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Publications: Martin, Annalise M.

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Number of items: 45.

Journal Article

Martin, A., Amin, J., Cooper, D.A., Carr, A., Kelleher, A.D., Bloch, M., Baker, D., Woolley, I., Emery, S. and Nolan, D. (2010) Abacavir does not affect circulating levels of inflammatory or coagulopathic biomarkers in suppressed HIV: A randomized clinical trial. AIDS, 24 (17). pp. 2657-2663.

Hammond, E.L., Martin, A., Nolan, D., Metcalf, C. and Mallal, S. (2008) Eruptive haemangioma associated with HIV therapy and mitochondrial pathology. Pathology, 40 (4). pp. 425-429.

Martin, A., Almeida, C.M., Cameron, P.U., Purcell, Anthony W, Nolan, D., James, I., McCluskey, J., Phillips, E.J., Landay, Alan and Mallal, S. (2007) Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS, 21 (10). pp. 1233-1244.

Martin, A., Nolan, D., Almeida, C., Rauch, A. and Mallal, S. (2006) Predicting and diagnosing abacavir and nevirapine drug hypersensitivity: from bedside to bench and back again. Pharmacogenomics, 7 (1). pp. 15-23.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2006) Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study. Clinical Infectious Diseases, 43 (1). pp. 99-102.

Phillips, E.J., Wong, G., Kaul, R., Shahabi, K., Nolan, D., Knowles, S.R., Martin, A.M., Mallal, S. and Shear, N.H. (2005) Clinical and immunogenetic correlates of abacavir hypersensitivity. AIDS, 19 (9). pp. 979-981.

Martin, A.M., Nolan, D. and Mallal, S. (2005) HLA-B*5701 typing by sequence-specific amplification: validation and comparison with sequence-based typing. Tissue Antigens, 65 (6). pp. 571-574.

Martin, A.M., Nolan, D., James, I., Cameron, P., Keller, J., Moore, C., Phillips, E., Christiansen, F.T. and Mallal, S. (2005) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS, 19 (1). pp. 97-99.

Martin, A.M., Kulski, J.K., Gaudieri, S., Witt, C.S., Freitas, E.M., Trowsdale, J. and Christiansen, F.T. (2004) Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B. Gene, 335 . pp. 121-131.

Martin, A.M., Nolan, D., Gaudieri, S., Phillips, E. and Mallal, S. (2004) Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity. Pharmacogenomics, 5 (6). pp. 643-655.

Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., James, I., Phillips, E. and Mallal, S. (2004) Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences, 101 (12). pp. 4180-4185.

Martin, A.M., Smith, D., Carr, A., Hoy, J., Chuah, J., Mallal, S., Law, M., Clements, M. and Cooper , D.A. (2004) Progression of Lipodystrophy (LD) with continued thymidine analogue usage: Long-term Follow-Up from a randomized clinical trial (The PIILR Study). HIV Clinical Trials, 5 (4). pp. 192-200.

Martin, A.M., Hammond, E., Nolan, D., Pace, C., den Boer, M., Taylor, L., Moore, H., Martinez, O.P., Christiansen, F.T. and Mallal, S. (2003) Accumulation of mitochondrial DNA mutations in Human Immunodeficiency Virus–infected patients treated with Nucleoside-analogue Reverse-transcriptase inhibitors. American Journal of Human Genetics, 72 (3). pp. 549-560.

Nolan, D., Hammond, E., Martin, A., Taylor, L., Herrmann, S., McKinnon, E., Metcalf, C., Latham, B. and Mallal, S. (2003) Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS, 17 (9). pp. 1329-1338.

Pace, C.S., Martin, A.M., Hammond, E.L., Mamotte, C.D.S., Nolan, D.A. and Mallal, S.A. (2003) Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antiviral Therapy, 8 (4). pp. 323-331.

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A.M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F.T. (2002) Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. The Lancet, 359 (9308). pp. 727-732.

Conference Paper

Almeida, C., Martin, A., Nolan, D. and Mallal, S. (2004) Increase in inflammatory cytokine levels in abacavir stimulated mononuclear cells from HIV infected patients with abacavir hypersensitivity. In: 16th Annual Conference of the Australasian Society for HIV Medicine , 2 - 4 September 2004, Canberra, Australia

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F. (2002) The presence of HLA-B*5701, -DRB1*0701, and -DQ3 Is highly predictive of hypersensitivity to the HIV reverse transcriptase inhibitor abacavir. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A

Hammond, E., Nolan, D., Martin, A., Sayer, D. and Mallal, S. (2002) A real-time PCR-based method for detecting mitochondrial DNA depletion: Assessment of assay precision. In: Keystone Symposia on Mitochondria and Pathogenesis, 6 - 12 April 2002, Copper Mountain, Colorado

Mallal, S., Hammond, E., Martin, A. and Nolan, D.A. (2001) Mitochondrial DNA depletion in adipocytes associated with NRTI treatment in HIV infected individuals. In: 8th European Conference of Clinical Aspects and Treatment of HIV-Infection, 27 - 31 October 2001, Athens, Greece

Hammond, E.L., Martin, A., Taylor, L., John, M., Nolan, D.A. and Mallal, S. (2001) Mitochondrial DNA depletion, assessed by real-time PCR-based quantitative assay in subcutaneous fat of HIV infected patients: Evidence for a role in the aetiology of fat wasting. In: 4th International Conference on Nutrition and HIV infection/2nd European Workshop on Lipodystrophy, 19 - 21 April 2001, Cannes, France

Nolan, D., Hammond, E., Martin, A., Metcalf, C., Latham, B., John, M. and Mallal, S. (2001) NRTI therapy is associated with mitochondrial DNA depletion, increased mitochondrial biogenesis and subcutaneous fat wasting in HIV infected patients. In: 1st IAS Conference on HIV Pathogenesis and Treatment, 8 - 11 July 2001, Buenos Aires, Argentina

Gizzarelli, L., Hammond, E., Martin, A., Nolan, D. and Mallal, S. (2000) Level of heteroplasmy DNA detection in mtDNA using SSCP and DNA sequencing. In: 12th Annual Conference of the Australian Society for HIV Medicine, 12 - 14 October 2000, Melbourne, Australia

Conference Item

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Laird, R., Montaner, J., Shear, N., Lucas, A. and Mallal, S. (2007) Genetic characterization of patch test negative patients reporting symptoms after initiation after abacavir. In: 8th International Workshop on Clinical Pharmacology of HIV Therapy, 16 - 18 April 2007, Budapest, Hungary.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Knowles, S., Shear, N., Cavassini, M., Harrigan, R., Montaner, J., Keane, N., Laird, R., Lucas, A. and Mallal, S. (2007) Genetic characterization of patients with MHC class I mediated abacavir hypersensitivity reaction. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Keane, N., Lucas, A., Netto, J., Almeida, C., Martin, A., Marriott, D., Kelleher, A., Phillips, E., Nolan, D. and Mallal, S. (2007) Use of the ELISpot assay to detect abacavir- and nevirapine-induced IFN-g responses in PBMC from HIV-infected patients with abacavir or nevirapine hypersensitivity reactions. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia.

Almeida, C., Mamotte, C., Nolan, D., Martin, A., Hammond, E. and Mallal, S. (2006) Investigation of the sensitivity and specificity of the HLA-B*5701 genotyping assay. In: Pharmacogenetics Meeting in Colds Spring Harbour, 10 - 15 November 2006, New York, U.S.A.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Knowles, S., Shear, N., Harris, N., Montaner, J.S.G. and Mallal, S. (2006) Pharmacogenetics and clinical characteristics of patch test confirmed patients with Abacavir hypersensitivity. In: 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20 - 22 April 2006, Lisbon, Portugal.

Martin, A., Almeida, C., Nolan, D., Cameron, P., James, I., Purcell, T., McCluskey, J., Phillips, E. and Mallal, S. (2005) Abacavir stimulates Hsp70 redistribution in Antigen-presenting cells of patients with hypersensitivity: Association with Type-I alcohol dehydrogenase activity. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Martin, A.M., Almeida, C., Nolan, D., Purcell, A., McCluskey, J., Phillips, E. and Mallal, S. (2005) Both the innate and adaptive immune systems are important in the pathogenesis of abacavir hypersensitivity reaction. In: Gordon Research Conference on Adverse Drug Reactions, 5 - 10 June 2005, New London, CT.

Almeida, C., Martin, A., Nolan, D., Cameron, P., James, I., Mifsud, N., Purcell, A., McCluskey, J. and Mallal, S. (2005) Chronic in vitro abacavir exposure elicits an immunological response in abacavir naive HIV positive individuals. In: 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment, 24 - 27 July 2005, Rio de Janeiro, Brazil.

Martin, A., Nolan, D., Rauch, A., Almeida, C., McKinnon, E. and Mallal, S. (2005) Genetic screening for Abacavir hypersensitivity (ABC-HSR) in the Western Australian cohort: Prospective data and novel diagnostic approaches. In: 17th Annual Conference of the Australasian Society for HIV Medicine (ASHM 2005), 24 - 27 August 2005, Hobart, Tasmania.

Christiansen, F.T., Martin, A.M., Nolan, D.A., Gaudieri, S., Almeida, C., Phillips, E., Cameron, P.U., Moore, C.B., James, I. and Mallal, S.A. (2005) Host MHC influences susceptibility to hypersensitivity reactions to two drugs commonly used in HIV therapy. In: XIX European Immunogenetics & Histocompatibility Conference, 23 - 26 April 2005, Istanbul, Turkey.

Martin, A.M., Almeida, C., Nolan, D., Cameron, P., Purcell, A., Chessman, D., McCluskey, J., Phillips, E. and Mallal, S. (2005) Involvement of metabolic and immune responses in the pathogenesis of Abacavir hypersensitivity reaction. In: 17th Annual Conference of the Australasian Society for HIV Medicine (ASHM 2005), 24 - 27 August 2005, Hobart, Tasmania.

Martin, A., Almeida, C., Purcell, A., McCluskey, J., Phillips, E. and Mallal, S. (2005) Pathogenesis of abacavir hypersensitivity mediated via stimulation of the innate and adaptive immune systems. In: Gordon Conference on Adverse Drug Reactions, 5 - 10 June 2005, Connecticut College, New London, CT.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2005) Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV Cohort. In: 7th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 16 November 2005, Dublin, Ireland.

Martin, A.M., Almeida, C., Nolan, D. and Mallal, S. (2005) TLR2 and CD14 receptors are essential for abacavir induced HSP70 signalling and dendritic cell activation. In: ANS Apoptosis and Immunity 2005, 31 May 2005, Cairns, Australia.

Mallal, S., Almeida, C., Nolan, D. and Martin, A. (2004) Abacavir hypersensitivity as a model for elucidating Class I-restricted drug reactions. In: 7th International Meeting of the International Society for the Study of Xenobiotics, 29 August - 2 September 2004, Vancouver, Canada.

Wong, G., Kaul, R., Shahabi, K., Nolan, D., Mallal, S., Knowles, S., Martin, A., Shear, N. and Phillips, E. (2004) Abacavir hypersensitivity syndrome: Results of clinical, immunological and genetic screening. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

Martin, A.M., Almeida, C., Nolan, D., Gaudieri, S., James, I., Christiansen, F.T., Purcell, A., McCluskey, J. and Mallal, S. (2004) Carriage of HLA-B*5701 and a haplotypic Hsp70-Hom variant is associated with a Class I MHC-restricted hypersensitivity response to abacavir. In: 11th Conference on Retroviruses and Opportunistic Infections, 8 - 11 February 2004, Washington DC, U.S.A.

Martin, A., Cameron, P., Nolan, D., James, I., Keller, J., Phillips, E. and Mallal, S. (2004) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*01 and higher CD4+ T cell counts. In: XV International AIDS Conference, 11 - 16 July 2004, Bangkok, Thailand.

Pace, C., Martin, A., Mamotte, C., Hammond, E., Nolan, D. and Mallal, S. (2003) Effects of HAART on expression (mRNA) of PPAR-gamma, UCP2, UCP1, mitochondrial DNA depletion and proliferation. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Martin, A., Gaudieri, S., Witt, C., Nolan, D., Christiansen, F.T. and Mallal, S. (2003) Mapping of genetic susceptibility to abacavir hypersensitivity. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Christiansen, F.T., Gaudieri, S., Moore, C.B., Martin, A., Nolan, D., James, I.R., McKinnon, E., DeSantis, D., Witt, C.S. and Mallal, S. (2003) The immune response to HIV: The interplay between virus and host genetic factors. In: British Society for Immunology Annual Congress, 2 - 5 December 2003, Harrogate, England.

Mallal, S., Witt, C., Martin, A.M., Masel, G., Moore, C., Sayer, D., Castley, A., Mamotte, C., Nolan, D., James, I. and Christiansen, F.T. (2002) The presence of HLA-B*5701, -DRB1*0701 and -DQ3 is highly predictive of hypersensitivity to the HIV reverse transcriptase inihibitor abacavir. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A.

This list was generated on Thu Oct 30 07:12:39 2014 GMT.