Publications: McKinnon, Elizabeth

Journal Article

Bronke, C., Almeida, C.M., McKinnon, E., Roberts, S.G., Keane, N.M., Chopra, A., Carlson, J.M., Heckerman, D., Mallal, S. and John, M. (2013) HIV escape mutations occur preferentially at HLA-binding sites of CD8 T-cell epitopes. AIDS, 27 (6). pp. 899-905.

Herrmann, S., McKinnon, E., Hyland, N.B., Lalanne, C., Mallal, S., Nolan, D., Chassany, O. and Duracinsky, M. (2013) HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection. Health and Quality of Life Outcomes, 11 (1).

Hammond, E., McKinnon, E., Glendenning, P., Williams, R., Mallal, S. and Phillips, E. (2012) Association between 25-OH vitamin D and insulin is independent of lipoatrophy in HIV. Clinical Endocrinology, 76 (2). pp. 201-206.

Reeves, K.L., McKinnon, E.J. and James, I.R. (2012) Correction for founder effects in host-viral association studies via principal components. Statistical Applications in Genetics and Molecular Biology, 11 (4).

Gaudieri, S., Lucas, M., Lucas, A., McKinnon, E., Albloushi, H., Rauch, A., di Iulio, J., Martino, D., Prescott, S.L. and Tulic, M.K. (2012) Genetic variations in IL28B and allergic disease in children. PLoS ONE, 7 (1). e30607.

Almeida, C.M., Bronke, C., Roberts, S.G., McKinnon, E., Keane, N.M., Chopra, A., Kadie, C., Carlson, J., Haas, D. W., Riddler, S. A., Haubrich, R., Heckerman, D., Mallal, S. and John, M. (2011) Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes. The Journal of Immunology, 187 (5). pp. 2502-2513.

Lucas, M., Nicol, P., McKinnon, E., Whidborne, R., Lucas, A.D., Thambiran, A., Burgner, D., Waring, J. and French, M. (2011) The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children. Thorax, 66 (3). p. 265.

Almeida, C.M., Roberts, S.G., Laird, R., McKinnon, E., Ahmad, I., Keane, N.M., Chopra, A., Kadie, C., Heckerman, D., Mallal, S. and John, M. (2010) Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses. Vaccine, 28 (37). pp. 6052-6057.

Hammond, E.L., McKinnon, E. and Nolan, D. (2010) Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences. Clinical Infectious Diseases, 51 (5). pp. 591-599.

Herrmann, S.E., McKinnon, E.J., Williams, L.J., John, M., Mallal, S., Lucas, M. and Nolan, D.A. (2010) Use of alcohol, nicotine and other drugs in the Western Australian HIV Cohort study. Sexual Health, 9 (2). pp. 199-201.

Lucas, M., Nicol, P., McKinnon, E., Whidborne, R., Lucas, A.D., Thambiran, A., Burgner, D., Waring, J. and French, M. (2010) A prospective large-scale study of methods for the detection of latent Mycobacterium tuberculosis infection in refugee children. Thorax, 65 (5). pp. 442-448.

D'Orsogna, L.J., Wright, M.P., Krueger, R.G., McKinnon, E.J., Buffery, S.I., Witt, C.S., Staples, N., Loh, R., Cannell, P.K., Christiansen, F.T. and French, M.A. (2009) Allogeneic hematopoietic stem cell transplantation recipients have defects of both switched and IgM memory B cells. Biology of Blood and Marrow Transplantation, 15 (7). pp. 795-803.

McKinnon, E., Morahan, G., Nolan, D. and James, I. (2009) Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 92-100.

Almeida, C.M., Roberts, S.G., Laird, R., McKinnon, E., Ahmad, I., Pfafferott, K., Turley, J., Keane, N.M., Lucas, A.D., Rushton, B.C., Chopra, A., Mallal, S. and John, M. (2009) Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses. Journal of Immunological Methods, 344 (1). pp. 1-5.

Morahan, G., Mehta, M., McKinnon, E. and James, I. (2009) Effect of linkage status of affected sib-pairs on the search for novel type 1 diabetes susceptibility genes in the HLA complex. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 67-73.

James, I., McKinnon, E., Gaudieri, S. and Morahan, G. (2009) Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 101-107.

Rauch, A., Nolan, D., Furrer, H., McKinnon, E., John, M., Mallal, S., Gaudieri, S., Günthard, H.F., Schmid, P., Battegay, M., Hirschel, B., Telenti, A., James, I. and Swiss HIV Cohort Study, . (2008) HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy. Clinical Infectious Diseases, 46 (12). pp. 1921-1925.

Hammond, E.L., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. AIDS, 22 (18). pp. 2540-2543.

D'Orsogna, L.J., Krueger, R.G., McKinnon, E.J. and French, M.A. (2007) Circulating memory B-cell subpopulations are affected differently by HIV infection and antiretroviral therapy. AIDS, 21 (13). pp. 1747-1752.

Rauch, A., Laird, R., McKinnon, E., Telenti, A., Furrer, H., Weber, R., Smillie, D. and Gaudieri, S. (2007) Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection. Tissue Antigens, 69 (SUPPL. 1). pp. 237-240.

French, M.A., Keane, N.M., McKinnon, E.J., Phung, S. and Price, P. (2007) Susceptibility to opportunistic infections in HIV-infected patients with increased CD4 T-cell counts on antiretroviral therapy may be predicted by markers of dysfunctional effector memory CD4 T cells and B cells. HIV Medicine, 8 (3). pp. 148-155.

Herrmann, S., McKinnon, E., John, M., Hyland, N., Martinez, O.P., Cain, A., Turner, K., Coombs, A., Manolikos, C. and Mallal, S. (2007) Evidence-based, multifactorial approach to addressing non-adherence to antiretroviral therapy and improving standards of care. Internal Medicine Journal, 38 (1). pp. 8-15.

Fernandez, S., Price, P., McKinnon, E.J., Nolan, R.C. and French, M.A. (2006) Low CD4+ T-cell counts in HIV patients receiving effective antiretroviral therapy are associated with CD4+ T-cell activation and senescence but not with lower effector memory T-cell function. Clinical Immunology, 120 (2). pp. 163-170.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2006) Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study. Clinical Infectious Diseases, 43 (1). pp. 99-102.

Price, P., Keane, N.M., Lee, S., Lim, A.F.Y., McKinnon, E.J. and French, M.A. (2006) A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to antiretroviral therapy. Immunology, 119 (1). pp. 74-82.

Cherry, C.L., Nolan, D., James, I.R., McKinnon, E.J., Mallal, S.A., Gahan, M.E., Lal, L., McArthur, J.C. and Wesselingh, S.L. (2006) Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-Infected individuals. JAIDS Journal of Acquired Immune Deficiency Syndromes, 42 (4). pp. 435-440.

Gaudieri, S., Nolan, D., McKinnon, E., Witt, C.S., Mallal, S. and Christiansen, F.T. (2005) Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responses. Molecular Immunology, 42 (4). pp. 557-560.

Gaudieri, S., DeSantis, D., McKinnon, E., Moore, C., Nolan, D., Witt, C.S., Mallal, S.A. and Christiansen, F.T. (2005) Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes and Immunity, 6 (8). pp. 683-690.

Suter, R.J., McKinnon, E.J., Perkins, N.R. and Besier, R.B. (2005) The effective life of ivermectin on Western Australian sheep farms—A survival analysis. Preventive Veterinary Medicine, 72 (3-4). pp. 311-322.

Nolan, D., Hammond, E., James, I., McKinnon, E. and Mallal, S. (2003) Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antiviral Therapy, 8 . pp. 617-626.

Nolan, D., Hammond, E., Martin, A., Taylor, L., Herrmann, S., McKinnon, E., Metcalf, C., Latham, B. and Mallal, S. (2003) Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS, 17 (9). pp. 1329-1338.

John, M., McKinnon, E.J., James, I.R., Nolan, D., Herrmann, S.E., Moore, C.B., White, A.J. and Mallal, S.A. (2003) Randomised, controlled, 48-week study of switching stavudine and/or protease inhibitors to Combavir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33 (1). pp. 29-34.

McKinnon, E.J., James, I.R., John, M. and Mallal, S.A. (2003) Viral load detectability profiles for HIV infection. Statistics in Medicine, 22 (3). pp. 385-396.

John, M., Moore, C.B., James, I.R., Nolan, D., Upton, R.P., McKinnon, E.J. and Mallal, S.A. (2001) Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS, 15 (6). pp. 717-723.

Nolan, D., Upton, R., McKinnon, E., John, M., James, I., Adler, B., Roff, G., Vasikaran, S. and Mallal, S. (2001) Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir. AIDS, 15 (10). pp. 1275-1280.

Mallal, S.A., John, M., Moore, C.B., James, I.R. and McKinnon, E.J. (2000) Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS, 14 (10). pp. 1309-1316.

French, M.A., Lenzo, N., John, M., Mallal, S.A., McKinnon, E.J., James, I.R., Price, P., Flexman, J.P. and Tay-Kearney, M-L (2000) Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Medicine, 1 (2). pp. 107-115.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of bone mineral density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat: With an additional independent effect of indinavir therapy to increase BMD. Antiviral Therapy, 5 (Supp. 5).

Conference Paper

Herrmann, S.E., McKinnon, E., John, M. and Mallal, S. (2007) Influence of dosing regimen on adherence to antiretroviral therapy within PI and NNRTI regimens. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

James, I., McKinnon, E. and Mallal, S. (2002) Comparison of rates of progression in HIV observational cohorts. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal.

McKinnon, E., John, M., James, I. and Mallal, S. (2002) Effect of baseline CD4 on virological response to first HAART. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal.

Hammond, E., Nolan, D., McKinnon, E. and Mallal, S. (2002) No evidence of mitochondrial DNA depletion in peripheral white blood cells after three to 12 months of HAART. In: XIV International AIDS conference, 7 - 12 July 2002, Barcelona, Spain.

McKinnon, E., James, I. and Mallal, S. (2002) Progessive matching in HIV observational studies. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal.

James, I., Moore, C., John, M., Nolan, D., McKinnon, E. and Mallal, S. (2001) Effect of HAART on subcutaneous fat in HIV-infected males: A longitudinal study. In: 5th International Workshop on HIV Observational Databases, 26 - 27 April 2001, Monte Carlo.

John, M., Moore, C., James, I., McKinnon, E. and Mallal, S. (2000) Relative contribution of NRTIs, NNRTIs and PIs to chronic asymptomatic lactic acidaemia in HIV infected patients. In: European Symposium on Lipodyctrophy and HIV Infection, 24 - 25 March 2000, Marrakesh, Morocco.

Mallal, S., John, M., Moore, C., James, I. and McKinnon, E. (1999) Protease inhibitors and nucleoside analogue reverse transcriptase inhibitors interact to cause subcutaneous fat wasting in patients with HIV infection. In: 7th European Conference on Clinical Aspects and Treatment of HIV-Infection , 23 - 27 October 1999, Lisbon, Portugal.

Conference Item

Herrmann, S., Williams, L., McKinnon, E. and Nolan, D. (2010) Vulnerable populations: Substance use in the WA HIV Cohort Study. In: 17th Western Australian Drug and Alcohol Symposium, 30 August - 1 September, Fremantle, Western Australia.

Almeida, C., Bronke, C., Roberts, S., Cooper, D., Corkery, M., McKinnon, E., Ahmad, I., Keane, N., Chopra, A., Mallal, S., John, M. and Heckerman, D. (2009) Identification of multiple novel HIV-specific T-cell epitopes using HLA-associated HIV polymorphisms. In: 39th Annual Scientific Meeting of the Australasian Society for Immunology 2009, 6 - 10 December 2009, Gold Coast, QLD.

Herrmann, S., Williams, L., McKinnon, E. and Nolan, D. (2009) Substance use in the WA HIV Cohort: 2002-2008. In: 21st Annual Conference of the Australasian Society for HIV Medicine (ASHM), 9 - 11 September, Brisbane, Australia.

Duracinsky, M., Herrmann, S., Acquadro, C., Berzins, B., Le Coeur, S., Hyland, N., Fournier, I., McKinnon, E., Nolan, D., Mallal, S. and Chassany, O. (2008) Development of a new health-related quality of life questionnaire specific to HIV/AIDS: an international and cross cultural initiative. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Herrmann, S., McKinnon, E., John, M., Nolan, D., Martinez, O.P., Phillips, E. and Mallal, S. (2008) Side effects, dosing schedules, pill burden and perceived stress: interaction and influence on medication. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

McKinnon, E., John, M., Herrmann, S.E. and James, I. (2007) Models and analysis of point-inflated data in a study of markers of HAART efficacy. In: 11th International Workshop on HIV Observational Databases, 22 - 25 March, Monte Carlo.

Cain, A., Coombs, A., Turner, K., Hyland, N., Manolikos, C., Herrmann, S.E., McKinnon, E., Williams, L., Skett, J., Forsdyke, C., Martinez, P. and French, M. (2007) Shared care: enabling access to hospital treatment for PLWHA with complex lifestyles. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Martin, A., Nolan, D., Rauch, A., Almeida, C., McKinnon, E. and Mallal, S. (2005) Genetic screening for Abacavir hypersensitivity (ABC-HSR) in the Western Australian cohort: Prospective data and novel diagnostic approaches. In: 17th Annual Conference of the Australasian Society for HIV Medicine (ASHM 2005), 24 - 27 August 2005, Hobart, Tasmania.

Herrmann, S., McKinnon, E. and Mallal, S. (2004) Combining adherence monitoring with patient education in the Royal Perth Hospital Immunology Outpatient Clinic. In: 16th Annual Conference of the Australasian Society for HIV Medicine, 2 - 4 September, Canberra, Australia.

Herrmann, S., Hyland, N., Coombs, A., Turner, K., Duncan, F., McKinnon, E., James, I., Martinez, O.P., French, M. and Mallal, S. (2003) Adherence to antiretroviral therapy in the WA HIV Cohort. In: 15th Annual Conference of the Australian Society for HIV Medicine, 22 - 25 October, Cairns, Australia.

John, M., James, I., McKinnon, E., Nolan, D., Herrmann, S., Cain, A., Martinez, O.P., White, A. and Mallal, S. (2002) A randomised, controlled, Open-label study of revision of antiretroviral regimens containing stavudine (d4T) and/or a Protease Inhibitor (PI) to Zidovudine (ZDV)/Lamivudine (3TC)/Abacavir (ABC) to prevent or reverse lipoatrophy: 48-week data. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada.