, D., Furrer, H., McKinnon, E., John, M., Mallal, S., Gaudieri, S., Günthard, H.F., Schmid, P., Battegay, M., Hirschel, B., Telenti, A., James, I. and Swiss HIV Cohort Study, . (2008) HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy. Clinical Infectious Diseases, 46 (12). pp. 1921-1925.

Mallal, S., John, M., Gaudieri, S., Phillips, E. and Nolan, D. (2008) How might understanding of the co-evolution of HLA and viruses inform contemporary clinical issues. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Chessman, D., Kostenko, L., Lethborg, T., Purcell, A.W., Williamson, N.A., Chen, Z., Kjer-Nielsen, L., Mifsud, N.A., Tait, B.D., Holdsworth, R., Almeida, C.M., Nolan, D., Macdonald, W.A., Archbold, J.K., Kellerher, A.D., Marriott, D., Mallal, S., Bharadwaj, M., Rossjohn, J. and McCluskey, J. (2008) Human leukocyte Antigen Class I-restricted activation of CD8+ T Cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity, 28 (6). pp. 822-832.

Hammond, E., McKinnon, E., Pace, C., Mallal, S. and Nolan, D. (2008) Influence of NRTI choice and efavirenz versus lopinavir treatment options on lipoatrophy-associated adipose tissue toxicity: A longitudinal study. In: 15th Conference on Retroviruses and Opportunistic Infections (CROI), 3 - 6 February 2008, Boston, U.S.A.

Martínez, E. and Nolan, D. (2008) Long-term management of the HIV-infected patient - Tailoring highly active antiretroviral therapy to optimise therapeutic outcome. European Infectious Diseases, 2 (2). pp. 16-22.

Hammond, E.L., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. AIDS, 22 (18). pp. 2540-2543.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. In: 10th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 6 - 8 November 2008, London, England.

Rauch, A., Gaudieri, S., Evison, J., Nolan, D., Cavassini, M., Weber, R., James, I. and Furrer, H. (2008) Low current and nadir CD4+ T-cell counts are associated with higher hepatitis C virus RNA levels in the Swiss HIV cohort study. Antiviral Therapy, 13 (3). pp. 455-60.

Gaudieri, S., Rauch, A., Mallal, S., Roberts, S., Nolan, D. and Lucas, M. (2008) Overlapping selection of hepatitis C virus drug-resistant mutations and immune-driven adaptations. In: Australian Centre for HIV and Hepatitis Virology Research (ACH2) 4th Annual Workshop, 4 - 6 June 2008, Novotel Barossa Valley Resort, South Australia.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Pathogenesis of lipoatrophy: Analysis of tissue and plasma. In: 10th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 6 - 8 November 2008, London, England.

Rauch, A., Nolan, D., Thurnheer, C., Fux, C.A., Cavassini, M., Chave, J-P, Opravil, M., Phillips, E., Mallal, S. and Furrer, H. (2008) Refining abacavir hypersensitivity diagnoses using a structured clinical assessment and genetic testing in the Swiss HIV Cohort Study. Antiviral Therapy, 13 (8). pp. 1019-1028.

Lo, G., Herrmann, S., Cheng, W., Kontorinis, N., Phillips, E., Nolan, D. and Lucas, M. (2008) Screening for hepatocellular carcinoma (HCC) in hepatitis/HIV co-infection using ultrasound imaging and alfa-feto protein levels. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Herrmann, S., McKinnon, E., John, M., Nolan, D., Martinez, O.P., Phillips, E. and Mallal, S. (2008) Side effects, dosing schedules, pill burden and perceived stress: Interaction and influence on medication adherence. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

2007

Hammond, E. and Nolan, D. (2007) Adipose tissue inflammation and altered adipokine and cytokine production in antiretroviral therapy-associated lipodystrophy (Review). Current Opinion in HIV and AIDS, 2 (4). pp. 274-281.

Hammond, E., Mamotte, C., Nolan, D. and Mallal, S. (2007) HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay. Tissue Antigens, 70 (1). pp. 58-61.

Nolan, D. (2007) The view from Sydney: 9th International Lipodystrophy Workshop. Nutrition and Metabolic Disorders in HIV Infection, 6 (3). pp. 1161-1164.

Martin, A., Almeida, C.M., Cameron, P.U., Purcell, Anthony W, Nolan, D., James, I., McCluskey, J., Phillips, E.J., Landay, Alan and Mallal, S. (2007) Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS, 21 (10). pp. 1233-1244.

Lucas, A., Nolan, D. and Mallal, S. (2007) HLA-B*5701 screening for susceptibility to abacavir hypersensitivity. Journal of Antimicrobial Chemotherapy, 59 (4). pp. 591-593.

Nolan, D., Almeida, C. and Phillips, E.J. (2007) Abacavir hypersensitivity. In: Pichler, W., (ed.) Drug Hypersensitivity. S. Karger AG, Basel, Switzerland, pp. 116-125.

Nolan, D., Almeida, C., Phillips, E. and Mallal, S. (2007) Abacavir hypersensitivity. In: Pichler, W.J., (ed.) Drug Hypersensitivity. S. Karger AG, Basel, Switzerland, pp. 95-104.

McCluskey, J., Chessman, D., Lethborg, T., Kostenko, L., Purcell, A.W., Kjer-Nielsen, L., Mifsud, N.A., Tait, B.D., Holdsworth, R., Almeida, C., Nolan, D., Mallal, S., Bharadwaj, M. and Rossjohn, J. (2007) Abacavir hypersensitivity in HLA-B57-positive individuals with HIV infection is dependent upon the conventional MHC-I Ag presentation pathway. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2007) Erratum: Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation (Journal of Virology (2006) 80, 18, (9259-9269)). Journal of Virology, 81 (16). pp. 8843-8845.

Hammond, E., Almeida, C.M., Mamotte, C., Nolan, D., Phillips, E.J., Schollaardt, T.A., Gill, M.J., Angel, J.B., Neurath, D., Li, J., Giulivi, T., McIntyre, C., Koultchitski, G., Wong, B., Reis, M., Rachlis, A., Cole, D., Chew, C.B., Neifer, S., Lalonde, R., Roger, M., Jeanneau, A. and Mallal, S. (2007) External quality assessment of HLA-B*5701 reporting: an international multicentre survey. Antiviral Therapy, 12 (7). pp. 1027-1032.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Laird, R., Montaner, J., Shear, N., Lucas, A. and Mallal, S. (2007) Genetic characterization of patch test negative patients reporting symptoms after initiation after abacavir. In: 8th International Workshop on Clinical Pharmacology of HIV Therapy, 16 - 18 April 2007, Budapest, Hungary.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Knowles, S., Shear, N., Cavassini, M., Harrigan, R., Montaner, J., Keane, N., Laird, R., Lucas, A. and Mallal, S. (2007) Genetic characterization of patients with MHC class I mediated abacavir hypersensitivity reaction. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Patterson, A., Sutton, K., Laird, R., Choo, L., Denholm, S., Chopra, A., Lucas, A., Nolan, D., John, M., Gaudieri, S. and Mallal, S. (2007) HLA genotyping for Population-based pathogen and disease associations research. In: 31st Annual Scientific Meeting of the Australasian and South East Asian Tissue Typing Association (ASEATTA) 2007, 14 - 16 November 2007, Fremantle, WA.

Hammond, E., Almeida, C., Mamotte, C., Nolan, D., Phillips, E., Schollaardt, T., Gill, M.J., Angel, J.B., Neurath, D., Li, J., Giulivi, T., McIntyre, C., Koultchitski, G., Wong, B., Reis, M., Rachlis, A., Cole, D.E., Chew, C.B., Neifer, S. and Mallal, S. (2007) Multi-centre evaluation of HLA-B*5701 allele detection by SSP-PCR typing: a quality assurance initiative. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Mallal, S., Phillips, E., Carosi, G., Molina, J-M, Workman, C., Tomazic, J., Jagel-Guedes, E., Rugina, S., Kozyrev, O., Flores, C.J., Hay, P., Nolan, D., Hughes, S., Hughes, A., Thorborn, D. and Benbow, A. (2007) PREDICT-1: a novel randomised prospective study to determine the clinical utility of HLA-B*5701 screening to reduce abacavir hypersensitivity in HIV-1 infected subjects. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

John, M., Heckerman, D., Park, L., Gaudieri, S., James, I., Nolan, D., Chopra, A., Riddler, S., Haubrich, R. and Mallal, S. (2007) Strong genome-wide HLA associated selection in HIV-1. In: 31st Annual Scientific Meeting of the Australasian and South East Asian Tissue Typing Association (ASEATTA) 2007, 14 - 16 November 2007, Fremantle, WA.

Keane, N., Lucas, A., Netto, J., Almeida, C., Martin, A., Marriott, D., Kelleher, A., Phillips, E., Nolan, D. and Mallal, S. (2007) Use of the ELISpot assay to detect abacavir- and nevirapine-induced IFN-g responses in PBMC from HIV-infected patients with abacavir or nevirapine hypersensitivity reactions. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

2006

Martin, A., Nolan, D., Almeida, C., Rauch, A. and Mallal, S. (2006) Predicting and diagnosing abacavir and nevirapine drug hypersensitivity: from bedside to bench and back again. Pharmacogenomics, 7 (1). pp. 15-23.

Martins, I.J., Hone, E., Foster, J.K., S, S.I., Gnjec, A., Fuller, S.J., Nolan, D., Gandy, S.E. and Martins, R.N. (2006) Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Molecular Psychiatry, 11 (8). pp. 721-736.

Hammond, E., Nolan, D., McKinnon, E., Pace, C. and Mallal, S. (2006) Assessing the risk of adipose tissue mitochondrial toxicity in HIV-infected individuals on contemporary NRTI regimens. In: 8th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 23 - 26 September 2006, San Fransisco, U.S.A.

Nolan, D., Phillips, E. and Mallal, S. (2006) Efavirenz and CYP2B6 polymorphism: Implications for drug toxicity and resistance. Clinical Infectious Diseases, 42 (3). pp. 408-410.

Nolan, D., Gaudieri, S. and Mallal, S. (2006) Host genetics and viral infections: Immunology taught by viruses, virology taught by the immune system. Current Opinion in Immunology, 18 (4). pp. 413-421.

Pace, C., Nolan, D. and Mallal, S. (2006) Investigation of deoxythymidylate kinase genetic variation and its influence on haematological response to zidovudine treatment. In: 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20 - 22 April 2006, Lisbon, Portugal.

Almeida, C., Mamotte, C., Nolan, D., Martin, A., Hammond, E. and Mallal, S. (2006) Investigation of the sensitivity and specificity of the HLA-B*5701 genotyping assay. In: Pharmacogenetics Meeting in Colds Spring Harbour, 10 - 15 November 2006, New York, U.S.A.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Knowles, S., Shear, N., Harris, N., Montaner, J.S.G. and Mallal, S. (2006) Pharmacogenetics and clinical characteristics of patch test confirmed patients with Abacavir hypersensitivity. In: 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20 - 22 April 2006, Lisbon, Portugal.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2006) Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation. Journal of Virology, 80 (18). pp. 9259-9269.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2006) Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study. Clinical Infectious Diseases, 43 (1). pp. 99-102.

Cherry, C.L., Nolan, D., James, I.R., McKinnon, E.J., Mallal, S.A., Gahan, M.E., Lal, L., McArthur, J.C. and Wesselingh, S.L. (2006) Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-Infected individuals. JAIDS Journal of Acquired Immune Deficiency Syndromes, 42 (4). pp. 435-440.

Martin, A.M., Krueger, R., Almeida, C.A., Nolan, D., Phillips, E. and Mallal, S. (2006) A sensitive and rapid alternative to HLA typing as a genetic screening test for abacavir hypersensitivity syndrome. Pharmacogenetics and Genomics, 16 (5). pp. 353-357.

2005

Martin, A., Almeida, C., Nolan, D., Cameron, P., James, I., Purcell, T., McCluskey, J., Phillips, E. and Mallal, S. (2005) Abacavir stimulates Hsp70 redistribution in Antigen-presenting cells of patients with hypersensitivity: Association with Type-I alcohol dehydrogenase activity. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Nolan, D., Reiss, P. and Mallal, S. (2005) Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert Opinion on Drug Safety, 4 (2). pp. 201-218.

Mallal, S., Pace, C., Nolan, D., Keller, J., Moore, C., Carvalho, F., Patterson, A., Sutton, K. and Gaudieri, S. (2005) Analysis of HIV-1 hypermutation and its relationship with APOBEC3G and vif genetic variation in vivo. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Nolan, D. and Mallal, S. (2005) Antiretroviral-therapy-associated lipoatrophy: current status and future directions. Sexual Health, 2 (3). pp. 153-163.

Hammond, E., Nolan, D., McKinnon, E., Pace, C., Metcalf, C. and Mallal, S. (2005) Assessing the contribution of ART, HIV and host factors to adipose tissue changes occurring in HIV-infected individuals: Risk profile for lipoatrophy. In: 7th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 16 November 2005, Dublin, Ireland

Gaudieri, S., Nolan, D., McKinnon, E., Witt, C.S., Mallal, S. and Christiansen, F.T. (2005) Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responses. Molecular Immunology, 42 (4). pp. 557-560.

Martin, A.M., Almeida, C., Nolan, D., Purcell, A., McCluskey, J., Phillips, E. and Mallal, S. (2005) Both the innate and adaptive immune systems are important in the pathogenesis of abacavir hypersensitivity reaction. In: Gordon Research Conference on Adverse Drug Reactions, 5 - 10 June 2005, New London, CT.

Lucas, A.D., Gaudieri, S., Rauch, A., Nolan, D. and Mallal, S. (2005) Cellular tropism of HIV-1 mediated and contrained by coreceptor dependencies. Journal of Viral Entry, 1 (1). pp. 17-27.

Almeida, C., Martin, A., Nolan, D., Cameron, P., James, I., Mifsud, N., Purcell, A., McCluskey, J. and Mallal, S. (2005) Chronic in vitro abacavir exposure elicits an immunological response in abacavir naive HIV positive individuals. In: 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment, 24 - 27 July 2005, Rio de Janeiro, Brazil.

Phillips, E.J., Wong, G., Kaul, R., Shahabi, K., Nolan, D., Knowles, S.R., Martin, A.M., Mallal, S. and Shear, N.H. (2005) Clinical and immunogenetic correlates of abacavir hypersensitivity. AIDS, 19 (9). pp. 979-981.

Nolan, D. (2005) Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy? Drug Safety, 28 (12). pp. 1069-1074.

Martin, A., Nolan, D., Rauch, A., Almeida, C., McKinnon, E. and Mallal, S. (2005) Genetic screening for Abacavir hypersensitivity (ABC-HSR) in the Western Australian cohort: Prospective data and novel diagnostic approaches. In: 17th Annual Conference of the Australasian Society for HIV Medicine (ASHM 2005), 24 - 27 August 2005, Hobart, Tasmania.

Gruters, R.A., Osterhaus, A.D.M.E., Nolan, D., James, I. and Mallal, S. (2005) HIV and smallpox. Science, 308 (5726). 1258b-1259b.

Nolan, D., James, I. and Mallal, S. (2005) HIV/AIDS: HIV: Experiencing the pressures of modern life. Science, 307 (5714). pp. 1422-1424.

Martin, A.M., Nolan, D. and Mallal, S. (2005) HLA-B*5701 typing by sequence-specific amplification: validation and comparison with sequence-based typing. Tissue Antigens, 65 (6). pp. 571-574.

Park, L., Goulder, P., Kiepiela, P., Brander, C., Walker, B., Korber, B., Szinger, J., Keller, J., John, M., Nolan, D. and Mallal, S. (2005) HLA-restricted immune responses have driven the evolution of HIV-1 clades. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Christiansen, F.T., Martin, A.M., Nolan, D.A., Gaudieri, S., Almeida, C., Phillips, E., Cameron, P.U., Moore, C.B., James, I. and Mallal, S.A. (2005) Host MHC influences susceptibility to hypersensitivity reactions to two drugs commonly used in HIV therapy. In: XIX European Immunogenetics & Histocompatibility Conference, 23 - 26 April 2005, Istanbul, Turkey.

Martin, A.M., Almeida, C., Nolan, D., Cameron, P., Purcell, A., Chessman, D., McCluskey, J., Phillips, E. and Mallal, S. (2005) Involvement of metabolic and immune responses in the pathogenesis of Abacavir hypersensitivity reaction. In: 17th Annual Conference of the Australasian Society for HIV Medicine (ASHM 2005), 24 - 27 August 2005, Hobart, Tasmania.

Gaudieri, S., DeSantis, D., McKinnon, E., Moore, C., Nolan, D., Witt, C.S., Mallal, S.A. and Christiansen, F.T. (2005) Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes and Immunity, 6 (8). pp. 683-690.

Balakrishnan, K., Verdile, G., Mehta, P.D., Beilby, J., Nolan, D., Galvão, D.A., Newton, R., Gandy, S.E. and Martins, R.N. (2005) Plasma Aβ42 correlates positively with increased body fat in healthy individuals. Journal of Alzheimer's disease : JAD, 8 (3). pp. 269-282.

Martin, A.M., Nolan, D., James, I., Cameron, P., Keller, J., Moore, C., Phillips, E., Christiansen, F.T. and Mallal, S. (2005) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS, 19 (1). pp. 97-99.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2005) Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV Cohort. In: 7th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 16 November 2005, Dublin, Ireland.

Martin, A.M., Almeida, C., Nolan, D. and Mallal, S. (2005) TLR2 and CD14 receptors are essential for abacavir induced HSP70 signalling and dendritic cell activation. In: ANS Apoptosis and Immunity 2005, 31 May 2005, Cairns, Australia.

Mallon, P., Sedwell, R., Rogers, G., Nolan, D., Unemori, P., Wand, H., Samaras, K., Kelleher, A., Emery, S., Cooper, D., Carr, A. and Mallal, S. (2005) The effect of rosiglitazone on PPARg expression in human adipose tissue Is limited by continued exposure to thymidine NRTI. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

2004

Mallal, S., Almeida, C., Nolan, D. and Martin, A. (2004) Abacavir hypersensitivity as a model for elucidating Class I-restricted drug reactions. In: 7th International Meeting of the International Society for the Study of Xenobiotics, 29 August - 2 September 2004, Vancouver, Canada.

Wong, G., Kaul, R., Shahabi, K., Nolan, D., Mallal, S., Knowles, S., Martin, A., Shear, N. and Phillips, E. (2004) Abacavir hypersensitivity syndrome: Results of clinical, immunological and genetic screening. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

Martin, A.M., Almeida, C., Nolan, D., Gaudieri, S., James, I., Christiansen, F.T., Purcell, A., McCluskey, J. and Mallal, S. (2004) Carriage of HLA-B*5701 and a haplotypic Hsp70-Hom variant is associated with a Class I MHC-restricted hypersensitivity response to abacavir. In: 11th Conference on Retroviruses and Opportunistic Infections, 8 - 11 February 2004, Washington DC, U.S.A.

Nolan, D. and Mallal, S. (2004) Complications associated with NRTI therapy: Update on clinical features and possible pathogenic mechanisms. Antiviral Therapy, 9 (6). pp. 849-863.

Hammond, E., Nolan, D., James, I., McKinnon, E. and Mallal, S. (2004) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipoatrophy in HIV infected patients: A model of drug induced mitochondrial toxicity. In: Mitochodrial Medicine 2004, 4 - 8 August 2004, Pittsburgh, PA.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2004) Differential effects of nucleoside reverse transcriptase inhibitor (NRTI) regimens on adipocyte mitochondrial DNA depletion in HIV-infected patients. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

Nolan, D., Gaudieri, S., John, M. and Mallal, S. (2004) Impact of host genetics on HIV disease progression and treatment: New conflicts on an ancient battleground. AIDS, 18 (9). pp. 1231-1240.

Almeida, C., Martin, A., Nolan, D. and Mallal, S. (2004) Increase in inflammatory cytokine levels in abacavir stimulated mononuclear cells from HIV infected patients with abacavir hypersensitivity. In: 16th Annual Conference of the Australasian Society for HIV Medicine , 2 - 4 September 2004, Canberra, Australia

Christiansen, F.T., Gaudieri, S., De Santis, D., McKinnon, E., Moore, C., Nolan, D. and Mallal, S. (2004) NK receptor haplotypes and HLA as predictors of HIV-1 progression. In: NK2004 Workshop, 24 - 28 April 2004, Noordwijkerhout, The Netherlands.

Burkhardt, M.S., Foster, J.K., Laws, S.M., Baker, L.D., Craft, S., Gandy, S.E., Stuckey, B.G.A., Clarnette, R., Nolan, D., Hewson-Bower, B. and Martins, R.N. (2004) Oestrogen replacement therapy may improve memory functioning in the absence of APOE e4. Journal of Alzheimer's disease : JAD, 6 (3). pp. 221-228.

Martin, A.M., Nolan, D., Gaudieri, S., Phillips, E. and Mallal, S. (2004) Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity. Pharmacogenomics, 5 (6). pp. 643-655.

Nolan, D. and Pace, C. (2004) Potential roles for uncoupling proteins in HIV lipodystrophy. Mitochondrion, 4 (2-3). pp. 185-191.

Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., James, I., Phillips, E. and Mallal, S. (2004) Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences, 101 (12). pp. 4180-4185.

Martin, A., Cameron, P., Nolan, D., James, I., Keller, J., Phillips, E. and Mallal, S. (2004) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*01 and higher CD4+ T cell counts. In: XV International AIDS Conference, 11 - 16 July 2004, Bangkok, Thailand.

Hammond, E., Nolan, D., James, I., Metcalf, C. and Mallal, S. (2004) Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6-12 months of commencing nucleoside reverse transcriptase inhibitor therapy. AIDS, 18 (5). pp. 815-817.

Nolan, D. and Mallal, S. (2004) The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome. Journal of HIV Therapy, 9 (2). pp. 34-40.

2003

Nolan, D. and Christiansen, F. (2003) 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV. Expert Opinion on Drug Safety, 2 (1). pp. 95-101.

Nolan, R., Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., Carvalho, F., Witt, C., Sayer, D., Herrmann, S., Christiansen, F.T. and Mallal, S. (2003) Abacavir Hypersensitivity Syndrome: Clarifying genetic associations by including the presence of an abacavir specific immune response in diagnostic criteria. In: 15th Annual Conference of the Australian Society for HIV Medicine, 22 - 25 October, Cairns, Australia.

Martin, A.M., Hammond, E., Nolan, D., Pace, C., den Boer, M., Taylor, L., Moore, H., Martinez, O.P., Christiansen, F.T. and Mallal, S. (2003) Accumulation of mitochondrial DNA mutations in Human Immunodeficiency Virus–infected patients treated with Nucleoside-analogue Reverse-transcriptase inhibitors. American Journal of Human Genetics, 72 (3). pp. 549-560.

Martin, A.M., Hammond, E., Nolan, D., Pace, C., den Boer, M., Taylor, L., Moore, H., Martinez, O.P., Christiansen, F.T. and Mallal, S. (2003) Accumulation of mitochondrial DNA mutations in human immunodeficiency Virus–infected patients treated with Nucleoside-analogue Reverse-transcriptase inhibitors. The American Journal of Human Genetics, 72 (3). p. 1358.

Hammond, E.L., Sayer, D., Nolan, D., Walker, U.A., de Ronde, A., Montaner, J.S.G., Côté, H.C.F., Gahan, M.E., Cherry, C.L., Wesselingh, S.L., Reiss, P. and Mallal, S. (2003) Assessment of precision and concordance of quantitative mitochondrial DNA assays: A collaborative international quality assurance study. Journal of Clinical Virology, 27 (1). pp. 97-110.

James, I., Nolan, D., McKinnon, E., Hammond, E. and Mallal, S. (2003) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipodystrophy: Trends in subcutaneous fat wasting and association with mitochondrial DNA depletion. In: 7th International Workshop on HIV Observational Databases, 28-30 March 2003, Fiuggi, Italy.

Nolan, D., Hammond, E., James, I., McKinnon, E. and Mallal, S. (2003) Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antiviral Therapy, 8 (6). pp. 617-626.

Pace, C., Martin, A., Mamotte, C., Hammond, E., Nolan, D. and Mallal, S. (2003) Effects of HAART on expression (mRNA) of PPAR-gamma, UCP2, UCP1, mitochondrial DNA depletion and proliferation. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Nolan, D., Watts, G.F., Herrmann, S.E., French, M.A., John, M. and Mallal, S. (2003) Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk? QJM, 96 (11). pp. 825-832.

Hammond, E., Nolan, D., James, I., McKinnon, E., White, A. and Mallal, S. (2003) Evidence of toxicity in Adipose tissue of HIV-infected patients correlates with NRTI-associated mtDNA depletion. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Cherry, C., Nolan, D., James, I., Mallal, S., McKinnon, E., French, M., Hammond, E., Gahan, M., McArthur, J. and Wesselingh, S. (2003) Longitudinal associations between antiretroviral treatments and quantification of tissue mitochondrial DNA from ambulatory subjects with HIV infection. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

James, I., Nolan, D., Hammond, E., McKinnon, E. and Mallal, S. (2003) Longitudinal effects on subcutaneous fatmass of initiating or switching stavudine and zidovudine-based antiretroviral therapy. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Martin, A., Gaudieri, S., Witt, C., Nolan, D., Christiansen, F.T. and Mallal, S. (2003) Mapping of genetic susceptibility to abacavir hypersensitivity. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Nolan, D. (2003) Metabolic complications associated with HIV protease inhibitor therapy. Drugs, 63 (23). pp. 2555-2574.

Nolan, D., Hammond, E., Martin, A., Taylor, L., Herrmann, S., McKinnon, E., Metcalf, C., Latham, B. and Mallal, S. (2003) Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS, 17 (9). pp. 1329-1338.

Pace, C.S., Martin, A.M., Hammond, E.L., Mamotte, C.D.S., Nolan, D.A. and Mallal, S.A. (2003) Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antiviral Therapy, 8 (4). pp. 323-331.

Nolan, D., Gaudieri, S. and Mallal, S. (2003) Pharmacogenetics: A practical role in predicting antiretroviral drug toxicity? Journal of HIV therapy, 8 (2). pp. 36-41.

John, M., McKinnon, E.J., James, I.R., Nolan, D., Herrmann, S.E., Moore, C.B., White, A.J. and Mallal, S.A. (2003) Randomised, controlled, 48-week study of switching stavudine and/or protease inhibitors to Combavir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33 (1). pp. 29-34.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2003) Subcutaneous fat tissue mitochondrial DNA depletion and adipose toxicity are strongly associated with nucleoside reverse transcriptase inhibitor (NRTI) therapy in HIV-infected patients. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Nolan, D. and Mallal, S. (2003) Thymidine analogue-sparing highly active antiretroviral therapy (HAART). Journal of HIV therapy, 8 (1). pp. 1-5.

Nolan, D., Moore, C., Castley, A., Sayer, D., Marmotte, C., John, M., James, I. and Mallal, S. (2003) Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS, 17 (1). pp. 121-123.

Martin, A., Nolan, D., Gaudieri, S., Almeida, C., Carvalho, F., Witt, C., Sayer, D., Nolan, R., Herrmann, S., Christiansen, F. and Mallal, S. (2003) Updated experience of abacavir hypersensitivity genetic testing within the major histocompatibility complex (MHC): addressing diagnostic precision and predictive value. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Christiansen, F.T., Gaudieri, S., Moore, C.B., Martin, A., Nolan, D., James, I.R., McKinnon, E., DeSantis, D., Witt, C.S. and Mallal, S. (2003) The immune response to HIV: The interplay between virus and host genetic factors. In: British Society for Immunology Annual Congress, 2 - 5 December 2003, Harrogate, England.

2002

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A.M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F.T. (2002) Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. The Lancet, 359 (9308). pp. 727-732.

Hammond, E., Nolan, D., McKinnon, E. and Mallal, S. (2002) No evidence of mitochondrial DNA depletion in peripheral white blood cells after three to 12 months of HAART. In: XIV International AIDS conference, 7 - 12 July 2002, Barcelona, Spain

Nolan, D., James, I., McKinnon, E. and Mallal, S. (2002) Stavudine, zidovudine and protease inhibitor therapy effects on subcutaneous leg fat wasting in HIV-infected males. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Nolan, D., Moore, C., Castley, A., Sayer, D., Mamotte, C., John, M., James, I. and Mallal, S. (2002) Tumour necrosis factor alpha gene - 238G/A promoter polymorphism associated with more rapid onset of lipodystrophy. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Mallal, S., Witt, C., Martin, A.M., Masel, G., Moore, C., Sayer, D., Castley, A., Mamotte, C., Nolan, D., James, I. and Christiansen, F.T. (2002) The presence of HLA-B*5701, -DRB1*0701 and -DQ3 is highly predictive of hypersensitivity to the HIV reverse transcriptase inihibitor abacavir. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A.

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F. (2002) The presence of HLA-B*5701, -DRB1*0701, and -DQ3 Is highly predictive of hypersensitivity to the HIV reverse transcriptase inhibitor abacavir. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A

John, M., James, I., McKinnon, E., Nolan, D., Herrmann, S., Cain, A., Martinez, O.P., White, A. and Mallal, S. (2002) A randomised, controlled, Open-label study of revision of antiretroviral regimens containing stavudine (d4T) and/or a Protease Inhibitor (PI) to Zidovudine (ZDV)/Lamivudine (3TC)/Abacavir (ABC) to prevent or reverse lipoatrophy: 48-week data. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

Hammond, E., Nolan, D., Martin, A., Sayer, D. and Mallal, S. (2002) A real-time PCR-based method for detecting mitochondrial DNA depletion: Assessment of assay precision. In: Keystone Symposia on Mitochondria and Pathogenesis, 6 - 12 April 2002, Copper Mountain, Colorado

2001

Nolan, D., John, M. and Mallal, S. (2001) Antiretoviral therapy and the lipodystrophy syndrome, part 2: Concepts in aetiopathogenesis. Antiviral Therapy, 6 (3). pp. 145-160.

John, M., Nolan, D. and Mallal, S. (2001) Antiretroviral therapy and the lipodystrophy syndrome. Antiviral Therapy, 6 (1). pp. 9-20.

John, M., Moore, C.B., James, I.R., Nolan, D., Upton, R.P., McKinnon, E.J. and Mallal, S.A. (2001) Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS, 15 (6). pp. 717-723.

James, I., Moore, C., John, M., Nolan, D., McKinnon, E. and Mallal, S. (2001) Effect of HAART on subcutaneous fat in HIV-infected males: A longitudinal study. In: 5th International Workshop on HIV Observational Databases, 26 - 27 April 2001, Monte Carlo

Nolan, D. and Mallal, S. (2001) Effects of sex and race on lipodstrophy pathogenesis. Journal of HIV therapy, 6 (1). pp. 32-36.

Nolan, D. and Mallal, S. (2001) Getting to the HAART of insulin resistance. AIDS, 15 (15). pp. 2037-2041.

Mallal, S., Hammond, E., Martin, A. and Nolan, D.A. (2001) Mitochondrial DNA depletion in adipocytes associated with NRTI treatment in HIV infected individuals. In: 8th European Conference of Clinical Aspects and Treatment of HIV-Infection, 27 - 31 October 2001, Athens, Greece

Hammond, E.L., Martin, A., Taylor, L., John, M., Nolan, D.A. and Mallal, S. (2001) Mitochondrial DNA depletion, assessed by real-time PCR-based quantitative assay in subcutaneous fat of HIV infected patients: Evidence for a role in the aetiology of fat wasting. In: 4th International Conference on Nutrition and HIV infection/2nd European Workshop on Lipodystrophy, 19 - 21 April 2001, Cannes, France

Nolan, D., Hammond, E., Martin, A., Metcalf, C., Latham, B., John, M. and Mallal, S. (2001) NRTI therapy is associated with mitochondrial DNA depletion, increased mitochondrial biogenesis and subcutaneous fat wasting in HIV infected patients. In: 1st IAS Conference on HIV Pathogenesis and Treatment, 8 - 11 July 2001, Buenos Aires, Argentina

Nolan, D. (2001) Review of the Third International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Athens, 2001. Nutrition and Metabolic Disorders in HIV Infection, 2002 (1). pp. 1-14.

Nolan, D., Upton, R., McKinnon, E., John, M., James, I., Adler, B., Roff, G., Vasikaran, S. and Mallal, S. (2001) Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir. AIDS, 15 (10). pp. 1275-1280.

2000

Mallal, S., Moore, C., John, M., James, I., Nolan, D., Sayer, D. and Witt, C. (2000) Characteristic changes in HIV reverse trancriptase sequence at sites encoding known CTL epitopes at a population level. In: XIII International AIDS Conference, 9 - 14 July 2000, Durban, South Africa

Nolan, D., Mallal, S. and John, M. (2000) Developing tools for investigation of mitochondrial toxicity in the clinical setting. In: Forum for Collaborative HIV Research: Mitochondrial Toxicity and HIV Disease Meeting, 5 - 6 June 2000, Washington, DC.

Gizzarelli, L., Hammond, E., Martin, A., Nolan, D. and Mallal, S. (2000) Level of heteroplasmy DNA detection in mtDNA using SSCP and DNA sequencing. In: 12th Annual Conference of the Australian Society for HIV Medicine, 12 - 14 October 2000, Melbourne, Australia

Mallal, S., Nolan, D., John, M., Chong, D., Metcalf, C. and Latham, B. (2000) Light and electron microscopy findings in subcutaneous fat antiretroviral treated and HIV-infected patients. In: XIII International AIDS Conference, 9 - 14 July 2000, Durban, South Africa.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of bone mineral density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat: With an additional independent effect of indinavir therapy to increase BMD. Antiviral Therapy, 5 (Supp. 5).

John, M., Moore, C., James, I., Nolan, D., Upton, R. and Mallal, S. (2000) Predictors of lactic acidemia in the WA HIV cohort. In: Fourth International Cohorts Meeting on HIV Observational Databases, 30 - 31 March 2000, Marbella, Spain

John, M., Moore, C., James, I., Nolan, D. and Mallal, S. (2000) Predictors of response to antiretroviral therapy in the WA HIV cohort. In: Fourth International Cohorts Meeting on HIV Observational Databases, 30 - 31 March 2000, Marbella, Spain

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This list was generated on Thu Jul 24 09:26:34 2014 IST.