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Journal Article

Strautins, K., Tschochner, M., James, I., Choo, L., Dunn, D., Pedrini, M., Kermode, A., Carroll, W. and Nolan, D. (2014) Combining HLA-DR risk alleles and anti-Epstein-Barr virus antibody profiles to stratify multiple sclerosis risks. Multiple Sclerosis Journal, 20 (3). pp. 286-294.

Rojana-udomsart, A., Mitrpant, C., James, I., Witt, C., Needham, M., Day, T., Kiers, L., Corbett, A., Martinez, P., Wilton, S.D. and Mastaglia, F.L. (2013) Analysis of HLA-DRB3 alleles and supertypical genotypes in the MHC Class II region in sporadic inclusion body myositis. Journal of Neuroimmunology, 254 (1-2). pp. 174-177.

Phillips, E., Bartlett, J.A., Sanne, I., Lederman, M.M., Hinkle, J., Rousseau, F., Dunn, D., Pavlos, R., James, I., Mallal, S.A. and Haas, D.W. (2013) Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 62 (2). e55-e57.

Johnson, L., James, I., Rodrigues, J., Stell, R., Thickbroom, G. and Mastaglia, F. (2013) Clinical and posturographic correlates of falling in Parkinson's disease. Movement Disorders, 28 (9). pp. 1250-1256.

Hertz, T., Oshansky, C., Roddam, P., DeVincenzo, J., Caniza, M., Jojic, N., Mallal, S., Phillips, E., James, I., Thomas, P., Halloran, M. and Corey, L. (2013) HLA targeting efficiency correlates with human T cell response magnitude and with mortality from influenza A infection. The Journal of Immunology, 190 (Supp. 1). 49.21.

Hertz, T., Oshansky, C.M., Roddam, P.L., DeVincenzo, J.P., Caniza, M.A., Jojic, N., Mallal, S., Phillips, E., James, I., Halloran, M.E., Thomas, P.G. and Corey, L. (2013) HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proceedings of the National Academy of Sciences, 110 (33). pp. 13492-13497.

Mastaglia, F.L., Rojana-udomsart, A., James, I., Needham, M., Day, T.J., Kiers, L., Corbett, J.A., Saunders, A.M., Lutz, M.W. and Roses, A.D. (2013) Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. Neuromuscular Disorders, 23 (12). pp. 969-974.

Yuen, E., James, I., Taplin, R. and Ho, G. (2013) Socio-environmental factors affecting water demand in discrete aboriginal communities in Australia. International Journal of Water, 7 (3). pp. 240-258.

Qiu, W., Pham, K., James, I., Nolan, D., Castley, A., Christiansen, F.T., Czarniak, P., Luo, Y., Wu, J., Garlepp, M., Wilton, S., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2013) The influence of non-HLA gene polymorphisms and interactions on disease risk in a Western Australian multiple sclerosis cohort. Journal of Neuroimmunology, 261 (1-2). pp. 92-97.

Nolan, D., Castley, A., Tschochner, M., James, I., Qiu, W., Sayer, D., Christiansen, F.T., Witt, C., Mastaglia, F., Carroll, W. and Kermode, A. (2012) Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk. Neurology, 79 (6). pp. 538-546.

Reeves, K.L., McKinnon, E.J. and James, I.R. (2012) Correction for founder effects in host-viral association studies via principal components. Statistical Applications in Genetics and Molecular Biology, 11 (4).

Rojana-udomsart, A., Bundell, C., James, I., Castley, A., Martinez, P., Christiansen, F., Hollingsworth, P. and Mastaglia, F. (2012) Frequency of autoantibodies and correlation with HLA-DRB1 genotype in sporadic inclusion body myositis (s-IBM): A population control study. Journal of Neuroimmunology, 249 (1-2). pp. 66-70.

Rojana-udomsart, A., Castley, A, James, I., Needham, M., Scott, A., Day, T., Kiers, L., Corbett, A., Sue, C., Martinez, P., Christiansen, F. and Mastaglia, F.L. (2012) G.P.63 High-resolution analysis of HLA-DRB1 alleles and diplotypes in an Australian inclusion body myositis cohort. Neuromuscular Disorders, 22 (9-10). pp. 853-854.

Blais, M.-E., Zhang, Y., Rostron, T., Griffin, H., Taylor, S., Xu, K., Yan, H., Wu, H., James, I., John, M., Dong, T. and Rowland-Jones, S. L. (2012) High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C - Restricted CTL selective pressure associated with an AIDS-protective polymorphism. The Journal of Immunology, 188 (9). pp. 4663-4670.

Keane, N.M., Roberts, S.G., Almeida, C.M., Krishnan, T., Chopra, A., Demaine, E., Laird, R., Tschochner, M., Carlson, J.M., Mallal, S., Heckerman, D., James, I. and John, M. (2012) High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection. Immunology and Cell Biology, 90 (2). pp. 224-234.

Rojana-udomsart, A., James, I., Castley, A., Needham, M., Scott, A., Day, T., Kiers, L., Corbett, A., Sue, C., Witt, C., Martinez, P., Christiansen, F. and Mastaglia, F. (2012) High-resolution HLA-DRB1 genotyping in an Australian inclusion body myositis (s-IBM) cohort: An analysis of disease-associated alleles and diplotypes. Journal of Neuroimmunology, 250 (1-2). pp. 77-82.

Desmond, C.P., Gaudieri, S., James, I.R., Pfafferott, K., Chopra, A., Lau, G.K., Audsley, J., Day, C., Chivers, S., Gordon, A., Revill, P.A., Bowden, S., Ayres, A., Desmond, P.V., Thompson, A.J., Roberts, S. K., Locarnini, S.A., Mallal, S.A. and Lewin, S.R. (2012) Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease. Journal of Virology, 86 (2). pp. 1181-1192.

Rajasuriar, R., Booth, D.R., Gouillou, M., Spelman, T., James, I., Solomon, A., Chua, K., Stewart, G., Deeks, S., Bangsberg, D.R., Muzoora, C., Cameron, P.U., Hunt, P., Martin, J. and Lewin, S.R. (2012) The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART. Genes and Immunity, 13 (1). pp. 83-93.

Pfafferott, K., Gaudieri, S., Ulsenheimer, A., James, I., Heeg, M., Nolan, D., John, M., Rauch, A., Mallal, S., Lucas, A.D., Klenerman, P., Diepolder, H.M. and Lucas, M. (2011) Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity. PLoS ONE, 6 (2). e16797.

Merani, S., Petrovic, D., James, I., Chopra, A., Cooper, D., Freitas, E., Rauch, A., di Iulio, J., John, M., Lucas, M., Fitzmaurice, K., McKiernan, S., Norris, S., Kelleher, D., Klenerman, P. and Gaudieri, S. (2011) Effect of immune pressure on hepatitis C virus evolution: Insights from a single-source outbreak. Hepatology, 53 (2). pp. 396-405.

Dong, T., Zhang, Y., Xu, K. Y., Yan, H., James, I., Peng, Y., Blais, M.-E., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W. Y., Rostron, T., Li, N., Mao, Y., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. L. (2011) Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Blood, 118 (1). pp. 98-106.

Qiu, W., James, I., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2011) HLA-DR allele polymorphism and multiple sclerosis in Chinese populations: a meta-analysis. Multiple Sclerosis, 17 (4). pp. 382-388.

Hertz, T., Nolan, D., James, I., John, M., Gaudieri, S., Phillips, E.J., Huang, J.C., Riadi, G., Mallal, S. and Jojic, N. (2011) Mapping the Landscape of Host-Pathogen Coevolution: HLA Class I Binding and Its Relationship with Evolutionary Conservation in Human and Viral Proteins. Journal of Virology, 85 (3). pp. 1310-1321.

Qiu, W., Raven, S., James, I., Luo, Y., Wu, J., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2011) Spinal cord involvement in multiple sclerosis: A correlative MRI and high-resolution HLA-DRB1 genotyping study. Journal of the Neurological Sciences, 300 (1-2). pp. 114-119.

Morahan, G., Mehta, M., James, I., Chen, W.-M., Akolkar, B., Erlich, H. A., Hilner, J. E., Julier, C., Nerup, J., Nierras, C., Pociot, F., Todd, J. A. and Rich, S. S. (2011) Tests for genetic interactions in Type 1 Diabetes: Linkage and stratification analyses of 4,422 affected Sib-Pairs. Diabetes, 60 (3). pp. 1030-1040.

John, M., Heckerman, D., James, I., Park, L.P., Carlson, J.M., Chopra, A., Gaudieri, S., Nolan, D., Haas, D.W., Riddler, S.A., Haubrich, R. and Mallal, S. (2010) Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. The Journal of Immunology, 184 (8). pp. 4368-4377.

Qiu, W., Wu, J-S, Castley, A., James, I., Joseph, J., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia. Journal of Clinical Neuroscience, 17 (8). pp. 1009-1013.

Wu, J-S, James, I., Qiu, W., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) HLA-DRB1 allele heterogeneity influences multiple sclerosis severity as well as risk in Western Australia. Journal of Neuroimmunology, 219 (1-2). pp. 109-113.

Wu, J.S., James, I., Wei, Q., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution genotyping study. Multiple Sclerosis, 16 (5). pp. 526-532.

Qiu, W., Bundell, C., Wu, J.-S., Castley, A., James, I., Hollingsworth, P., Christiansen, F., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Low level of systemic autoimmunity in Western Australian multiple sclerosis patients. Multiple Sclerosis, 16 (3). pp. 351-354.

Wu, J-S, Qiu, W., Castley, A., James, I., Mastaglia, F.L., Christiansen, F.T, Carroll, W.M, Joseph, J. and Kermode, A.G. (2010) Modifying effects of HLA-DRB1 allele interactions on age at onset of multiple sclerosis in Western Australia. Multiple Sclerosis, 16 (1). pp. 15-20.

Wu, J-S, Qiu, W., Castley, A., James, I., Joseph, J., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort. Journal of the Neurological Sciences, 288 (1-2). pp. 63-67.

McKinnon, E., Morahan, G., Nolan, D. and James, I. (2009) Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 92-100.

Rauch, A., James, I., Pfafferott, K., Nolan, D., Klenerman, P., Cheng, W., Mollison, L., McCaughan, G., Shackel, N., Jeffrey, G.P., Baker, R., Freitas, E., Humphreys, I., Furrer, H., Günthard, H.F., Hirschel, B., Mallal, S., John, M., Lucas, M., Barnes, E. and Gaudieri, S. (2009) Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure. Hepatology, 50 (4). pp. 1017-1029.

Morahan, G., Mehta, M., McKinnon, E. and James, I. (2009) Effect of linkage status of affected sib-pairs on the search for novel type 1 diabetes susceptibility genes in the HLA complex. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 67-73.

Tschochner, M., Chopra, A., Maiden, T.M., Ahmad, I.F., James, I., Furrer, H., Günthard, H., Mallal, S., Rauch, A. and John, M. (2009) Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance. Antiviral Therapy, 14 (7). pp. 953-964.

Morahan, G., McKinnon, E., Berry, J., Browning, B., Julier, C., Pociot, F. and James, I. (2009) Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium. Genes and Immunity, 10 . S64-S68.

Gaudieri, S., Rauch, A., Pfafferott, K., Barnes, E., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G.P., Mollison, L., Baker, R., Furrer, H., Günthard, H.F., Freitas, E., Humphreys, I., Klenerman, P., Mallal, S., James, I., Roberts, S., Nolan, D. and Lucas, M. (2009) Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy. Hepatology, 49 (4). pp. 1069-1082.

Price, P. and James, I. (2009) IL1A alleles associate with a virological response to antiretroviral therapy in HIV patients beginning therapy with advanced disease. AIDS, 23 (9). pp. 1173-1176.

James, I., McKinnon, E., Gaudieri, S. and Morahan, G. (2009) Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 101-107.

Keane, N.M., Roberts, S.G., Laird, R., Chopra, A., Krishnan, T., Almeida, C.M., Bronke, C., Mallal, S., James, I. and John, M. (2009) P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy. Retrovirology, 6 (Suppl 3, 22 October 2009). P128.

Dong, T., Zhang, Y., Xu, K., Yan, H., James, I., Peng, Y., Blais, M., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W., Zhao, C., Li, N., Mao, Y., Rostron, T., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. (2009) P20-19 LB. Extensive HLA-driven viral diversity following a single-source HIV-1 outbreak in rural China. Retrovirology, 6 (Suppl 3). P423.

Mastaglia, F.L., Needham, M., Scott, A., James, I., Zilko, P., Day, T., Kiers, L., Corbett, A., Witt, C.S., Allcock, R., Laing, N., Garlepp, M. and Christiansen, F.T. (2009) Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype. Neuromuscular Disorders, 19 (11). pp. 763-765.

Needham, M., Hooper, A., James, I., van Bockxmeer, F., Corbett, A., Day, T., Garlepp, M.J. and Mastaglia, F.L. (2008) Apolipoprotein ε alleles in sporadic inclusion body myositis: A reappraisal. Neuromuscular Disorders, 18 (2). pp. 150-152.

Almeida, C.M., Martin, A.M., Nolan, D., Lucas, A., Cameron, P.U., James, I., Phillips, E. and Mallal, S. (2008) Cytokine profiling in abacavir hypersensitivity patients. Antiviral Therapy, 13 (2). pp. 281-288.

Rauch, A., Nolan, D., Furrer, H., McKinnon, E., John, M., Mallal, S., Gaudieri, S., Günthard, H.F., Schmid, P., Battegay, M., Hirschel, B., Telenti, A., James, I. and Swiss HIV Cohort Study, . (2008) HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy. Clinical Infectious Diseases, 46 (12). pp. 1921-1925.

Kulski, J.K., Shigenari, A., Shiina, T., Ota, M., Hosomichi, K., James, I. and Inoko, H. (2008) Human endogenous retrovirus (HERVK9) structural polymorphism with haplotypic HLA-A allelic associations. Genetics, 180 (1). pp. 445-457.

Tan, D.B.A., Yong, Y.K., Tan, H.Y., Kamarulzaman, A., Tan, L.H., Lim, A., James, I., French, M. and Price, P. (2008) Immunological profiles of immune restoration disease presenting as mycobacterial lymphadenitis and cryptococcal meningitis. HIV Medicine, 9 (5). pp. 307-316.

Rauch, A., Gaudieri, S., Evison, J., Nolan, D., Cavassini, M., Weber, R., James, I. and Furrer, H. (2008) Low current and nadir CD4+ T-cell counts are associated with higher hepatitis C virus RNA levels in the Swiss HIV cohort study. Antiviral Therapy, 13 (3). pp. 455-60.

Price, P., Fernandez, S., Tan, D.B.A., James, I.R., Keane, N.M. and French, M.A. (2008) Nadir CD4 T-cell counts continue to influence interferon-γ responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency. JAIDS Journal of Acquired Immune Deficiency Syndromes, 49 (4). pp. 462-464.

Needham, M., James, I., Corbett, A., Day, T., Christiansen, F., Phillips, B. and Mastaglia, F.L. (2008) Sporadic inclusion body myositis: Phenotypic variability and influence of HLA-DR3 in a cohort of 57 Australian cases. Journal of Neurology, Neurosurgery & Psychiatry, 79 (9). pp. 1056-1060.

Harari, A., Cellerai, C., Enders, F.B., Kostler, J., Codarri, L., Tapia, G., Boyman, O., Castro, E., Gaudieri, S., James, I., John, M., Wagner, R., Mallal, S. and Pantaleo, G. (2007) Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proceedings of the National Academy of Sciences, 104 (41). pp. 16233-16238.

Pocathikorn, A., Taylor, R.R., James, I. and Mamotte, C.D.S. (2007) LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism. Journal of Nutrition, 137 (9). pp. 2062-2067.

Lim, A., Tan, D.B.A., Price, P., Kamarulzaman, A., Tan, H.Y., James, I. and French, M.A. (2007) Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy. AIDS, 21 (12). pp. 1525-1534.

Martin, A., Almeida, C.M., Cameron, P.U., Purcell, Anthony W, Nolan, D., James, I., McCluskey, J., Phillips, E.J., Landay, Alan and Mallal, S. (2007) Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS, 21 (10). pp. 1233-1244.

Flatau, P., James, I., Watson, R., Wood, G. and Hendershott, P.H. (2007) Leaving the parental home in Australia over the generations: Evidence from the Household, Income and Labour Dynamics in Australia (Hilda) Survey. Journal of Population Research, 24 (1). pp. 51-71.

Gaudieri, S., Rauch, A., Park, L.P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Naidoo, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2007) Erratum: Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection (Journal of Virology (2006) 80, 22, (11094-11104)). Journal of Virology, 81 (16). pp. 8846-8848.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2007) Erratum: Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation (Journal of Virology (2006) 80, 18, (9259-9269)). Journal of Virology, 81 (16). pp. 8843-8845.

Flatau, P., James, I., Watson, R., Wood, G. and Hendershott, P.H. (2007) Leaving the parental home in Australia over the generations: evidence from the Household, Income and Labour Dynamics in Australia (Hilda) Survey. Journal of Population Research, 24 (1). pp. 51-71.

Hammond, E., Shaw, K., Carnley, B., P'ng, S., James, I. and Herrmann, R. (2007) Quantitative determination of JAK2 V617F by TaqMan: An absolute measure of averaged copies per cell that may be associated with the different types of myeloproliferative disorders. The Journal of Molecular Diagnostics, 9 (2). pp. 242-248.

Fernandez, S., Rosenow, A.A., James, I.R., Roberts, S.G., Nolan, R.C., French, M.A. and Price, P. (2006) Recovery of CD4+ T Cells in HIV Patients With a Stable Virologic Response to Antiretroviral Therapy Is Associated With Polymorphisms of Interleukin-6 and Central Major Histocompatibility Complex Genes. JAIDS Journal of Acquired Immune Deficiency Syndromes, 41 (1). pp. 1-5.

Gaudieri, S., Rauch, A., Park, L.P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Naidoo, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2006) Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection. Journal of Virology, 80 (22). pp. 11094-11104.

Burgess, K., Price, P., James, I.R., Stone, S.F., Keane, N.M., Lim, A.Y.F., Warmington, J.R. and French, M.A. (2006) Interferon-Gamma responses to candida recover slowly or remain low in immunodeficient HIV patients responding to ART. Journal of Clinical Immunology, 26 (2). pp. 160-167.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2006) Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation. Journal of Virology, 80 (18). pp. 9259-9269.

Cherry, C.L., Nolan, D., James, I.R., McKinnon, E.J., Mallal, S.A., Gahan, M.E., Lal, L., McArthur, J.C. and Wesselingh, S.L. (2006) Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-Infected individuals. JAIDS Journal of Acquired Immune Deficiency Syndromes, 42 (4). pp. 435-440.

Gruters, R.A., Osterhaus, A.D.M.E., Nolan, D., James, I. and Mallal, S. (2005) HIV and smallpox. Science, 308 (5726). 1258b-1259b.

Nolan, D., James, I. and Mallal, S. (2005) HIV/AIDS: HIV: Experiencing the pressures of modern life. Science, 307 (5714). pp. 1422-1424.

John, M., Moore, C.B., James, I.R. and Mallal, S.A. (2005) Interactive selective pressures of HLA-restricted immune responses and antiretroviral drugs on HIV-1. Antiviral Therapy, 10 . pp. 551-555.

Martin, A.M., Nolan, D., James, I., Cameron, P., Keller, J., Moore, C., Phillips, E., Christiansen, F.T. and Mallal, S. (2005) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS, 19 (1). pp. 97-99.

Redgrave, B.E., Stone, S.F., French, M.A.H., Krueger, R., James, I.R. and Price, P. (2005) The effect of combination antiretroviral therapy on CD5 B- cells, B-cell activation and hypergammaglobulinaemia in HIV-1-infected patients. HIV Medicine, 6 (5). pp. 307-312.

Windsor, L., Morahan, G., Huang, D., McCann, V., Jones, T., James, I., Christiansen, F.T. and Price, P. (2004) Alleles of the IL12B 3′UTR associate with late onset of type 1 diabetes. Human Immunology, 65 (12). pp. 1432-1436.

Price, P., James, I., Fernandez, S. and French, M.A. (2004) Alleles of the gene encoding IL-1?? may predict control of plasma viraemia in HIV-1 patients on highly active antiretroviral therapy. AIDS, 18 (11). pp. 1495-1501.

Kiepiela, P., Leslie, A.J., Honeyborne, I., Ramduth, D., Thobakgale, C., Chetty, S., Rathnavalu, P., Moore, C.B., Pfafferott, K.J., Hilton, L., Zimbwa, P., Moore, S., Allen, T., Brander, C., Addo, M.M., Altfeld, M., James, I., Mallal, S., Bunce, M., Barber, L.D., Szinger, J., Day, C., Klenerman, P., Mullins, J., Korber, B., Coovadia, H.M., Walker, B.D. and Goulder, P.J.R. (2004) Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature, 432 (7018). pp. 769-775.

Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., James, I., Phillips, E. and Mallal, S. (2004) Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences, 101 (12). pp. 4180-4185.

Hammond, E., Nolan, D., James, I., Metcalf, C. and Mallal, S. (2004) Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6-12 months of commencing nucleoside reverse transcriptase inhibitor therapy. AIDS, 18 (5). pp. 815-817.

Keane, N.M., Price, P., Lee, S., Almeida, C.A., Stone, S.F., James, I. and French, M.A. (2004) Restoration of CD4 T-cell responses to cytomegalovirus is short-lived in severely immunodeficient HIV-infected patients responding to highly active antiretroviral therapy. HIV Medicine, 5 (6). pp. 407-414.

Nolan, D., Hammond, E., James, I., McKinnon, E. and Mallal, S. (2003) Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antiviral Therapy, 8 (6). pp. 617-626.

Christiansen, F.T., Gaudieri, S., Santis, D.D., Moore, C.B., Witt, C.S., James, I.R. and Mallal, S.A. (2003) NK receptor genes are predictors of HIV progression. Human Immunology, 64 (10). S12.

John, M., McKinnon, E.J., James, I.R., Nolan, D., Herrmann, S.E., Moore, C.B., White, A.J. and Mallal, S.A. (2003) Randomised, controlled, 48-week study of switching stavudine and/or protease inhibitors to Combavir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33 (1). pp. 29-34.

Nolan, D., Moore, C., Castley, A., Sayer, D., Marmotte, C., John, M., James, I. and Mallal, S. (2003) Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS, 17 (1). pp. 121-123.

McKinnon, E.J., James, I.R., John, M. and Mallal, S.A. (2003) Viral load detectability profiles for HIV infection. Statistics in Medicine, 22 (3). pp. 385-396.

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A.M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F.T. (2002) Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. The Lancet, 359 (9308). pp. 727-732.

Doherty, D.A., James, I.R. and Newnham, J.P. (2002) Estimation of the Doppler ultrasound maximal umbilical waveform envelope: I. Estimation method. Ultrasound in Medicine & Biology, 28 (10). pp. 1251-1259.

Doherty, D.A., James, I.R. and Newnham, J.P. (2002) Estimation of the Doppler ultrasound umbilical maximal waveform envelope: II. Prediction of fetal distress. Ultrasound in Medicine & Biology, 28 (10). pp. 1261-1270.

Moore, C.B., John, M., James, I.R., Christiansen, F.T., Witt, C.S. and Mallal, S. (2002) Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level. Science, 296 (5572). pp. 1439-1443.

Christiansen, F.T., John, M., James, I.R., Witt, C.S. and Mallal, S.A. (2002) Immune escape mutations in HIV-1 sequence: the influence of HLA class I and II alleles in a host population on viral evolution. Human Immunology, 63 (10). S35.

Vu, H.T.V., Segal, M.R., Knuiman, M.W. and James, I.R. (2001) Asymptotic and small sample statistical properties of random frailty variance estimates for shared gamma frailty models. Communications in Statistics - Simulation and Computation, 30 (3). pp. 581-595.

John, M., Moore, C.B., James, I.R., Nolan, D., Upton, R.P., McKinnon, E.J. and Mallal, S.A. (2001) Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS, 15 (6). pp. 717-723.

de Meijer, R.J., James, I.R., Jennings, P.J. and Koeyers, J.E. (2001) Cluster analysis of radionuclide concentrations in beach sand. Applied Radiation and Isotopes, 54 (3). pp. 535-542.

Nolan, D., Upton, R., McKinnon, E., John, M., James, I., Adler, B., Roff, G., Vasikaran, S. and Mallal, S. (2001) Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir. AIDS, 15 (10). pp. 1275-1280.

Mallal, S.A., John, M., Moore, C.B., James, I.R. and McKinnon, E.J. (2000) Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS, 14 (10). pp. 1309-1316.

French, M.A., Lenzo, N., John, M., Mallal, S.A., McKinnon, E.J., James, I.R., Price, P., Flexman, J.P. and Tay-Kearney, M-L (2000) Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Medicine, 1 (2). pp. 107-115.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of bone mineral density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat: With an additional independent effect of indinavir therapy to increase BMD. Antiviral Therapy, 5 (Supp. 5).

Segal, M.R., Neuhaus, J.M. and James, I.R. (1997) Dependence estimation for marginal models of multivariate survival data. Lifetime Data Analysis, 3 (3). pp. 251-268.

Gales, N.J., Williamson, P., Higgins, L.V., Blackberry, M.A. and James, I. (1997) Evidence for a prolonged postimplantation period in the Australian sea lion (Neophoca cinerea). Journal of Reproduction and Fertility, 111 (2). pp. 159-163.

James, I.R., Hogan, S.J. and Mallal, S.A. (1995) Analysis of doubly censored data and the HIV incubation period distribution in Western Australia. Australian Journal of Statistics, 37 (3). pp. 299-312.

Segal, M.R., James, I.R., French, M.A.H. and Mallal, S.A. (1995) Statistical issues in the evaluation of markers of HIV progression. International Statistical Review/ Revue Internationale de Statistique , 63 (2). pp. 179-197.

James, I.R. and Tanner, M.A. (1995) A note on the analysis of censored regression data by multiple imputation. Biometrics, 51 (1). pp. 358-362.

Mallal, S.A., James, I.R. and French, M.A.H. (1994) Detection of subclinical Mycobacterium avium intracellulare complex infection in immunodeficient HIV-infected patients treated with zidovudine. AIDS, 8 (9). pp. 1263-1269.

Mallal, S., Martinez, O.P., French, M.A.H., James, I.R. and Dawkins, R.L. (1994) Severity and outcome of Pneumocystis Carinii Pneumonia (PCP) in patients of known and unknown HIV status. JAIDS Journal of Acquired Immune Deficiency Syndromes, 7 (2). pp. 148-153.

Halse, S., James, I., Fitzgerald, P., Diepeveen, D. and Munro, D. (1993) Survival and hunting mortality of Pacific black ducks and grey teal. Journal of Wildlife Management, 57 (1). pp. 42-48.

O'Leary, P.C., Boyne, P., Atkinson, G., Mileham, K.-J. and James, I. (1992) Longitudinal study of serum thyroid hormone levels during normal pregnancy. International Journal of Gynecology & Obstetrics, 38 (3). pp. 171-179.

James, I.R. (1991) Estimation of von Bertalanffy growth curve parameters from recapture data. Biometrics, 47 (4). pp. 1519-1530.

O'Leary, P., Boyne, P., Flett, P., Beilby, J. and James, I. (1991) Longitudinal assessment of changes in reproductive hormones during normal pregnancy. Clinical Chemistry, 37 (5). pp. 667-672.

Newnham, J.P., Patterson, L., James, I. and Stanley, E.R. (1990) Effects of maternal cigarette smoking on ultrasonic measurements of fetal growth and on Doppler flow velocity waveforms. Early Human Development, 24 (1). pp. 23-36.

Newnham, J.P., Patterson, L.L., James, I. and Diepeveen, D. (1990) An evaluation of the efficacy of Doppler flow velocity waveform analysis as a screening test in pregnancy. American Journal of Obstetrics and Gynecology, 162 (2). pp. 403-410.

Conference Paper

James, I., McKinnon, E. and Mallal, S. (2002) Comparison of rates of progression in HIV observational cohorts. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

McKinnon, E., John, M., James, I. and Mallal, S. (2002) Effect of baseline CD4 on virological response to first HAART. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

John, M., Moore, C., James, I. and Mallal, S. (2002) Immune escape mutations in HIV-1 at a population level. In: GSK Observational HIV Cohorts Meeting, 6 - 7 November 2002, Boston, U.S.A

John, M., Moore, C.B., James, I.R., Christiansen, F.T., Witt, C.S. and Mallal, S.A. (2002) Immune escape mutations in HIV-1 sequence: The influence of HLA class I and II alleles in a host population on viral evolution. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A

Christiansen, F.T., John, M., James, I., Witt, C. and Mallal, S. (2002) Immune escape mutations in HIV-1 sequence: the influence of HLA class I and II alleles in a host population on viral evolution. In: 28th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 19 - 23 October 2002, Nashville, TN

Christiansen, F.T., Gaudieri, S., De Santis, D., Witt, C.S., James, I.R. and Mallal, S. (2002) NK receptor genes are predictors of HIV progression. In: 28th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 19 - 23 October 2002, Nashville, TN

McKinnon, E., James, I. and Mallal, S. (2002) Progessive matching in HIV observational studies. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

Nolan, D., James, I., McKinnon, E. and Mallal, S. (2002) Stavudine, zidovudine and protease inhibitor therapy effects on subcutaneous leg fat wasting in HIV-infected males. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Nolan, D., Moore, C., Castley, A., Sayer, D., Mamotte, C., John, M., James, I. and Mallal, S. (2002) Tumour necrosis factor alpha gene - 238G/A promoter polymorphism associated with more rapid onset of lipodystrophy. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F. (2002) The presence of HLA-B*5701, -DRB1*0701, and -DQ3 Is highly predictive of hypersensitivity to the HIV reverse transcriptase inhibitor abacavir. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A

John, M., Moore, C., James, I. and Mallal, S. (2001) Characteristic Non-synonymous mutation in HIV reverse transcriptase sequence encoding an HLA-B7-restricted CTL epitope is associated with increased viral load. In: 8th Conference on Retroviruses and Opportunistic Infections , 4 - 8 February 2001, Chicago, IL

James, I., Moore, C., John, M., Nolan, D., McKinnon, E. and Mallal, S. (2001) Effect of HAART on subcutaneous fat in HIV-infected males: A longitudinal study. In: 5th International Workshop on HIV Observational Databases, 26 - 27 April 2001, Monte Carlo

John, M., Moore, C., James, I. and Mallal, S. (2001) Selection of immune escape mutation in HIV-1 is evident at a population level. In: 13th Annual Conference of the Australian Society for HIV Medicine, 4 - 7 October 2001, Melbourne, VIC

Mallal, S., Moore, C., John, M., James, I., Nolan, D., Sayer, D. and Witt, C. (2000) Characteristic changes in HIV reverse trancriptase sequence at sites encoding known CTL epitopes at a population level. In: XIII International AIDS Conference, 9 - 14 July 2000, Durban, South Africa

Moore, C., John, M., James, I. and Mallal, S. (2000) Characteristic mutations in HIV-1 reverse transcriptase sequence encoding HLA class I restricted CTL epitopes: Evidence of HIV-1 CTL escape at a population level. In: 24th Annual Australasian and South East Asian Tissue Typing Association Conference, 30 November - 3 December 2000, Perth, Western Australia

John, M., Moore, C., James, I., Nolan, D., Upton, R. and Mallal, S. (2000) Predictors of lactic acidemia in the WA HIV cohort. In: Fourth International Cohorts Meeting on HIV Observational Databases, 30 - 31 March 2000, Marbella, Spain

John, M., Moore, C., James, I., Nolan, D. and Mallal, S. (2000) Predictors of response to antiretroviral therapy in the WA HIV cohort. In: Fourth International Cohorts Meeting on HIV Observational Databases, 30 - 31 March 2000, Marbella, Spain

White, A.J., John, M., Moore, C., James, I.R., Nolan, D. and Mallal, S.A. (2000) Raised lactate levels are common and may be predictive of subcutaneous fat wasting. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada

John, M., Moore, C., James, I., McKinnon, E. and Mallal, S. (2000) Relative contribution of NRTIs, NNRTIs and PIs to chronic asymptomatic lactic acidaemia in HIV infected patients. In: European Symposium on Lipodyctrophy and HIV Infection, 24 - 25 March 2000, Marrakesh, Morocco

Mallal, S., Moore, C., James, I.R., Sayer, D., Witt, C., Christiansen, F.T. and French, M.A. (1999) Class I MHC associated non-synonymous mutations of HIV sequences - possible selection of CTL escape mutations at a population level? In: A Keystone Symposia HIV Vaccine Development: Opportunities and Challenges and AIDS Pathogenesis, 7 - 13 January 1999, Colorado, U.S.A

Mallal, S., John, M., Moore, C., James, I. and McKinnon, E. (1999) Protease inhibitors and nucleoside analogue reverse transcriptase inhibitors interact to cause subcutaneous fat wasting in patients with HIV infection. In: 7th European Conference on Clinical Aspects and Treatment of HIV-Infection , 23 - 27 October 1999, Lisbon, Portugal

Mallal, S., James, I.R., Koenig, A. and French, M.A.H. (1995) Impact of anti-retroviral therapy and pneumocystis carinii pneumonia prophylaxis on the pattern of AIDS illnesses and AIDS survival in the Western Australian HIV Cohort Study: 1983 - 1992. In: Annual Meeting of the Australasian Society for HIV Medicine (ASHM), 16 - 19 November 1995, Coolum, Australia

Conference Item

Shasha, D., Meseret, Y., Chopra, A., Cooper, D., James, I., Herrmann, S., Wolday, D., Maayan, S., Mallal, S. and John, M. (2012) Unique footprints of HLA class I on clade C HIV-1 in a cohort of Ethiopian patients. In: 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012), 5 - 8 March, Seattle, Washington, USA.

Hertz, T., Nolan, D., James, I., John, M., Gaudieri, S., Phillips, E., Huang, J., Riadi, G., Mallal, S. and Jojic, N. (2011) HLA class I binding and its relationship with evolutionary conservation in human proteins and viral proteomes. In: Keystone HIV Evolution Genomics & Pathogenesis, 20 - 25 March 2011, Whistler, British Columbia, Canada.

James, I. (2010) Correlation estimation with bivariate censored data via alternating regressions. In: ASC 2010 Australian Statistical Conference Statistics in the West: Understanding our World., 6 - 10 December, Fremantle, Western Australia.

Gaudieri, S., Rauch, A., James, I., Pfafferott, K., Baker, R., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G., Mollinson, L., Mallal, S., Furrer, H., Günthard, H., Hirschel, B., Klenerman, P., Nolan, D., John, M. and Lucas, M. (2009) Co-localisation of hepatitis C virus drug-resistant mutations and immune-driven adaptations: Relevance to therapy outcome. In: 19th Annual Combined Biological Sciences Meeting 2009, 28 August 2009, Perth, Western Australia.

Gaudieri, S., Rauch, A., James, I., Pfafferott, K., Cheng, W., McCaughan, G., Jeffrey, G., Mollison, L., Furrer, H., Günthard, H., Hirschel, B., Klenerman, P., Mallal, S., Nolan, D., John, M. and Lucas, M. (2009) Divergent adaptation of Hepatitis C virus genotypes to HLA-restricted immune pressure: relevance to HCV infection and vaccine design. In: 16th International Symposium on Hepatitis C Virus & Related Viruses, 3 - 7 October 2009, Nice, France.

Pfafferott, K., Gaudieri, S., Ulsenheimer, A., John, M., James, I., Heeg, M., Nolan, D., Rauch, A., Lucas, A., Klenerman, P., Diepolder, H.M. and Lucas, M. (2009) Divergent pattern of viral evolution and escape dynamics in acute and early HCV and HIV infection. In: Australasian Virology Group Meeting, 13 - 17 December 2009, Mantra Erskine Resort, Lorne, VIC.

Tschochner, M., James , I., Almeida, C., Keane, N., Roberts, S., Bronke, C., Chopra, A., Maiden, T., Ahmad, I., Gaudieri, S., Mallal, S., Rauch, A., John, M., Furrer, H. and Günthard, H. (2009) Effects of HIV-1 immune selection on susceptability to integrase inhibitor resistance. In: 12th European AIDS Conference (EACS) 2009, 11 - 14 November 2009, Cologne, Germany.

Dong, T., Zhang, Y., Xu, K., Yan, H., James, I., Peng, Y., Blais, M., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W., Zhoo, C., Li, N., Mao, Y., Rostron, T., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. (2009) Extensive HLA-driven viral diversity following a single-source HIV-1 outbreak in rural China. In: AIDS Vaccine 2009, 19 - 22 October 2009, Paris, France.

Desmond, C.P., Gaudieri, S., James, I., Pfafferott, K., Chopra, A., Lau, G.K., Locarnini, S.A., Revill, P.A., Day, C.F., Chivers, S., Gordon, A., Bowden, S., Ayres, A., Desmond, P.V., Thompson, A.J., Roberts, S.K., Mallal, S. and Lewin, S.R. (2009) Identification of novel hepatitis B virus (HBV) T-cell epitopes and escape mutations in Asian individuals with chronic HBV infection using a population based approach. In: 60th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2009, 30 October - 3 November 2009, Boston, U.S.A.

Keane, N., Roberts, S., Laird, R., Chopra, A., Krishnan, T., Almeida, C., Bronke, C., Mallal, S., James, I. and John, M. (2009) P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy. In: AIDS Vaccine 2009, 19 - 22 October 2009, Paris, France.

Mallal, S., Hertz, T., John, M., Gaudieri, S. and James, I. (2008) Co-evolution of viruses and their human host: What it might teach us? In: Perth Immunology Group Meeting, 9 - 10 October 2008, Perth Western Australia.

Phillips, E., Nolan, D., Thorborn, D., Schaefer, M., Laird, R., Rauch, A., Rachlis, A., Shear, N., Knowles, S., Hughes, A., Montaner, J., James, I. and Mallal, S. (2008) Genetic factors predicting abacavir hypersensitivity and tolerance in HLA-B*5701 positive individuals. In: 3rd International Drug Hypersensitivity Conference, 11 - 13 April 2008, Paris, France.

Nolan, D., Thorborn, D., Shaefer, M., Laird, R., Montaner, M., Hughes, A., James, I., Mallal, S. and Phillips, E. (2008) Genetic factors predicting abacavir hypersensitivty and tolerance in HLA-B*5701 positive individuals: Combined analysis from PREDICT-1, SHAPE and a multinational study. In: 15th Conference on Retroviruses and Opportunistic Infections (CROI), 3 - 6 February 2008, Boston, U.S.A.

McKinnon, E., John, M., Herrmann, S.E. and James, I. (2007) Models and analysis of point-inflated data in a study of markers of HAART efficacy. In: 11th International Workshop on HIV Observational Databases, 22 - 25 March, Monte Carlo.

Harari, A., Cellerai, C., Kostler, J., Gaudieri, S., James, I., John, M., Wagner, R., Mallal, S. and Pantaleo, G. (2007) Relationship between HLA Genotype and the functional profile of Antigen-specific CD8 T cells. In: 14th Conference on Retroviruses and Opportunistic Infections, 25 - 28 February 2007, Los Angeles, U.S.A.

John, M., Heckerman, D., Park, L., Gaudieri, S., James, I., Nolan, D., Chopra, A., Riddler, S., Haubrich, R. and Mallal, S. (2007) Strong genome-wide HLA associated selection in HIV-1. In: 31st Annual Scientific Meeting of the Australasian and South East Asian Tissue Typing Association (ASEATTA) 2007, 14 - 16 November 2007, Fremantle, WA.

Gaudieri, S., Rauch, A., Naidoo, K., Park, P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2006) Evidence of viral adaptation to HLA Class I-restricted immune pressure in chronic Hepatitis C virus infection. In: 13th International Meeting on Hepatitis C Virus & Related Viruses, 27 - 31 August, Cairns, Australia.

Martin, A., Almeida, C., Nolan, D., Cameron, P., James, I., Purcell, T., McCluskey, J., Phillips, E. and Mallal, S. (2005) Abacavir stimulates Hsp70 redistribution in Antigen-presenting cells of patients with hypersensitivity: Association with Type-I alcohol dehydrogenase activity. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

James, I., McKinnon, E., John, M. and Mallal, S. (2005) Association of HLA-Bw4 with post-HAART outcomes. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

Almeida, C., Martin, A., Nolan, D., Cameron, P., James, I., Mifsud, N., Purcell, A., McCluskey, J. and Mallal, S. (2005) Chronic in vitro abacavir exposure elicits an immunological response in abacavir naive HIV positive individuals. In: 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment, 24 - 27 July 2005, Rio de Janeiro, Brazil.

McKinnon, E., Lucas, M., French, M., James, I. and Mallal, S. (2005) Differential influence of age on CD4 T-cell response to HAART. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

McKinnon, E., James, I., Lucas, M. and Mallal, S. (2005) Differential influence of age on maximal immune response to HAART. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

Christiansen, F.T., Martin, A.M., Nolan, D.A., Gaudieri, S., Almeida, C., Phillips, E., Cameron, P.U., Moore, C.B., James, I. and Mallal, S.A. (2005) Host MHC influences susceptibility to hypersensitivity reactions to two drugs commonly used in HIV therapy. In: XIX European Immunogenetics & Histocompatibility Conference, 23 - 26 April 2005, Istanbul, Turkey.

McKinnon, E., James, I. and Mallal, S. (2004) Assessment of virological control in patients with HIV undergoing HAART. In: 8th International Workshop on HIV Observational Databases, 25 - 28 March 2004, Montreux, Switzerland.

Martin, A.M., Almeida, C., Nolan, D., Gaudieri, S., James, I., Christiansen, F.T., Purcell, A., McCluskey, J. and Mallal, S. (2004) Carriage of HLA-B*5701 and a haplotypic Hsp70-Hom variant is associated with a Class I MHC-restricted hypersensitivity response to abacavir. In: 11th Conference on Retroviruses and Opportunistic Infections, 8 - 11 February 2004, Washington DC, U.S.A.

Hammond, E., Nolan, D., James, I., McKinnon, E. and Mallal, S. (2004) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipoatrophy in HIV infected patients: A model of drug induced mitochondrial toxicity. In: Mitochodrial Medicine 2004, 4 - 8 August 2004, Pittsburgh, PA.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2004) Differential effects of nucleoside reverse transcriptase inhibitor (NRTI) regimens on adipocyte mitochondrial DNA depletion in HIV-infected patients. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

Martin, A., Cameron, P., Nolan, D., James, I., Keller, J., Phillips, E. and Mallal, S. (2004) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*01 and higher CD4+ T cell counts. In: XV International AIDS Conference, 11 - 16 July 2004, Bangkok, Thailand.

Herrmann, S., Hyland, N., Coombs, A., Turner, K., Duncan, F., McKinnon, E., James, I., Martinez, O.P., French, M. and Mallal, S. (2003) Adherence to antiretroviral therapy in the WA HIV Cohort. In: 15th Annual Conference of the Australian Society for HIV Medicine, 22 - 25 October, Cairns, Australia.

James, I., Nolan, D., McKinnon, E., Hammond, E. and Mallal, S. (2003) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipodystrophy: Trends in subcutaneous fat wasting and association with mitochondrial DNA depletion. In: 7th International Workshop on HIV Observational Databases, 28-30 March 2003, Fiuggi, Italy.

Hammond, E., Nolan, D., James, I., McKinnon, E., White, A. and Mallal, S. (2003) Evidence of toxicity in Adipose tissue of HIV-infected patients correlates with NRTI-associated mtDNA depletion. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Mallal, S., Moore, C., Carvalho, F., Patterson, A., Liu, C., Goodridge, D., Sayer, D., James, I. and John, M. (2003) HIV adaptation to HLA-restricted immune responses - implications for vaccine design and evaluation. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Cherry, C., Nolan, D., James, I., Mallal, S., McKinnon, E., French, M., Hammond, E., Gahan, M., McArthur, J. and Wesselingh, S. (2003) Longitudinal associations between antiretroviral treatments and quantification of tissue mitochondrial DNA from ambulatory subjects with HIV infection. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

James, I., Nolan, D., Hammond, E., McKinnon, E. and Mallal, S. (2003) Longitudinal effects on subcutaneous fatmass of initiating or switching stavudine and zidovudine-based antiretroviral therapy. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Christiansen, F.T., Gaudieri, S., De Santis, D., Moore, C.B., Witt, C.S., James, I.R. and Mallal, S. (2003) NK receptor genes are predictors of HIV progression. In: 29th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 28 October - 1 November 2003, Miami Beach, Florida.

McKinnon, E.J., James, I.R. and Mallal, S. (2003) Response to HAART: Host genetic associations. In: Annual North American Observational Database Meeting, 13 November 2003, Washington DC, U.S.A.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2003) Subcutaneous fat tissue mitochondrial DNA depletion and adipose toxicity are strongly associated with nucleoside reverse transcriptase inhibitor (NRTI) therapy in HIV-infected patients. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

McKinnon, E., Fusco, J., John, M., Fusco, G., James, I. and Mallal, S. (2003) Virological response to first HAART - a CHORUS/WAHIV collaborative study. In: 7th International Workshop on HIV Observational Databases, 28-30 March 2003, Fiuggi, Italy.

Christiansen, F.T., Gaudieri, S., Moore, C.B., Martin, A., Nolan, D., James, I.R., McKinnon, E., DeSantis, D., Witt, C.S. and Mallal, S. (2003) The immune response to HIV: The interplay between virus and host genetic factors. In: British Society for Immunology Annual Congress, 2 - 5 December 2003, Harrogate, England.

McKinnon, E., Fusco, J., Fusco, G., John, M., James, I. and Mallal, S. (2002) Virologic response to HAART in the CHORUS cohort. In: GSK Observational HIV Cohorts Meeting, 6 - 7 November 2002, Boston, U.S.A.

Moore, C., John, M., James, I. and Mallal, S. (2002) The influence of host HLA on antiretroviral drug resistance mutation in HIV-1. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

Mallal, S., Witt, C., Martin, A.M., Masel, G., Moore, C., Sayer, D., Castley, A., Mamotte, C., Nolan, D., James, I. and Christiansen, F.T. (2002) The presence of HLA-B*5701, -DRB1*0701 and -DQ3 is highly predictive of hypersensitivity to the HIV reverse transcriptase inihibitor abacavir. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A.

John, M., James, I., McKinnon, E., Nolan, D., Herrmann, S., Cain, A., Martinez, O.P., White, A. and Mallal, S. (2002) A randomised, controlled, Open-label study of revision of antiretroviral regimens containing stavudine (d4T) and/or a Protease Inhibitor (PI) to Zidovudine (ZDV)/Lamivudine (3TC)/Abacavir (ABC) to prevent or reverse lipoatrophy: 48-week data. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada.

Mallal, S., Mallon, D.J.F., Cameron, P.U., James, I.R. and French, M.A.H. (1995) The influence of past Toxoplasma gondii, syphilis, Hepatitis B and C and Cytomegalovirus infections on survival of HIV-1 infected participants of the Western Australian HIV Cohort Study. In: 2nd National Conference on Human Retroviruses and Related Infections, 27 January - 2 Feb 1995, Washington DC.

Mallon, D.J.F., Mallal, S., James, I.R. and French, M.A.H. (1994) Infection with some co-pathogens influences HIV-related mortality. In: Australasian Society for HIV Medicine (ASHM) 6th Annual Conference , 3 - 6 November 1994, Manly Pacific Park Royal, Sydney.

This list was generated on Wed Jul 23 10:52:39 2014 IST.