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Number of items at this level: 333.

2013

Qiu, W., Pham, K., James, I., Nolan, D., Castley, A., Christiansen, F.T., Czarniak, P., Luo, Y., Wu, J., Garlepp, M., Wilton, S., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2013) The influence of non-HLA gene polymorphisms and interactions on disease risk in a Western Australian multiple sclerosis cohort. Journal of Neuroimmunology, 261 (1-2). pp. 92-97.

Rojana-udomsart, A., Mitrpant, C., James, I., Witt, C., Needham, M., Day, T., Kiers, L., Corbett, A., Martinez, P., Wilton, S.D. and Mastaglia, F.L. (2013) Analysis of HLA-DRB3 alleles and supertypical genotypes in the MHC Class II region in sporadic inclusion body myositis. Journal of Neuroimmunology, 254 (1-2). pp. 174-177.

2012

Achhra, A.C., Amin, J., Hoy, J., Tanuma, J., Sirisanthana, T., Nolan, D., Merati, T. and Giles, M. (2012) Differences in lipid measurements by antiretroviral regimen exposure in cohorts from Asia and Australia. AIDS Research and Treatment, 2012 . pp. 1-9.

Blais, M.-E., Zhang, Y., Rostron, T., Griffin, H., Taylor, S., Xu, K., Yan, H., Wu, H., James, I., John, M., Dong, T. and Rowland-Jones, S. L. (2012) High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C - Restricted CTL selective pressure associated with an AIDS-protective polymorphism. The Journal of Immunology, 188 (9). pp. 4663-4670.

Bourke, J., Pavlos, R., Hollingsworth, P., McLean-Tooke, A., Horimoto, N., O'Brien, V., Edward, E. and Phillips, E. (2012) Penicillin de-labelling in tertiary clinics: Safe and efficacious but incomplete effectiveness. In: ASCIA 23rd Annual Scientific Meeting, 5 - 8 September 2012, Wellington, New Zealand.

Carlson, J.M., Brumme, C.J., Martin, E., Listgarten, J., Brockman, M.A., Le, A.Q., Chui, C.K.S., Cotton, L.A., Knapp, D.J.H.F., Riddler, S.A., Haubrich, R., Nelson, G., Pfeifer, N., DeZiel, C.E., Heckerman, D., Apps, R., Carrington, M., Mallal, S., Harrigan, P.R., John, M. and Brumme, Z.L. (2012) Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1. Journal of Virology, 86 (24). pp. 13202-13216.

Keane, N.M., Roberts, S.G., Almeida, C.M., Krishnan, T., Chopra, A., Demaine, E., Laird, R., Tschochner, M., Carlson, J.M., Mallal, S., Heckerman, D., James, I. and John, M. (2012) High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection. Immunology and Cell Biology, 90 (2). pp. 224-234.

Lee, M.H., Stocker, S.L., Anderson, J., Phillips, E.J., Nolan, D., Williams, K.M., Graham, G.G., Sullivan, J.R. and Day, R.O. (2012) Initiating allopurinol therapy: do we need to know the patient's human leucocyte antigen status? Internal Medicine Journal, 42 (4). pp. 411-416.

Loh, N.K., Lucas, M., Fernandez, S. and Prentice, D. (2012) Successful treatment of macrophage activation syndrome complicating adult Still disease with anakinra. Internal Medicine Journal, 42 (12). pp. 1358-1362.

Rajasuriar, R., Booth, D.R., Gouillou, M., Spelman, T., James, I., Solomon, A., Chua, K., Stewart, G., Deeks, S., Bangsberg, D.R., Muzoora, C., Cameron, P.U., Hunt, P., Martin, J. and Lewin, S.R. (2012) The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART. Genes and Immunity, 13 (1). pp. 83-93.

Rojana-udomsart, A., Bundell, C., James, I., Castley, A., Martinez, P., Christiansen, F., Hollingsworth, P. and Mastaglia, F. (2012) Frequency of autoantibodies and correlation with HLA-DRB1 genotype in sporadic inclusion body myositis (s-IBM): A population control study. Journal of Neuroimmunology, 249 (1-2). pp. 66-70.

Rojana-udomsart, A., Castley, A, James, I., Needham, M., Scott, A., Day, T., Kiers, L., Corbett, A., Sue, C., Martinez, P., Christiansen, F. and Mastaglia, F.L. (2012) G.P.63 High-resolution analysis of HLA-DRB1 alleles and diplotypes in an Australian inclusion body myositis cohort. Neuromuscular Disorders, 22 (9-10). pp. 853-854.

Rojana-udomsart, A., James, I., Castley, A., Needham, M., Scott, A., Day, T., Kiers, L., Corbett, A., Sue, C., Witt, C., Martinez, P., Christiansen, F. and Mastaglia, F. (2012) High-resolution HLA-DRB1 genotyping in an Australian inclusion body myositis (s-IBM) cohort: An analysis of disease-associated alleles and diplotypes. Journal of Neuroimmunology, 250 (1-2). pp. 77-82.

2011

Almeida, C.M., Bronke, C., Roberts, S.G., McKinnon, E., Keane, N.M., Chopra, A., Kadie, C., Carlson, J., Haas, D. W., Riddler, S. A., Haubrich, R., Heckerman, D., Mallal, S. and John, M. (2011) Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes. The Journal of Immunology, 187 (5). pp. 2502-2513.

Dong, T., Zhang, Y., Xu, K. Y., Yan, H., James, I., Peng, Y., Blais, M.-E., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W. Y., Rostron, T., Li, N., Mao, Y., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. L. (2011) Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Blood, 118 (1). pp. 98-106.

Fitzmaurice, K., Petrovic, D., Ramamurthy, N., Simmons, R., Merani, S., Gaudieri, S., Sims, S., Dempsey, E., Freitas, E., Lea, S., McKiernan, S., Norris, S., Long, A., Kelleher, D. and Klenerman, P. (2011) Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection. Gut, 60 (11). pp. 1563-1571.

Lucas, M., Nicol, P., McKinnon, E., Whidborne, R., Lucas, A.D., Thambiran, A., Burgner, D., Waring, J. and French, M. (2011) The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children. Thorax, 66 (3). p. 265.

Merani, S., Petrovic, D., James, I., Chopra, A., Cooper, D., Freitas, E., Rauch, A., di Iulio, J., John, M., Lucas, M., Fitzmaurice, K., McKiernan, S., Norris, S., Kelleher, D., Klenerman, P. and Gaudieri, S. (2011) Effect of immune pressure on hepatitis C virus evolution: Insights from a single-source outbreak. Hepatology, 53 (2). pp. 396-405.

Morahan, G., Mehta, M., James, I., Chen, W.-M., Akolkar, B., Erlich, H. A., Hilner, J. E., Julier, C., Nerup, J., Nierras, C., Pociot, F., Todd, J. A. and Rich, S. S. (2011) Tests for genetic interactions in Type 1 Diabetes: Linkage and stratification analyses of 4,422 affected Sib-Pairs. Diabetes, 60 (3). pp. 1030-1040.

Olcaydu, D., Rumi, E., Harutyunyan, A., Passamonti, F., Pietra, D., Pascutto, C., Berg, T., Jager, R., Hammond, E.L., Cazzola, M. and Kralovics, R. (2011) The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms. Haematologica, 96 (3). pp. 367-374.

Pfafferott, K., Gaudieri, S., Ulsenheimer, A., James, I., Heeg, M., Nolan, D., John, M., Rauch, A., Mallal, S., Lucas, A.D., Klenerman, P., Diepolder, H.M. and Lucas, M. (2011) Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity. PLoS ONE, 6 (2). e16797.

Pirmohamed, M., Friedmann, P.S., Molokhia, M., Loke, Y.K., Smith, C., Phillips, E., La Grenade, L., Carleton, B., Papaluca-Amati, M., Demoly, P. and Shear, N.H. (2011) Phenotype Standardization for Immune-Mediated Drug-Induced Skin Injury. Clinical Pharmacology & Therapeutics, 89 (6). pp. 896-901.

Qiu, W., James, I., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2011) HLA-DR allele polymorphism and multiple sclerosis in Chinese populations: a meta-analysis. Multiple Sclerosis, 17 (4). pp. 382-388.

Qiu, W., Raven, S., James, I., Luo, Y., Wu, J., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2011) Spinal cord involvement in multiple sclerosis: A correlative MRI and high-resolution HLA-DRB1 genotyping study. Journal of the Neurological Sciences, 300 (1-2). pp. 114-119.

Zhang, Y., Peng, Y., Yan, H., Xu, K., Saito, M., Wu, H., Chen, X., Ranasinghe, S., Kuse, N., Powell, T., Zhao, Y., Li, W., Zhang, X., Feng, X., Li, N., Leligdowicz, A., Xu, X., John, M., Takiguchi, M., McMichael, A., Rowland-Jones, S. and Dong, T. (2011) Multilayered defense in HLA-B51-associated HIV viral control. The Journal of Immunology, 187 (2). pp. 684-691.

2010

Almeida, C.M., Roberts, S.G., Laird, R., McKinnon, E., Ahmad, I., Keane, N.M., Chopra, A., Kadie, C., Heckerman, D., Mallal, S. and John, M. (2010) Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses. Vaccine, 28 (37). pp. 6052-6057.

Breen, J., Li, D., Dunn, D.S., Bekes, F., Kong, X., Zhang, J., Jia, J., Wicker, T., Mago, R., Ma, W., Bellgard, M. and Appels, R. (2010) Wheat beta-expansin (EXPB11) genes: Identification of the expressed gene on chromosome 3BS carrying a pollen allergen domain. BMC Plant Biology, 10 (1). p. 99.

Falster, K., Wand, H., Donovan, B., Anderson, J., Nolan, D., Watson, K., Watson, J. and Law, M.G (2010) Hospitalizations in a cohort of HIV patients in Australia, 1999–2007. AIDS, 24 (9). pp. 1329-1339.

Friis-Møller, N., Thiébaut, R., Reiss, P., Weber, R., Monforte, A.D., De Wit, S., El-Sadr, W., Fontas, E., Worm, S., Kirk, O., Phillips, A., Sabin, C.A., Lundgren, J.D., Law, M.G., Mallal, S. and Nolan, D. (2010) Predicting the risk of cardiovascular disease in HIV-infected patients: The Data collection on Adverse Effects of Anti-HIV Drugs Study. European Journal of Cardiovascular Prevention & Rehabilitation, 17 (5). pp. 491-501.

Hammond, E.L., McKinnon, E. and Nolan, D. (2010) Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences. Clinical Infectious Diseases, 51 (5). pp. 591-599.

Iwabu, Y., Kinomoto, M., Tatsumi, M., Fujita, H., Shimura, M., Tanaka, Y., Ishizaka, Y., Nolan, D., Mallal, S., Sata, T. and Tokunaga, K. (2010) Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes. Journal of Biological Chemistry, 285 (46). pp. 35350-35358.

James, I. (2010) Correlation estimation with bivariate censored data via alternating regressions. In: ASC 2010 Australian Statistical Conference Statistics in the West: Understanding our World., 6 - 10 December, Fremantle, Western Australia.

John, M., Heckerman, D., James, I., Park, L.P., Carlson, J.M., Chopra, A., Gaudieri, S., Nolan, D., Haas, D.W., Riddler, S.A., Haubrich, R. and Mallal, S. (2010) Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. The Journal of Immunology, 184 (8). pp. 4368-4377.

Keane, N.M., Pfafferott, K., Cooper, D., Roberts, S.G., Chopra, A., Demaine, E., Krishnan, T., Mallal, S. and John, M. (2010) HIV-1 adaptation to early HLA restricted immune responses in acute heterosexual transmission. In: 22nd Annual Conference of the Australasian Society for HIV Medicine, 20 - 22 October 2010, Sydney, Australia

Lucas, M., Nicol, P., McKinnon, E., Whidborne, R., Lucas, A.D., Thambiran, A., Burgner, D., Waring, J. and French, M. (2010) A prospective large-scale study of methods for the detection of latent Mycobacterium tuberculosis infection in refugee children. Thorax, 65 (5). pp. 442-448.

Phillips, E.J. and Mallal, S. (2010) Pharmacogenetics of drug hypersensitivity. Pharmacogenomics, 11 (7). pp. 973-987.

Qiu, W., Wu, J-S, Castley, A., James, I., Joseph, J., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia. Journal of Clinical Neuroscience, 17 (8). pp. 1009-1013.

Qiu, W., Bundell, C., Wu, J.-S., Castley, A., James, I., Hollingsworth, P., Christiansen, F., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Low level of systemic autoimmunity in Western Australian multiple sclerosis patients. Multiple Sclerosis, 16 (3). pp. 351-354.

Rohrbach, J., Robinson, N., Harcourt, G., Hammond, E.L., Gaudieri, S., Gorgievski, M., Telenti, A., Keiser, O., Gunthard, H. F., Hirschel, B., Hoffmann, M., Bernasconi, E., Battegay, M., Furrer, H., Klenerman, P., Rauch, A. and Swiss HIV Cohort Study, . (2010) Cellular immune responses to HCV core increase and HCV RNA levels decrease during successful antiretroviral therapy. Gut, 59 (9). pp. 1252-1258.

Smyth, R.P., Schlub, T.E., Grimm, A., Venturi, V., Chopra, A., Mallal, S., Davenport, M.P. and Mak, J. (2010) Reducing chimera formation during PCR amplification to ensure accurate genotyping. Gene, 469 (1-2). pp. 45-51.

Tschochner, M., Rohrbach, J., Cooper, D., Merani, S., Chopra, A., Witteck, A., Battegay, M., Furrer, H., Günthard, H., Mallal, S., Rauch, A. and Gaudieri, S. (2010) Characterisation of hepatitis C virus evolution in HIV/HCV coinfected individuals using deep sequencing technology: Relevance for new antiviral drugs and disease outcome. In: 22nd Annual Conference of the Australasian Society for HIV Medicine, 20 - 22 October 2010, Sydney, Australia

Worm, S.W., Friis-Møller, N., Bruyand, M., Monforte, A.D., Rickenbach, M., Reiss, P., El-Sadr, W., Phillips, A., Lundgren, J., Sabin, C. and Mallal, S. (2010) High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndrome. AIDS, 24 (3). pp. 427-435.

Wu, J-S, James, I., Qiu, W., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) HLA-DRB1 allele heterogeneity influences multiple sclerosis severity as well as risk in Western Australia. Journal of Neuroimmunology, 219 (1-2). pp. 109-113.

Wu, J-S, Qiu, W., Castley, A., James, I., Joseph, J., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort. Journal of the Neurological Sciences, 288 (1-2). pp. 63-67.

Wu, J-S, Qiu, W., Castley, A., James, I., Mastaglia, F.L., Christiansen, F.T, Carroll, W.M, Joseph, J. and Kermode, A.G. (2010) Modifying effects of HLA-DRB1 allele interactions on age at onset of multiple sclerosis in Western Australia. Multiple Sclerosis, 16 (1). pp. 15-20.

Wu, J.S., James, I., Wei, Q., Castley, A., Christiansen, F.T., Carroll, W.M., Mastaglia, F.L. and Kermode, A.G. (2010) Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution genotyping study. Multiple Sclerosis, 16 (5). pp. 526-532.

2009

Almeida, C.M., Roberts, S.G., Laird, R., McKinnon, E., Ahmad, I., Pfafferott, K., Turley, J., Keane, N.M., Lucas, A.D., Rushton, B.C., Chopra, A., Mallal, S. and John, M. (2009) Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses. Journal of Immunological Methods, 344 (1). pp. 1-5.

Avila-Rios, S., Ormsby, C.E., Carlson, J.M., Valenzuela-Ponce, H., Blanco-Heredia, J., Garrido-Rodriguez, D., Garcia-Morales, C., Heckerman, D., Brumme, Z.L., Mallal, S., John, M., Espinosa, E. and Reyes-Teran, G. (2009) Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study. Retrovirology, 6 . p. 72.

Brumme, Z.L., John, M., Carlson, J.M., Brumme, C.J., Chan, D., Brockman, M.A., Swenson, L.C., Tao, I., Szeto, S., Rosato, P., Sela, J., Kadie, C.M., Frahm, N., Brander, C., Haas, D.W., Riddler, S.A., Haubrich, R., Walker, B.D., Harrigan, P.R., Heckerman, D., Mallal, S. and Nixon, D.F. (2009) HLA-Associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. PLoS ONE, 4 (8). e6687.

Brumme, Z.L., Rosato, P., Sela, J., Brumme, C.J., Brockman, M.A., John, M., Carlson, J.M., Baker, B.M., Streeck, H., Swenson, L., Chan, D., Markowitz, M., Jessen, H., Kelleher, A., Rychert, J., Rosenberg, E., Allen, T., Altfeld, M., Berger, C.T., Frahm, N., Brander, C., Harrigan, P.R., Mallal, S., Heckerman, D. and Walker, B.D. (2009) Sites and kinetics of HLA-associated immune escape in HIV-1 integrase. In: 5th IAS Conference on HIV Pathogenesis and Treatment and Prevention, 19 - 22 July 2009, Cape Town, South Africa.

Brumme, Z.L., Rosato, P., Sela, J., Mallal, S. and Heckerman, D. (2009) HLA class-I driven evolution in HIV-1 integrase in the first year of infection. In: Keystone Meeting. HIV Vaccine & Pathogenesis, 22 - 27 March 2009, Colorado, USA.

Carey, D., Baker, D., Petoumenos, K., Chuah, J., Rogers, G.D., Watson, J., Cooper, D.A., Emery, S., Carr, A. and Nolan, D. (2009) Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-up. HIV Medicine, 10 (3). pp. 163-172.

D'Orsogna, L.J., Wright, M.P., Krueger, R.G., McKinnon, E.J., Buffery, S.I., Witt, C.S., Staples, N., Loh, R., Cannell, P.K., Christiansen, F.T. and French, M.A. (2009) Allogeneic hematopoietic stem cell transplantation recipients have defects of both switched and IgM memory B cells. Biology of Blood and Marrow Transplantation, 15 (7). pp. 795-803.

Desmond, C.P., Gaudieri, S., James, I., Pfafferott, K., Chopra, A., Lau, G.K., Locarnini, S.A., Revill, P.A., Day, C.F., Chivers, S., Gordon, A., Bowden, S., Ayres, A., Desmond, P.V., Thompson, A.J., Roberts, S.K., Mallal, S. and Lewin, S.R. (2009) Identification of novel hepatitis B virus (HBV) T-cell epitopes and escape mutations in Asian individuals with chronic HBV infection using a population based approach. In: 60th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2009, 30 October - 3 November 2009, Boston, U.S.A.

Dong, T., Zhang, Y., Xu, K., Yan, H., James, I., Peng, Y., Blais, M., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W., Zhao, C., Li, N., Mao, Y., Rostron, T., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. (2009) P20-19 LB. Extensive HLA-driven viral diversity following a single-source HIV-1 outbreak in rural China. Retrovirology, 6 (Suppl 3). P423.

Dong, T., Zhang, Y., Xu, K., Yan, H., James, I., Peng, Y., Blais, M., Gaudieri, S., Chen, X., Lun, W., Wu, H., Qu, W., Zhoo, C., Li, N., Mao, Y., Rostron, T., Mallal, S., Xu, X., McMichael, A., John, M. and Rowland-Jones, S. (2009) Extensive HLA-driven viral diversity following a single-source HIV-1 outbreak in rural China. In: AIDS Vaccine 2009, 19 - 22 October 2009, Paris, France.

Egger, S., Petoumenos, K., Kamarulzaman, A., Hoy, J., Sungkanuparph, S., Chuah, J., Falster, K., Zhou, J., Law, M.G., Mallal, S. and Nolan, D. (2009) Long-term patterns in CD4 response are determined by an interaction between baseline CD4 cell count, viral load, and time: The Asia Pacific HIV Observational Database (APHOD). JAIDS Journal of Acquired Immune Deficiency Syndromes, 50 (5). pp. 513-520.

Falster, K., Choi, J.Y., Donovan, B., Duncombe, C., Mulhall, B., Sowden, D., Zhou, J., Law, M.G., Mallal, S. and Nolan, D. (2009) AIDS-related and non-AIDS-related mortality in the Asia-Pacific region in the era of combination antiretroviral treatment. AIDS, 23 (17). pp. 2323-2336.

Fellay, J., Ge, D., Shianna, K.V., Colombo, S., Ledergerber, B., Cirulli, E.T., Urban, T.J., Zhang, K., Gumbs, C.E., Smith, J. P., Castagna, A., Cozzi-Lepri, A., De Luca, A., Easterbrook, P., Günthard, H.F., Mallal, S., Mussini, C., Dalmau, J., Martinez-Picado, J., Miro, J.M., Obel, N., Wolinsky, S.M., Martinson, J.J., Detels, R., Margolick, J.B., Jacobson, L.P., Descombes, P., Antonarakis, S.E., Beckmann, J.S., O'Brien, S.J., Letvin, N.L., McMichael, A.J., Haynes, B.F., Carrington, M., Feng, S., Telenti, A., Goldstein, D.B. and McCarthy, M.I. (2009) Common genetic variation and the control of HIV-1 in humans. PLoS Genetics, 5 (12). e1000791.

Gaudieri, S., Rauch, A., Pfafferott, K., Barnes, E., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G.P., Mollison, L., Baker, R., Furrer, H., Günthard, H.F., Freitas, E., Humphreys, I., Klenerman, P., Mallal, S., James, I., Roberts, S., Nolan, D. and Lucas, M. (2009) Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy. Hepatology, 49 (4). pp. 1069-1082.

James, I., McKinnon, E., Gaudieri, S. and Morahan, G. (2009) Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 101-107.

Kawashima, Y., Pfafferott, K., Frater, J., Matthews, P., Payne, R., Addo, M., Gatanaga, H., Fujiwara, M., Hachiya, A., Koizumi, H., Kuse, N., Oka, S., Duda, A., Prendergast, A., Crawford, H., Leslie, A., Brumme, Z., Brumme, C., Allen, T., Brander, C., Kaslow, R., Tang, J., Hunter, E., Allen, S., Mulenga, J., Branch, S., Roach, T., John, M., Mallal, S., Ogwu, A., Shapiro, R., Prado, J.G., Fidler, S., Weber, J., Pybus, O.G., Klenerman, P., Ndung’u, T., Phillips, R., Heckerman, D., Harrigan, P.R., Walker, Bruce D., Takiguchi, M. and Goulder, P. (2009) Adaptation of HIV-1 to human leukocyte antigen class I. Nature, 458 (7238). pp. 641-645.

Keane, N., Roberts, S., Laird, R., Chopra, A., Krishnan, T., Almeida, C., Bronke, C., Mallal, S., James, I. and John, M. (2009) P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy. In: AIDS Vaccine 2009, 19 - 22 October 2009, Paris, France.

Keane, N.M., Roberts, S.G., Laird, R., Chopra, A., Krishnan, T., Almeida, C.M., Bronke, C., Mallal, S., James, I. and John, M. (2009) P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy. Retrovirology, 6 (Suppl 3, 22 October 2009). P128.

Mallal, S. (2009) Pharmacogenetic testing in HIV therapy. In: Genes for Health Conference 2009, 2 - 6 May 2009, Fremantle, Western Australia.

Mastaglia, F.L., Needham, M., Scott, A., James, I., Zilko, P., Day, T., Kiers, L., Corbett, A., Witt, C.S., Allcock, R., Laing, N., Garlepp, M. and Christiansen, F.T. (2009) Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype. Neuromuscular Disorders, 19 (11). pp. 763-765.

McKinnon, E., Morahan, G., Nolan, D. and James, I. (2009) Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 92-100.

Miura, T., Brumme, C. J., Brockman, M. A., Brumme, Z. L., Pereyra, F., Block, B. L., Trocha, A., John, M., Mallal, S., Harrigan, P. R. and Walker, B. D. (2009) HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers. Journal of Virology, 83 (7). pp. 3407-3412.

Mocroft, A., Sterne, J.A., Egger, M., May, M., Grabar, S., Furrer, H., Sabin, C., Fatkenheuer, G., Justice, A., Reiss, P., D'Arminio Monforte, A., Gill, J., Hogg, R., Bonnet, F., Kitahata, M., Staszewski, S., Casabona, J., Harris, R., Saaq, M. and Phillips, E. (2009) Variable impact on mortality of AIDS‐Defining events diagnosed during combination antiretroviral therapy: Not All AIDS‐defining conditions are created equal. Clinical Infectious Diseases, 48 (8). pp. 1138-1151.

Morahan, G., McKinnon, E., Berry, J., Browning, B., Julier, C., Pociot, F. and James, I. (2009) Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium. Genes and Immunity, 10 . S64-S68.

Morahan, G., Mehta, M., McKinnon, E. and James, I. (2009) Effect of linkage status of affected sib-pairs on the search for novel type 1 diabetes susceptibility genes in the HLA complex. Diabetes, Obesity and Metabolism, 11 (Supp. 1). pp. 67-73.

Netto, J., Keane, N., Mullaney, I., Nolan, D., Mallal, S. and Trengove, R. (2009) The alternate metabolism of abacavir and its role in immune-mediated hypersensitivity reactions in HIV infected individuals. In: 57th ASMS Conference on Mass Spectrometry and Allied Topics, 31 May - 4 June 2009, Philadelphia, USA.

Nolan, D. (2009) HLA-B*5701 screening prior to abacavir prescription: Clinical and laboratory aspects. Critical Reviews in Clinical Laboratory Sciences, 46 (3). pp. 153-165.

Phillips, E.J. and Mallal, S. (2009) Successful translation of pharmacogenetics into the clinic: The abacavir example. Molecular Diagnosis and Therapy, 13 (1). pp. 1-9.

Phillips, E.J. (2009) Pharmacogenetic of drug hypersensitivity: Personalising medicine and predicting the unpredictable. In: WAMSG 5th Annual Medication Safety Symposium: ADRs ain'y just ADRs: Action on Adverse Drug Reactions for Medication Safety, 14 July 2009, University Club, University of Western Australia, Crawley.

Price, P. and James, I. (2009) IL1A alleles associate with a virological response to antiretroviral therapy in HIV patients beginning therapy with advanced disease. AIDS, 23 (9). pp. 1173-1176.

Rauch, A., James, I., Pfafferott, K., Nolan, D., Klenerman, P., Cheng, W., Mollison, L., McCaughan, G., Shackel, N., Jeffrey, G.P., Baker, R., Freitas, E., Humphreys, I., Furrer, H., Günthard, H.F., Hirschel, B., Mallal, S., John, M., Lucas, M., Barnes, E. and Gaudieri, S. (2009) Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure. Hepatology, 50 (4). pp. 1017-1029.

Rauch, A., Gaudieri, S., Thio, C. and Bochud, P-Y (2009) Host genetic determinants of spontaneous hepatitis C clearance. Pharmacogenomics, 10 (11). pp. 1819-1837.

Tschochner, M., Chopra, A., Maiden, T.M., Ahmad, I.F., James, I., Furrer, H., Günthard, H., Mallal, S., Rauch, A. and John, M. (2009) Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance. Antiviral Therapy, 14 (7). pp. 953-964.

Wald, A., Margaret, A.S., John, M., Mallal, S., Corey, L. and Koelle, D.M. (2009) HLA A*01 and B*08 are associated with increased genital shredding of HSV-2. In: 18th Meeting of the International Society for STD Research (ISSTDR) in conjunction with the British Association for Sexual Health & HIV (BASHH), 28 June - 1 July 2009, London, UK.

2008

Almeida, C.M., Martin, A.M., Nolan, D., Lucas, A., Cameron, P.U., James, I., Phillips, E. and Mallal, S. (2008) Cytokine profiling in abacavir hypersensitivity patients. Antiviral Therapy, 13 (2). pp. 281-288.

Brumme, C.J., Brumme, Z.L., Carlson, J., Markowitz, M., Jensen, H., Kelleher, A., John, M., Mallal, S., Allen, T., Heckerman, D. and Walker, B.D. (2008) Reversion of HLA-Associated Polymorphisms in GAG, POL and NEF during the first year of HIV infection: Sites, Rates and pVL correlations. In: AIDS Vaccine 2008, 13 - 16 October, Cape Town, South Africa.

Brumme, Z. L., Brumme, C. J., Carlson, J., Streeck, H., John, M., Eichbaum, Q., Block, B. L., Baker, B., Kadie, C., Markowitz, M., Jessen, H., Kelleher, A. D., Rosenberg, E., Kaldor, J., Yuki, Y., Carrington, M., Allen, T. M., Mallal, S., Altfeld, M., Heckerman, D. and Walker, B. D. (2008) Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. Journal of Virology, 82 (18). pp. 9216-9227.

Brumme, Z.L., Brumme, C.J., Carlson, J.M. and Mallal, S. (2008) HLA class I-associated immune selection pressure drives a major portion of HIV-1 evolution in early infection. In: Keystone Symposia - HIV Vaccines: Progress and Prospects, 27 March - 1 April 2008, Banff, Canada.

Brumme, Z.L., John, M., Brumme, C.J., Carlson, J.M., Haubrich, R., Riddler, S., Swenson, L., Tao, I., Szeto, S., Chan, D., Kadie, C., Frahm, N., Brander, C., Walker, B., Heckerman, D., Harrigan, P.R. and Mallal, S. (2008) Relationship between HLA class I-driven evolution in Gag, Pol and Nef and clinical markers of HIV disease: A multi-center collaborative study. In: AIDS Vaccine 2008, 13 - 16 October, Cape Town, South Africa.

Bugawan, T., Isoda, W., Mallal, S., Thorborn, D. and Erlich, H. (2008) HLA-B*5701 Taqman assay for abacavir sensitivity: Application to PREDICT-1 trial. In: 34th Annual Meeting of the American Society for Histocompatibility and Immunogenetics (ASHI) 2008, 27 - 31 October 2008, Toronto, Canada.

Bugawan, T., Isoda, W., Mano, C., Blair, A., Mallal, S., Thorborn, D. and Erlich, H. (2008) HLA-B*5701 Taqman assay for abacavir sensitivity: Application to PREDICT-1 trial. In: 15th International Histocompatibility and Immunogenetics Workshop (IHW), 13 - 26 September 2008, Rio de Janeiro, Brazil.

Chessman, D., Kostenko, L., Lethborg, T., Purcell, A.W., Williamson, N.A., Chen, Z., Kjer-Nielsen, L., Mifsud, N.A., Tait, B.D., Holdsworth, R., Almeida, C.M., Nolan, D., Macdonald, W.A., Archbold, J.K., Kellerher, A.D., Marriott, D., Mallal, S., Bharadwaj, M., Rossjohn, J. and McCluskey, J. (2008) Human leukocyte Antigen Class I-restricted activation of CD8+ T Cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity, 28 (6). pp. 822-832.

Desmond, C.P., Gaudieri, S., Pfafferott, K., Chopra, A., Mallal, S. and Lewin, S.R. (2008) The impact of HLA on hepatitis B virus (HBV) sequence polymorphism in Asian individuals with chronic HBV infection. In: The European Association for Study of the Liver (EASL)Monothematic Conference: Immune Mediated Liver Injury, 4 - 6 December 2008, Hamburg, Germany.

Duracinsky, M., Acquadro, C., Herrmann, S., Berzins, B., Le Coeur, S., Kohli, R., Ban, B., Ferro do Lago, R. and Chassany, O. (2008) International development of a new health-related quality of life questionnaire specific to HIV/AIDS – item banking. In: XVII International AIDS Conference, 3 - 8 August, Mexico City, Mexico.

Duracinsky, M., Herrmann, S., Acquadro, C., Berzins, B., Le Coeur, S., Hyland, N., Fournier, I., McKinnon, E., Nolan, D., Mallal, S. and Chassany, O. (2008) Development of a new health-related quality of life questionnaire specific to HIV/AIDS: an international and cross cultural initiative. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

EuroCHAVI Genome Consortium, . and Mallal, S. (2008) Host genome analysis in HIV disease, progress and validation. In: 12th International Workshop on HIV Observational Databases, 27 - 30 March 2008, Malaga, Spain.

Gaudieri, S., Rauch, A., Mallal, S., Roberts, S., Nolan, D. and Lucas, M. (2008) Overlapping selection of hepatitis C virus drug-resistant mutations and immune-driven adaptations. In: Australian Centre for HIV and Hepatitis Virology Research (ACH2) 4th Annual Workshop, 4 - 6 June 2008, Novotel Barossa Valley Resort, South Australia.

Gaudieri, S., Rauch, A., Pfafferott, K., Mallal, S. and Roberts, S. (2008) Co-localisation of HCV drug resistant mutations and immune-driven adaptations for Genotype 1 and 3: Relevance to therapy outcome. In: Australasian Viral Hepatitis Meeting 2008, 20 - 22 October 2008, Brisbane, Australia.

Guallar, J.P., Gallego-Escuredo, J.M., Domingo, J.C., Alegre, M., Fontdevila, J., Martínez, E., Hammond, E.L., Domingo, P., Giralt, M. and Villarroya, F. (2008) Differential gene expression indicates that ‘buffalo hump’ is a distinct adipose tissue disturbance in HIV-1-associated lipodystrophy. AIDS, 22 (5). pp. 575-584.

Hammond, E.L., Martin, A., Nolan, D., Metcalf, C. and Mallal, S. (2008) Eruptive haemangioma associated with HIV therapy and mitochondrial pathology. Pathology, 40 (4). pp. 425-429.

Hammond, E.L., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. AIDS, 22 (18). pp. 2540-2543.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. In: 10th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 6 - 8 November 2008, London, England.

Hammond, E., McKinnon, E., Mallal, S. and Nolan, D. (2008) Pathogenesis of lipoatrophy: Analysis of tissue and plasma. In: 10th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 6 - 8 November 2008, London, England.

Hammond, E., McKinnon, E., Pace, C., Mallal, S. and Nolan, D. (2008) Influence of NRTI choice and efavirenz versus lopinavir treatment options on lipoatrophy-associated adipose tissue toxicity: A longitudinal study. In: 15th Conference on Retroviruses and Opportunistic Infections (CROI), 3 - 6 February 2008, Boston, U.S.A.

Heckerman, D., Brumme, C.J., John, M., Carlson, J.M., Swenson, L., Tao, I., Szeto, S., Kadie, C., Frahm, N., Brander, C., Walker, B., Brumme, Z.L., Harrigan, P.R. and Mallal, S. (2008) Differential impact of HLA class I-driven evolution in Gag, Pol and Nef on HIV disease markers: A multicenter, international collaborative study. In: Keystone Symposia - HIV Vaccines: Progress and Prospects, 27 March - 1 April 2008, Banff, Canada.

Heckerman, D., Brumme, C.J., John, M. and Mallal, S. (2008) Relationship between HLA class I-driven evolution in Gag, Pol and Nef and clinical markers of HIV disease: A multi-center collaborative study. In: 15th International HIV Dynamics & Evolution Meeting, 27 - 30 April 2008, Santa Fe, New Mexico.

Herrmann, S., McKinnon, E., John, M., Nolan, D., Martinez, O.P., Phillips, E. and Mallal, S. (2008) Side effects, dosing schedules, pill burden and perceived stress: Interaction and influence on medication adherence. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Keane, N.M., Laird, R., Chopra, A., Maiden, T., Almeida, C., Mallal, S. and John, M. (2008) An HLA-C*0702 restricted T-Cell response directed against an immune escaped HIV NEF KY11 epitope exhibits higher functional avidity but lesser cytolytic activity when compared with the anti-wild type response. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Keane, N.M., Laird, R., Chopra, A., Maiden, T., Almeida, C., Mallal, S. and John, M. (2008) HLA-Restricted T-cell responses to Immune-escape variants are detectable in chronic HIV-infection. In: AIDS Vaccine 2008, 13 - 16 October, Cape Town, South Africa.

Kulski, J.K., Shigenari, A., Shiina, T., Ota, M., Hosomichi, K., James, I. and Inoko, H. (2008) Human endogenous retrovirus (HERVK9) structural polymorphism with haplotypic HLA-A allelic associations. Genetics, 180 (1). pp. 445-457.

Lo, G., Herrmann, S., Cheng, W., Kontorinis, N., Phillips, E., Nolan, D. and Lucas, M. (2008) Screening for hepatocellular carcinoma (HCC) in hepatitis/HIV co-infection using ultrasound imaging and alfa-feto protein levels. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Mallal, S. (2008) Clinical applications of pharmacogenetics in HIV. In: Clinical Applications of Pharmacogenetics in HIV Symposium, 7 September 2008, Isla Verde, Puerto Rico.

Mallal, S. (2008) Futuristic forum for personalized infectious disease medicine. In: Futuristic Forum for Personalized Infectious Disease Medicine, 9 September 2008, Chapel Hill, USA.

Mallon, P.W.G., Sedwell, R., Rogers, G., Nolan, D., Unemori, P., Hoy, J., Samaras, K., Kelleher, A., Emery, S., Cooper, D.A. and Carr, A. (2008) Effect of rosiglitazone on peroxisome proliferator‐activated receptor γ gene expression in human adipose tissue is limited by antiretroviral drug–induced mitochondrial dysfunction. The Journal of Infectious Diseases, 198 (12). pp. 1794-1803.

Needham, M., Hooper, A., James, I., van Bockxmeer, F., Corbett, A., Day, T., Garlepp, M.J. and Mastaglia, F.L. (2008) Apolipoprotein ε alleles in sporadic inclusion body myositis: A reappraisal. Neuromuscular Disorders, 18 (2). pp. 150-152.

Needham, M., James, I., Corbett, A., Day, T., Christiansen, F., Phillips, B. and Mastaglia, F.L. (2008) Sporadic inclusion body myositis: Phenotypic variability and influence of HLA-DR3 in a cohort of 57 Australian cases. Journal of Neurology, Neurosurgery & Psychiatry, 79 (9). pp. 1056-1060.

Pfafferott, K., Gaudieri, S., Naidoo, K., Rauch, A., Baccala, M., Baker, R., Mallal, S. and Lucas, M. (2008) Population based genetic approach identifies novel hepatitis C targets of the immune response. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia.

Pfafferott, K., Ulsenheimer, A., Naidoo, K., Rauch, A., Gaudieri, S., Mallal, S., Diepolder, H.M. and Lucas, M. (2008) Changes in HCV dynamics due to immune pressure during early and late infection. In: Australian Centre for HIV and Hepatitis Virology Research (ACH2) 4th Annual Workshop, 4 - 6 June 2008, Novotel Barossa Valley Resort, South Australia.

Price, P., Fernandez, S., Tan, D.B.A., James, I.R., Keane, N.M. and French, M.A. (2008) Nadir CD4 T-cell counts continue to influence interferon-γ responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency. JAIDS Journal of Acquired Immune Deficiency Syndromes, 49 (4). pp. 462-464.

Rauch, A., Nolan, D., Furrer, H., McKinnon, E., John, M., Mallal, S., Gaudieri, S., Günthard, H.F., Schmid, P., Battegay, M., Hirschel, B., Telenti, A., James, I. and Swiss HIV Cohort Study, . (2008) HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy. Clinical Infectious Diseases, 46 (12). pp. 1921-1925.

Rauch, A., Nolan, D., Thurnheer, C., Fux, C.A., Cavassini, M., Chave, J-P, Opravil, M., Phillips, E., Mallal, S. and Furrer, H. (2008) Refining abacavir hypersensitivity diagnoses using a structured clinical assessment and genetic testing in the Swiss HIV Cohort Study. Antiviral Therapy, 13 (8). pp. 1019-1028.

Rauch, A., Thurnheer, C., Fux, C., Nolan, D. and Mallal, S. (2008) Genetic testing and a structured clinical assessment reveal overdiagnosis of abacavir hypersensitivity reactions in the Swiss HIV Cohort study. In: 12th International Workshop on HIV Observational Databases, 27 - 30 March 2008, Malaga, Spain.

Saag, M., Balu, R., Phillips, E.J., Brachman, P., Martorell, C., Burman, W., Stancil, B., Mosteller, M., Brothers, C., Wannamaker, P., Hughes, A., Sutherland‐Phillips, D., Mallal, S. and Shaefer, M. (2008) High sensitivity of human leukocyte antigen–B*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients. Clinical Infectious Diseases, 46 (7). pp. 1111-1118.

Tan, D.B.A., Yong, Y.K., Tan, H.Y., Kamarulzaman, A., Tan, L.H., Lim, A., James, I., French, M. and Price, P. (2008) Immunological profiles of immune restoration disease presenting as mycobacterial lymphadenitis and cryptococcal meningitis. HIV Medicine, 9 (5). pp. 307-316.

Tschochner, M., Chopra, A., Ahmad, I., Fordham, M., Mallal, S. and John, M. (2008) Naturally occurring polymorphisms in HIV-1 integrase: Relationship to HIV subtype, integrase inhibitor resistance and immune selection. In: 20th Annual Australasian Society for HIV Medicine Conference, 17 - 20 September, Perth, Western Australia

Wannamaker, P., Mallal, S., Phillips, E., Young, B., Brothers, C., Sutherland-Phillips, D., Thorborn, D. and Shaefer, M. (2008) HLA-B*5701 screening reduces abacavir hypersensitivity reactions (ABC HSR): Multiple lines of evidence to establish a new standard of care. In: 18th International AIDS Conference, 3 - 8 August 2008, Mexico City, Mexico.

2007

Bowyer, S., Ulsenheimer, A., Lucas, M., Pfafferott, K., Heeg, M., Gaudieri, S., Grüner, N., Rauch, A., Gerlach, J.T., Jung, M.C., Zachoval, R., Pape, G.R., Schraut, W., Santantonio, T., Nitschko, H., Obermeier, M., Phillips, R., Scriba, T.J., Semmo, N., Day, C., Weber, J.N., Fidler, S., Thimme, R., Haberstroh, A., Baumert, T.F., Klenerman, P. and Diepolder, H.M. (2007) Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection. PLoS ONE, 2 (7). e649.

Chopra, A., Laird, R., Choo, L., Patterson, A., Sutton, K., Mamotte, C. and Mallal, S. (2007) Development of a high throughput DNA extraction system and its application to HLA typing. In: 31st Annual Scientific Meeting of the Australasian and South East Asian Tissue Typing Association (ASEATTA) 2007, 14 - 16 November 2007, Fremantle, WA.

D'Orsogna, L.J., Krueger, R.G., McKinnon, E.J. and French, M.A. (2007) Circulating memory B-cell subpopulations are affected differently by HIV infection and antiretroviral therapy. AIDS, 21 (13). pp. 1747-1752.

Fellay, J., Shianna, K.V., Ge, D., Colombo, S., Ledergerber, B., Weale, M., Zhang, K., Gumbs, C., Castagna, A., Cossarizza, A., Cozzi-Lepri, A., De Luca, A., Easterbrook, P., Francioli, P., Mallal, S., Martinez-Picado, J., Miro, J.M., Obel, N., Smith, J. P., Wyniger, J., Descombes, P., Antonarakis, S.E., Letvin, N.L., McMichael, A.J., Haynes, B.F., Telenti, A. and Goldstein, D.B. (2007) A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1. Science, 317 (5840). pp. 944-947.

Frahm, N., Yusim, K., Suscovich, T.J., Adams, S., Sidney, J., Hraber, P., Hewitt, H.S., Linde, C.H., Kavanagh, D.G., Woodberry, T., Henry, L.M., Faircloth, K., Listgarten, J., Kadie, C., Jojic, N., Sango, K., Brown, N.V., Pae, E., Zaman, M.T., Bihl, F., Khatri, A., John, M., Mallal, S., Marincola, F.M., Walker, B.D., Sette, A., Heckerman, D., Korber, B.T.M. and Brander, C. (2007) Extensive HLA class I allele promiscuity among viral CTL epitopes. European Journal of Immunology, 37 (9). pp. 2419-2433.

Gaudieri, S., Rauch, A., Park, L.P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Naidoo, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2007) Erratum: Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection (Journal of Virology (2006) 80, 22, (11094-11104)). Journal of Virology, 81 (16). pp. 8846-8848.

Hammond, E., Almeida, C.M., Mamotte, C., Nolan, D., Phillips, E.J., Schollaardt, T.A., Gill, M.J., Angel, J.B., Neurath, D., Li, J., Giulivi, T., McIntyre, C., Koultchitski, G., Wong, B., Reis, M., Rachlis, A., Cole, D., Chew, C.B., Neifer, S., Lalonde, R., Roger, M., Jeanneau, A. and Mallal, S. (2007) External quality assessment of HLA-B*5701 reporting: an international multicentre survey. Antiviral Therapy, 12 (7). pp. 1027-1032.

Hammond, E., Mamotte, C., Nolan, D. and Mallal, S. (2007) HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay. Tissue Antigens, 70 (1). pp. 58-61.

Hammond, E. and Nolan, D. (2007) Adipose tissue inflammation and altered adipokine and cytokine production in antiretroviral therapy-associated lipodystrophy (Review). Current Opinion in HIV and AIDS, 2 (4). pp. 274-281.

Hammond, E., Shaw, K., Carnley, B., P'ng, S., James, I. and Herrmann, R. (2007) Quantitative determination of JAK2 V617F by TaqMan: An absolute measure of averaged copies per cell that may be associated with the different types of myeloproliferative disorders. The Journal of Molecular Diagnostics, 9 (2). pp. 242-248.

Hammond, E., Shaw, K. and Herrmann, R. (2007) The JAK2 V617F mutation is detectable in granulocyte populations at greater than two copies per cell among individuals with myeloproliferative disorders [3] (letter). Leukemia, 21 (4). pp. 815-816.

Hammond, E., Shaw, K. and Herrmann, R. (2007) “The JAK2 V617F mutation is detectable in granulocyte populations at greater than two copies per cell among individuals with myeloproliferative disorders”, by El Housni et al.[5] (letter). Leukemia, 21 (4). pp. 817-818.

Harari, A., Cellerai, C., Enders, F.B., Kostler, J., Codarri, L., Tapia, G., Boyman, O., Castro, E., Gaudieri, S., James, I., John, M., Wagner, R., Mallal, S. and Pantaleo, G. (2007) Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proceedings of the National Academy of Sciences, 104 (41). pp. 16233-16238.

Herrmann, S., McKinnon, E., John, M., Hyland, N., Martinez, O.P., Cain, A., Turner, K., Coombs, A., Manolikos, C. and Mallal, S. (2007) Evidence-based, multifactorial approach to addressing non-adherence to antiretroviral therapy and improving standards of care. Internal Medicine Journal, 38 (1). pp. 8-15.

Herrmann, S.E., McKinnon, E., John, M. and Mallal, S. (2007) Influence of dosing regimen on adherence to antiretroviral therapy within PI and NNRTI regimens. In: 4th International AIDS Conference on HIV Pathogenesis, Treatment and Prevention, 22 - 25 July, Sydney, Australia

John, M., Heckerman, D., Park, L. and Mallal, S. (2007) Strong genome-wide HLA-associated selection evident in HIV-1 in a national contemporary US population: The ACTG 5142 study. In: AIDS Vaccine 2007, 20 - 23 August 2007, Seattle, Washington, USA.

Langan, L.L., Park, L.P., Hughes, T.L., Irish, A., Luxton, G., Witt, C.S. and Christiansen, F.T. (2007) Post-Transplant HLA class II Antibodies and High Soluble CD30 Levels are Independently Associated with Poor Kidney Graft Survival. American Journal of Transplantation, 7 (4). pp. 847-856.

Lim, A., Tan, D.B.A., Price, P., Kamarulzaman, A., Tan, H.Y., James, I. and French, M.A. (2007) Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy. AIDS, 21 (12). pp. 1525-1534.

Lucas, A., Nolan, D. and Mallal, S. (2007) HLA-B*5701 screening for susceptibility to abacavir hypersensitivity. Journal of Antimicrobial Chemotherapy, 59 (4). pp. 591-593.

Mallal, S. and Phillips, E. (2007) Introduction of pharmacogenetic screening to HIV clinical practice: Potential benefits and challenges. European Infectious Diseases (2). pp. 13-18.

Martin, A., Almeida, C.M., Cameron, P.U., Purcell, Anthony W, Nolan, D., James, I., McCluskey, J., Phillips, E.J., Landay, Alan and Mallal, S. (2007) Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS, 21 (10). pp. 1233-1244.

McKinnon, E., John, M., Herrmann, S.E. and James, I. (2007) Models and analysis of point-inflated data in a study of markers of HAART efficacy. In: 11th International Workshop on HIV Observational Databases, 22 - 25 March, Monte Carlo.

Nolan, D. (2007) The view from Sydney: 9th International Lipodystrophy Workshop. Nutrition and Metabolic Disorders in HIV Infection, 6 (3). pp. 1161-1164.

Nolan, D., Almeida, C. and Phillips, E.J. (2007) Abacavir hypersensitivity. In: Pichler, W., (ed.) Drug Hypersensitivity. S. Karger AG, Basel, Switzerland, pp. 116-125.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2007) Erratum: Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation (Journal of Virology (2006) 80, 18, (9259-9269)). Journal of Virology, 81 (16). pp. 8843-8845.

Patterson, A., Sutton, K., Laird, R., Choo, L., Denholm, S., Chopra, A., Lucas, A., Nolan, D., John, M., Gaudieri, S. and Mallal, S. (2007) HLA genotyping for Population-based pathogen and disease associations research. In: 31st Annual Scientific Meeting of the Australasian and South East Asian Tissue Typing Association (ASEATTA) 2007, 14 - 16 November 2007, Fremantle, WA.

Phillips, E.J. and Mallal, S. (2007) Drug hypersensitivity in HIV. Current Opinion in Allergy and Clinical Immunology, 7 (4). pp. 324-330.

Pocathikorn, A., Taylor, R.R., James, I. and Mamotte, C.D.S. (2007) LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism. Journal of Nutrition, 137 (9). pp. 2062-2067.

Rauch, A., Laird, R., McKinnon, E., Telenti, A., Furrer, H., Weber, R., Smillie, D. and Gaudieri, S. (2007) Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection. Tissue Antigens, 69 (SUPPL. 1). pp. 237-240.

Wu, J.H.Y., Ward, N.C., Indrawan, A.P., Almeida, C.M., Hodgson, J.M., Proudfoot, J.M., Puddey, I.B. and Croft, K.D. (2007) Effects of -Tocopherol and Mixed Tocopherol Supplementation on Markers of Oxidative Stress and Inflammation in Type 2 Diabetes. Clinical Chemistry, 53 (3). pp. 511-519.

2006

Almeida, C., Mamotte, C., Nolan, D., Martin, A., Hammond, E. and Mallal, S. (2006) Investigation of the sensitivity and specificity of the HLA-B*5701 genotyping assay. In: Pharmacogenetics Meeting in Colds Spring Harbour, 10 - 15 November 2006, New York, U.S.A.

Burgess, K., Price, P., James, I.R., Stone, S.F., Keane, N.M., Lim, A.Y.F., Warmington, J.R. and French, M.A. (2006) Interferon-Gamma responses to candida recover slowly or remain low in immunodeficient HIV patients responding to ART. Journal of Clinical Immunology, 26 (2). pp. 160-167.

Fernandez, S., Price, P., McKinnon, E.J., Nolan, R.C. and French, M.A. (2006) Low CD4+ T-cell counts in HIV patients receiving effective antiretroviral therapy are associated with CD4+ T-cell activation and senescence but not with lower effector memory T-cell function. Clinical Immunology, 120 (2). pp. 163-170.

Fernandez, S., Rosenow, A.A., James, I.R., Roberts, S.G., Nolan, R.C., French, M.A. and Price, P. (2006) Recovery of CD4+ T Cells in HIV Patients With a Stable Virologic Response to Antiretroviral Therapy Is Associated With Polymorphisms of Interleukin-6 and Central Major Histocompatibility Complex Genes. JAIDS Journal of Acquired Immune Deficiency Syndromes, 41 (1). pp. 1-5.

Frahm, N., Kiepiela, P., Adams, S., Linde, C.H., Hewitt, H.S., Sango, K., Feeney, M.E., Addo, M.M., Lichterfeld, M., Lahaie, M.P., Pae, E., Wurcel, A.G., Roach, T., St John, M.A., Altfeld, M., Marincola, F.M., Moore, C., Mallal, S., Carrington, M., Heckerman, D., Allen, T.M., Mullins, J.I., Korber, B.T., Goulder, P.J.R., Walker, B.D. and Brander, C. (2006) Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nature Immunology, 7 (2). pp. 173-178.

Gaudieri, S., Rauch, A., Naidoo, K., Park, P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2006) Evidence of viral adaptation to HLA Class I-restricted immune pressure in chronic Hepatitis C virus infection. In: 13th International Meeting on Hepatitis C Virus & Related Viruses, 27 - 31 August, Cairns, Australia.

Gaudieri, S., Rauch, A., Park, L.P., Freitas, E., Herrmann, S., Jeffrey, G., Cheng, W., Pfafferott, K., Naidoo, K., Chapman, R., Battegay, M., Weber, R., Telenti, A., Furrer, H., James, I., Lucas, M., Mallal, S.A. and Swiss HIV Cohort Study, (2006) Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection. Journal of Virology, 80 (22). pp. 11094-11104.

Hammond, E. (2006) Review of the 7th International Workshop on adverse reactions and lipodystrophy in HIV. Dublin 2005 (Review). Nutrition and Metabolic Disorders in HIV Infection, 5 (1). pp. 899-908.

Hammond, E., Nolan, D., McKinnon, E., Pace, C. and Mallal, S. (2006) Assessing the risk of adipose tissue mitochondrial toxicity in HIV-infected individuals on contemporary NRTI regimens. In: 8th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 23 - 26 September 2006, San Fransisco, U.S.A.

Mallal, S. (2006) HCV and HIV adaptation to polymorphic host defenses: Parallels and differences. In: 13th International Meeting on Hepatitis C Virus & Related Viruses, 27 - 31 August 2006, Cairns, Australia.

Mallal, S. (2006) Host genetics unplugged: Removing the camouflage of viral adaptation. Current Opinion in HIV and AIDS, 1 (3). pp. 218-219.

Martin, A., Nolan, D., Almeida, C., Rauch, A. and Mallal, S. (2006) Predicting and diagnosing abacavir and nevirapine drug hypersensitivity: from bedside to bench and back again. Pharmacogenomics, 7 (1). pp. 15-23.

Martins, I.J., Hone, E., Foster, J.K., S, S.I., Gnjec, A., Fuller, S.J., Nolan, D., Gandy, S.E. and Martins, R.N. (2006) Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Molecular Psychiatry, 11 (8). pp. 721-736.

Nolan, D., Gaudieri, S. and Mallal, S. (2006) Host genetics and viral infections: Immunology taught by viruses, virology taught by the immune system. Current Opinion in Immunology, 18 (4). pp. 413-421.

Nolan, D., Phillips, E. and Mallal, S. (2006) Efavirenz and CYP2B6 polymorphism: Implications for drug toxicity and resistance. Clinical Infectious Diseases, 42 (3). pp. 408-410.

Pace, C., Keller, J., Nolan, D., James, I., Gaudieri, S., Moore, C. and Mallal, S. (2006) Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation. Journal of Virology, 80 (18). pp. 9259-9269.

Pace, C., Nolan, D. and Mallal, S. (2006) Investigation of deoxythymidylate kinase genetic variation and its influence on haematological response to zidovudine treatment. In: 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20 - 22 April 2006, Lisbon, Portugal.

Phillips, E., Rauch, A., Nolan, D., Martin, A., Almeida, C., Knowles, S., Shear, N., Harris, N., Montaner, J.S.G. and Mallal, S. (2006) Pharmacogenetics and clinical characteristics of patch test confirmed patients with Abacavir hypersensitivity. In: 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20 - 22 April 2006, Lisbon, Portugal.

Phillips, E.J., Larsen, G., Brumme, Z., Harris, M., Toy, J., Harrigan, R., Mallal, S. and Montaner, J.S.G. (2006) Abacavir patch testing and rechallenge in patients labeled with abacavir hypersensitivity syndrome. In: 2nd International Drug Hypersensitivity Conference, 18 - 21 April 2006, Liverpool, England.

Price, P., Keane, N.M., Lee, S., Lim, A.F.Y., McKinnon, E.J. and French, M.A. (2006) A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to antiretroviral therapy. Immunology, 119 (1). pp. 74-82.

2005

Allen, T., Altfield, M., Geer, S., Kalife, E., Moore, C., O'Sullivan, K., DeSouza, I., Kaufmann, D., Lahaie, M., Reyor, L., Brander, C., Jessen, H., Rosenberg, E., Mallal, S. and Walker, B. (2005) Stereotypic escape from CD8+ T-cell responses represents a major driving force of HIV-1 sequence diversity and reveals constraints on HIV-1 evolution. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA

Allen, T.M., Altfeld, M., Geer, S.C., Kalife, E.T., Moore, C., O'Sullivan, K.M., DeSouza, I., Feeney, M.E., Eldridge, R.L., Maier, E.L., Kaufmann, D.E., Lahaie, M.P., Reyor, L., Tanzi, G., Johnston, M.N., Brander, C., Draenert, R., Rockstroh, J.K., Jessen, H., Rosenberg, E.S., Mallal, S.A. and Walker, B.D. (2005) Selective escape from CD8+ T-Cell responses represents a major driving force of Human Immunodeficiency Virus Type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution. Journal of Virology, 79 (21). pp. 13239-13249.

Allen, T.M., Yu, X.G., Kalife, E.T., Reyor, L.L., Lichterfeld, M., John, M., Cheng, M., Allgaier, R.L., Mui, S., Frahm, N., Alter, G., Brown, N.V., Johnston, M.N., Rosenberg, E.S., Mallal, S.A., Brander, C., Walker, B.D. and Altfeld, M. (2005) De Novo generation of escape Variant-specific CD8+ T-Cell responses following Cytotoxic T-Lymphocyte escape in chronic Human Immunodeficiency Virus Type 1 Infection. Journal of Virology, 79 (20). pp. 12952-12960.

Almeida, C., Martin, A., Nolan, D., Cameron, P., James, I., Mifsud, N., Purcell, A., McCluskey, J. and Mallal, S. (2005) Chronic in vitro abacavir exposure elicits an immunological response in abacavir naive HIV positive individuals. In: 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment, 24 - 27 July 2005, Rio de Janeiro, Brazil.

Balakrishnan, K., Verdile, G., Mehta, P.D., Beilby, J., Nolan, D., Galvão, D.A., Newton, R., Gandy, S.E. and Martins, R.N. (2005) Plasma Aβ42 correlates positively with increased body fat in healthy individuals. Journal of Alzheimer's disease : JAD, 8 (3). pp. 269-282.

Christiansen, F.T., Martin, A.M., Nolan, D.A., Gaudieri, S., Almeida, C., Phillips, E., Cameron, P.U., Moore, C.B., James, I. and Mallal, S.A. (2005) Host MHC influences susceptibility to hypersensitivity reactions to two drugs commonly used in HIV therapy. In: XIX European Immunogenetics & Histocompatibility Conference, 23 - 26 April 2005, Istanbul, Turkey.

Feeney, M.E., Tang, Y., Pfafferott, K., Roosevelt, K.A., Draenert, R., Trocha, A., Yu, X.G., Verrill, C., Allen, T., Moore, C., Mallal, S., Burchett, S., McIntosh, K., Pelton, S.I., St. John, M.A., Hazra, R., Klenerman, P., Altfeld, M., Walker, B.D. and Goulder, P.J.R. (2005) HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response. Journal of Immunology, 174 (12). pp. 7524-7530.

Gaudieri, S., DeSantis, D., McKinnon, E., Moore, C., Nolan, D., Witt, C.S., Mallal, S.A. and Christiansen, F.T. (2005) Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes and Immunity, 6 (8). pp. 683-690.

Gaudieri, S., Lucas, M., Freitas, E., Moore, C., Jeffrey, G., John, M., Cheng, W., Herrmann, S., Naidoo, V. and Mallal, S. (2005) Adaptation of Hepatitis C virus to HLA-restricted responses in an Australian host population. In: 2nd National Scientific Workshop 2005, 4 - 6 May 2005, Terrigal, N.S.W.

Gaudieri, S., Lucas, M., Freitas, E., Naidoo, K., Park, L., Pfafferott, K., Moore, C., Jeffrey, G., Cheng, W., Rauch, A., Herrmann, S. and Mallal, S. (2005) Adaptation of Hepatitis C virus to HLA-restricted responses in an Australian host population. In: 12th International Symposium on Hepatitis C and Related Viruses, 2 - 6 October, Montreal, Canada.

Gaudieri, S., Nolan, D., McKinnon, E., Witt, C.S., Mallal, S. and Christiansen, F.T. (2005) Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responses. Molecular Immunology, 42 (4). pp. 557-560.

Gillett, M.J., Cameron, P.U., Nguyen, H.V., Hurley, D.M. and Mallal, S.A. (2005) Iatrogenic Cushingʼs syndrome in an HIV-infected patient treated with ritonavir and inhaled fluticasone. AIDS, 19 (7). pp. 740-741.

Hammond, E., Nolan, D., McKinnon, E., Pace, C., Metcalf, C. and Mallal, S. (2005) Assessing the contribution of ART, HIV and host factors to adipose tissue changes occurring in HIV-infected individuals: Risk profile for lipoatrophy. In: 7th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 16 November 2005, Dublin, Ireland

James, I., McKinnon, E., John, M. and Mallal, S. (2005) Association of HLA-Bw4 with post-HAART outcomes. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

John, M. and Mallal, S. (2005) CTL responses to HIV and SIV: wrestling with smoke. Nature Immunology, 6 (3). pp. 232-234.

John, M., Moore, C.B., James, I.R. and Mallal, S.A. (2005) Interactive selective pressures of HLA-restricted immune responses and antiretroviral drugs on HIV-1. Antiviral Therapy, 10 . pp. 551-555.

Jojic, V., Jojic, N., Heckerman, D., Kadie, C., Meek, C., Moore, C., John, M. and Mallal, S. (2005) HLA-driven optimization of an HIV vaccine immunogen. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Leslie, A., Kavanagh, D., Honeyborne, I., Pfafferott, K., Edwards, C., Pillay, T., Hilton, L., Thobakgale, C., Ramduth, D., Draenert, R., Le Gall, S., Luzzi, G., Edwards, A., Brander, C., Sewell, A.K., Moore, S., Mullins, J., Moore, C., Mallal, S., Bhardwaj, N., Yusim, K., Phillips, R., Klenerman, P., Korber, B., Kiepiela, P., Walker, B. and Goulder, P. (2005) Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. Journal of Experimental Medicine, 201 (6). pp. 891-902.

Lucas, A.D., Gaudieri, S., Rauch, A., Nolan, D. and Mallal, S. (2005) Cellular tropism of HIV-1 mediated and contrained by coreceptor dependencies. Journal of Viral Entry, 1 (1). pp. 17-27.

Mallal, S. (2005) Role of NRTI-induced adipocyte mtDNA depletion of lipoatrophy. In: 1st Meeting on Mitochondrial Toxicity and HIV infection: Understanding the Pathogenesis for a Therapeutic Approach, 19 - 21 May 2005, Modena, Italy.

Mallal, S., Pace, C., Nolan, D., Keller, J., Moore, C., Carvalho, F., Patterson, A., Sutton, K. and Gaudieri, S. (2005) Analysis of HIV-1 hypermutation and its relationship with APOBEC3G and vif genetic variation in vivo. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Mallon, P., Sedwell, R., Rogers, G., Nolan, D., Unemori, P., Wand, H., Samaras, K., Kelleher, A., Emery, S., Cooper, D., Carr, A. and Mallal, S. (2005) The effect of rosiglitazone on PPARg expression in human adipose tissue Is limited by continued exposure to thymidine NRTI. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Martin, A., Almeida, C., Nolan, D., Cameron, P., James, I., Purcell, T., McCluskey, J., Phillips, E. and Mallal, S. (2005) Abacavir stimulates Hsp70 redistribution in Antigen-presenting cells of patients with hypersensitivity: Association with Type-I alcohol dehydrogenase activity. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Martin, A., Almeida, C., Purcell, A., McCluskey, J., Phillips, E. and Mallal, S. (2005) Pathogenesis of abacavir hypersensitivity mediated via stimulation of the innate and adaptive immune systems. In: Gordon Conference on Adverse Drug Reactions, 5 - 10 June 2005, Connecticut College, New London, CT.

Martin, A.M., Almeida, C., Nolan, D. and Mallal, S. (2005) TLR2 and CD14 receptors are essential for abacavir induced HSP70 signalling and dendritic cell activation. In: ANS Apoptosis and Immunity 2005, 31 May 2005, Cairns, Australia.

Martin, A.M., Almeida, C., Nolan, D., Purcell, A., McCluskey, J., Phillips, E. and Mallal, S. (2005) Both the innate and adaptive immune systems are important in the pathogenesis of abacavir hypersensitivity reaction. In: Gordon Research Conference on Adverse Drug Reactions, 5 - 10 June 2005, New London, CT.

Martin, A.M., Nolan, D., James, I., Cameron, P., Keller, J., Moore, C., Phillips, E., Christiansen, F.T. and Mallal, S. (2005) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS, 19 (1). pp. 97-99.

Martin, A.M., Nolan, D. and Mallal, S. (2005) HLA-B*5701 typing by sequence-specific amplification: validation and comparison with sequence-based typing. Tissue Antigens, 65 (6). pp. 571-574.

McKinnon, E., James, I., Lucas, M. and Mallal, S. (2005) Differential influence of age on maximal immune response to HAART. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

McKinnon, E., Lucas, M., French, M., James, I. and Mallal, S. (2005) Differential influence of age on CD4 T-cell response to HAART. In: 9th International Workshop on HIV Observational Databases, 21 - 24 April 2005, Budapest, Hungary.

Nolan, D. (2005) Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy? Drug Safety, 28 (12). pp. 1069-1074.

Nolan, D., James, I. and Mallal, S. (2005) HIV/AIDS: HIV: Experiencing the pressures of modern life. Science, 307 (5714). pp. 1422-1424.

Nolan, D. and Mallal, S. (2005) Antiretroviral-therapy-associated lipoatrophy: current status and future directions. Sexual Health, 2 (3). pp. 153-163.

Nolan, D., Reiss, P. and Mallal, S. (2005) Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert Opinion on Drug Safety, 4 (2). pp. 201-218.

Park, L., Goulder, P., Kiepiela, P., Brander, C., Walker, B., Korber, B., Szinger, J., Keller, J., John, M., Nolan, D. and Mallal, S. (2005) HLA-restricted immune responses have driven the evolution of HIV-1 clades. In: 12th Conference on Retroviruses and Opportunistic Infections, 22 - 25 February 2005, Hynes Convention Center, Boston, MA.

Petoumenos, K., Ringland, C., Goodman, R., Gotowski, M., Couldwell, D., Lewis, L., Austin, D., Block, M., Quan, D., Gowers, A., Brown, K.R., Skobalj, N. and Mallal, S. (2005) Antiretroviral treatment change among HIV, hepatitis B virus and hepatitis C virus co-infected patients in the Australian HIV Observational Database. HIV Medicine, 6 (3). pp. 155-163.

Phillips, E.J., Wong, G., Kaul, R., Shahabi, K., Nolan, D., Knowles, S.R., Martin, A.M., Mallal, S. and Shear, N.H. (2005) Clinical and immunogenetic correlates of abacavir hypersensitivity. AIDS, 19 (9). pp. 979-981.

Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C. and Mallal, S. (2005) Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV Cohort. In: 7th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 16 November 2005, Dublin, Ireland.

Redgrave, B.E., Stone, S.F., French, M.A.H., Krueger, R., James, I.R. and Price, P. (2005) The effect of combination antiretroviral therapy on CD5 B- cells, B-cell activation and hypergammaglobulinaemia in HIV-1-infected patients. HIV Medicine, 6 (5). pp. 307-312.

Rushbrook, S.M., Ward, S.M., Unitt, E., Vowler, S.L., Lucas, M., Klenerman, P. and Alexander, G.J.M. (2005) Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. Journal of Virology, 79 (12). pp. 7852-7859.

Vidal, F., Peraire, J., Domingo, P., Broch, M., Knobel, H., Pedrol, E., Dalmau, D., Viladés, C., Sambeat, M.A., Gutiérrez, C., Richart, C. and Mallal, S. (2005) Lack of association of SDF-1 3'A variant allele with long-term nonprogressive HIV-1 infection is extended beyond 16 years. JAIDS Journal of Acquired Immune Deficiency Syndromes, 40 (3). pp. 276-279.

Vidal, F., Viladés, C., Domingo, P., Broch, M., Pedrol, E., Dalmau, D., Knobel, H., Peraire, J., Gutiérrez, C., Sambeat, M., Fontanet, À., Deig, E., Cairó, M., Montero, M., Richart, C. and Mallal, S. (2005) Spanish HIV-1-infected long-term nonprogressors of more than 15 years have an increased frequency of the CX3CR1 249I variant allele. JAIDS Journal of Acquired Immune Deficiency Syndromes, 40 (5). pp. 527-531.

2004

Allen, T.M., Altfeld, M., Yu, X.G., O'Sullivan, K.M., Lichterfeld, M., Le Gall, S., John, M., Mothe, B.R., Lee, P.K., Kalife, E.T., Cohen, D.E., Freedberg, K.A., Strick, D.A., Johnston, M.N., Sette, A., Rosenberg, E.S., Mallal, S.A., Goulder, P.J.R., Brander, C. and Walker, B.D. (2004) Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in Human Immunodeficiency Virus Type 1 infection. Journal of Virology, 78 (13). pp. 7069-7078.

Almeida, C., Martin, A., Nolan, D. and Mallal, S. (2004) Increase in inflammatory cytokine levels in abacavir stimulated mononuclear cells from HIV infected patients with abacavir hypersensitivity. In: 16th Annual Conference of the Australasian Society for HIV Medicine , 2 - 4 September 2004, Canberra, Australia

Burkhardt, M.S., Foster, J.K., Laws, S.M., Baker, L.D., Craft, S., Gandy, S.E., Stuckey, B.G.A., Clarnette, R., Nolan, D., Hewson-Bower, B. and Martins, R.N. (2004) Oestrogen replacement therapy may improve memory functioning in the absence of APOE e4. Journal of Alzheimer's disease : JAD, 6 (3). pp. 221-228.

Christiansen, F.T., Gaudieri, S., De Santis, D., McKinnon, E., Moore, C., Nolan, D. and Mallal, S. (2004) NK receptor haplotypes and HLA as predictors of HIV-1 progression. In: NK2004 Workshop, 24 - 28 April 2004, Noordwijkerhout, The Netherlands.

Gaudieri, S., Freitas, E., Moore, C., Jeffrey, G., Lucas, M., John, M., Cheng, W., Herrmann, S., D'Aquila, R. and Mallal, S. (2004) Adaptation of hepatitis C virus to HLA-restricted responses in HLA diverse populations. In: 4th Australasian Hepatitis C Conference, 31 August - 2 September 2004, Canberra, Australia.

Gaudieri, S., Freitas, E., Moore, C., Lucas, M., Jeffrey, G., Cheng, W., John, M. and Mallal, S. (2004) Adaptation of Hepatitis C virus to HLA-restricted responses in HLA diverse populations. In: 11th International Symposium on Hepatitis C and Related Diseases, 3 - 7 October 2004, Heidelberg, Germany.

Hammond, E., Nolan, D., James, I., McKinnon, E. and Mallal, S. (2004) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipoatrophy in HIV infected patients: A model of drug induced mitochondrial toxicity. In: Mitochodrial Medicine 2004, 4 - 8 August 2004, Pittsburgh, PA.

Hammond, E., Nolan, D., James, I., Metcalf, C. and Mallal, S. (2004) Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6-12 months of commencing nucleoside reverse transcriptase inhibitor therapy. AIDS, 18 (5). pp. 815-817.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2004) Differential effects of nucleoside reverse transcriptase inhibitor (NRTI) regimens on adipocyte mitochondrial DNA depletion in HIV-infected patients. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

Herrmann, S., McKinnon, E. and Mallal, S. (2004) Combining adherence monitoring with patient education in the Royal Perth Hospital Immunology Outpatient Clinic. In: 16th Annual Conference of the Australasian Society for HIV Medicine, 2 - 4 September, Canberra, Australia.

Keane, N.M., Price, P., Lee, S., Almeida, C.A., Stone, S.F., James, I. and French, M.A. (2004) Restoration of CD4 T-cell responses to cytomegalovirus is short-lived in severely immunodeficient HIV-infected patients responding to highly active antiretroviral therapy. HIV Medicine, 5 (6). pp. 407-414.

Kiepiela, P., Leslie, A.J., Honeyborne, I., Ramduth, D., Thobakgale, C., Chetty, S., Rathnavalu, P., Moore, C.B., Pfafferott, K.J., Hilton, L., Zimbwa, P., Moore, S., Allen, T., Brander, C., Addo, M.M., Altfeld, M., James, I., Mallal, S., Bunce, M., Barber, L.D., Szinger, J., Day, C., Klenerman, P., Mullins, J., Korber, B., Coovadia, H.M., Walker, B.D. and Goulder, P.J.R. (2004) Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature, 432 (7018). pp. 769-775.

Mallal, S., Almeida, C., Nolan, D. and Martin, A. (2004) Abacavir hypersensitivity as a model for elucidating Class I-restricted drug reactions. In: 7th International Meeting of the International Society for the Study of Xenobiotics, 29 August - 2 September 2004, Vancouver, Canada.

Martin, A., Cameron, P., Nolan, D., James, I., Keller, J., Phillips, E. and Mallal, S. (2004) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*01 and higher CD4+ T cell counts. In: XV International AIDS Conference, 11 - 16 July 2004, Bangkok, Thailand.

Martin, A.M., Almeida, C., Nolan, D., Gaudieri, S., James, I., Christiansen, F.T., Purcell, A., McCluskey, J. and Mallal, S. (2004) Carriage of HLA-B*5701 and a haplotypic Hsp70-Hom variant is associated with a Class I MHC-restricted hypersensitivity response to abacavir. In: 11th Conference on Retroviruses and Opportunistic Infections, 8 - 11 February 2004, Washington DC, U.S.A.

Martin, A.M., Kulski, J.K., Gaudieri, S., Witt, C.S., Freitas, E.M., Trowsdale, J. and Christiansen, F.T. (2004) Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B. Gene, 335 . pp. 121-131.

Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., James, I., Phillips, E. and Mallal, S. (2004) Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences, 101 (12). pp. 4180-4185.

Martin, A.M., Nolan, D., Gaudieri, S., Phillips, E. and Mallal, S. (2004) Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity. Pharmacogenomics, 5 (6). pp. 643-655.

Martin, A.M., Smith, D., Carr, A., Hoy, J., Chuah, J., Mallal, S., Law, M., Clements, M. and Cooper , D.A. (2004) Progression of Lipodystrophy (LD) with continued thymidine analogue usage: Long-term Follow-Up from a randomized clinical trial (The PIILR Study). HIV Clinical Trials, 5 (4). pp. 192-200.

McKinnon, E., James, I. and Mallal, S. (2004) Assessment of virological control in patients with HIV undergoing HAART. In: 8th International Workshop on HIV Observational Databases, 25 - 28 March 2004, Montreux, Switzerland.

Nolan, D., Gaudieri, S., John, M. and Mallal, S. (2004) Impact of host genetics on HIV disease progression and treatment: New conflicts on an ancient battleground. AIDS, 18 (9). pp. 1231-1240.

Nolan, D. and Mallal, S. (2004) Complications associated with NRTI therapy: Update on clinical features and possible pathogenic mechanisms. Antiviral Therapy, 9 (6). pp. 849-863.

Nolan, D. and Mallal, S. (2004) The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome. Journal of HIV Therapy, 9 (2). pp. 34-40.

Nolan, D. and Pace, C. (2004) Potential roles for uncoupling proteins in HIV lipodystrophy. Mitochondrion, 4 (2-3). pp. 185-191.

Price, P., James, I., Fernandez, S. and French, M.A. (2004) Alleles of the gene encoding IL-1?? may predict control of plasma viraemia in HIV-1 patients on highly active antiretroviral therapy. AIDS, 18 (11). pp. 1495-1501.

Windsor, L., Morahan, G., Huang, D., McCann, V., Jones, T., James, I., Christiansen, F.T. and Price, P. (2004) Alleles of the IL12B 3′UTR associate with late onset of type 1 diabetes. Human Immunology, 65 (12). pp. 1432-1436.

Wong, G., Kaul, R., Shahabi, K., Nolan, D., Mallal, S., Knowles, S., Martin, A., Shear, N. and Phillips, E. (2004) Abacavir hypersensitivity syndrome: Results of clinical, immunological and genetic screening. In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 25 - 28 October 2004, Washington DC, U.S.A.

2003

Amin, J., Moore, A., Carr, A., French, M.A., Law, M., Emery, S., Cooper, D.A., Kotsiou, G., Norrito, L., Dwyer, D., Packham, D., Fordham, M., Garsia, R., Baker, D., Doong, N.C., Quan, D., Beveridge, A., Genn, W., Quin, J., Mulholland, J., Sowden, D., Rawlinsen, M., Rebic, D., Street, A., De Graaf, B., Roney, J., Bryant, M., McCormack, C., Hoy, J.N., Shaw, D.V., Ferguson, W., Waddell, R., Papanaoum, K., French, M.R., Scull, N., Todhunter, L., Mallal, S., James, R. and Foreman, E. (2003) Combined analysis of Two-Year Follow-up from two open-label randomized trials comparing efficacy of three nucleoside reverse transcriptase inhibitor backbones for previously untreated HIV-1 nfection: OzCombo 1 and 2. HIV Clinical Trials, 4 (4). pp. 252-261.

Cherry, C., Nolan, D., James, I., Mallal, S., McKinnon, E., French, M., Hammond, E., Gahan, M., McArthur, J. and Wesselingh, S. (2003) Longitudinal associations between antiretroviral treatments and quantification of tissue mitochondrial DNA from ambulatory subjects with HIV infection. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Christiansen, F.T., Gaudieri, S., De Santis, D., Moore, C.B., Witt, C.S., James, I.R. and Mallal, S. (2003) NK receptor genes are predictors of HIV progression. In: 29th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 28 October - 1 November 2003, Miami Beach, Florida.

Christiansen, F.T., Gaudieri, S., Moore, C.B., Martin, A., Nolan, D., James, I.R., McKinnon, E., DeSantis, D., Witt, C.S. and Mallal, S. (2003) The immune response to HIV: The interplay between virus and host genetic factors. In: British Society for Immunology Annual Congress, 2 - 5 December 2003, Harrogate, England.

Christiansen, F.T., Gaudieri, S., Santis, D.D., Moore, C.B., Witt, C.S., James, I.R. and Mallal, S.A. (2003) NK receptor genes are predictors of HIV progression. Human Immunology, 64 (10). S12.

Gaudieri, S., Moore, C., D'Aquilla, R., Dietrich, D., Lucas, M., Klenerman, P. and John, M. (2003) CTL hepatitis C virus escape mutants in HLA-diverse populations. In: 10th International Meeting on Hepatitis C Virus and Related Viruses, 2 - 6 December 2003, Kyoto, Japan.

Hammond, E., Nolan, D., James, I., McKinnon, E., White, A. and Mallal, S. (2003) Evidence of toxicity in Adipose tissue of HIV-infected patients correlates with NRTI-associated mtDNA depletion. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Hammond, E., Nolan, D., McKinnon, E., James, I. and Mallal, S. (2003) Subcutaneous fat tissue mitochondrial DNA depletion and adipose toxicity are strongly associated with nucleoside reverse transcriptase inhibitor (NRTI) therapy in HIV-infected patients. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Hammond, E.L., Sayer, D., Nolan, D., Walker, U.A., de Ronde, A., Montaner, J.S.G., Côté, H.C.F., Gahan, M.E., Cherry, C.L., Wesselingh, S.L., Reiss, P. and Mallal, S. (2003) Assessment of precision and concordance of quantitative mitochondrial DNA assays: A collaborative international quality assurance study. Journal of Clinical Virology, 27 (1). pp. 97-110.

Herrmann, S., Hyland, N., Coombs, A., Turner, K., Duncan, F., McKinnon, E., James, I., Martinez, O.P., French, M. and Mallal, S. (2003) Adherence to antiretroviral therapy in the WA HIV Cohort. In: 15th Annual Conference of the Australian Society for HIV Medicine, 22 - 25 October, Cairns, Australia.

James, I., Nolan, D., Hammond, E., McKinnon, E. and Mallal, S. (2003) Longitudinal effects on subcutaneous fatmass of initiating or switching stavudine and zidovudine-based antiretroviral therapy. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

James, I., Nolan, D., McKinnon, E., Hammond, E. and Mallal, S. (2003) Contribution of nucleoside analogue reverse transcriptase inhibitor therapy to lipodystrophy: Trends in subcutaneous fat wasting and association with mitochondrial DNA depletion. In: 7th International Workshop on HIV Observational Databases, 28-30 March 2003, Fiuggi, Italy.

John, M., McKinnon, E.J., James, I.R., Nolan, D., Herrmann, S.E., Moore, C.B., White, A.J. and Mallal, S.A. (2003) Randomised, controlled, 48-week study of switching stavudine and/or protease inhibitors to Combavir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33 (1). pp. 29-34.

Lincoln, D., Petoumenos, K., Dore, G.J., Finlayson, R., Clemons, J., Ellis, D., Baker, D., Kidd, J., McFarlane, R., Law, M., Smith, D., Huffam, D., Savage, J., Morgan, S., Knibbs, P., Rogers, G., Ree, H., Magon, H., Sowden, D., Walker, A., Orth, D., Lister, G.A., Chuah, J., James, R., Fankhauser, W., Dickson, B., Bradford, D., Wilson, C., Fairley, K., Roth, N., Eu, B., Strecker, S., Russell, D., Wood, H., Maijch, A., Hoy, J., Pierce, A., McCormack, C., Watson, K., Anderson, J.S., Moore, R., McGovern, G., McNair, R., Medland, N., Daye, J. and Mallal, S. (2003) HIV/HBV and HIV/HCV coinfection, and outcomes following highly active antiretroviral therapy. HIV Medicine, 4 (3). pp. 241-249.

Mallal, S. (2003) HIV Escape from antiretrovirals and CTL responses: Parallels and differences. In: 2nd IAS Conference on HIV Pathogenesis and Treatment, 13 - 16 July 2003, Paris, France.

Mallal, S. (2003) HIV adaptation to the genetic polymorphism of the host. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Mallal, S. (2003) Managing regimen difficulties: Meeting the challenges of safety and tolerability. Advanced Studies in Medicine, 3 (10B). S981-S986.

Mallal, S., Moore, C., Carvalho, F., Patterson, A., Liu, C., Goodridge, D., Sayer, D., James, I. and John, M. (2003) HIV adaptation to HLA-restricted immune responses - implications for vaccine design and evaluation. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Martin, A., Gaudieri, S., Witt, C., Nolan, D., Christiansen, F.T. and Mallal, S. (2003) Mapping of genetic susceptibility to abacavir hypersensitivity. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Martin, A., Nolan, D., Gaudieri, S., Almeida, C., Carvalho, F., Witt, C., Sayer, D., Nolan, R., Herrmann, S., Christiansen, F. and Mallal, S. (2003) Updated experience of abacavir hypersensitivity genetic testing within the major histocompatibility complex (MHC): addressing diagnostic precision and predictive value. In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 8 - 11 July, Paris, France.

Martin, A.M., Hammond, E., Nolan, D., Pace, C., den Boer, M., Taylor, L., Moore, H., Martinez, O.P., Christiansen, F.T. and Mallal, S. (2003) Accumulation of mitochondrial DNA mutations in Human Immunodeficiency Virus–infected patients treated with Nucleoside-analogue Reverse-transcriptase inhibitors. American Journal of Human Genetics, 72 (3). pp. 549-560.

Martin, A.M., Hammond, E., Nolan, D., Pace, C., den Boer, M., Taylor, L., Moore, H., Martinez, O.P., Christiansen, F.T. and Mallal, S. (2003) Accumulation of mitochondrial DNA mutations in human immunodeficiency Virus–infected patients treated with Nucleoside-analogue Reverse-transcriptase inhibitors. The American Journal of Human Genetics, 72 (3). p. 1358.

McKinnon, E., Fusco, J., John, M., Fusco, G., James, I. and Mallal, S. (2003) Virological response to first HAART - a CHORUS/WAHIV collaborative study. In: 7th International Workshop on HIV Observational Databases, 28-30 March 2003, Fiuggi, Italy.

McKinnon, E.J., James, I.R., John, M. and Mallal, S.A. (2003) Viral load detectability profiles for HIV infection. Statistics in Medicine, 22 (3). pp. 385-396.

McKinnon, E.J., James, I.R. and Mallal, S. (2003) Response to HAART: Host genetic associations. In: Annual North American Observational Database Meeting, 13 November 2003, Washington DC, U.S.A.

Miller, J., Carr, A., Emery, S., Law, M., Mallal, S., Baker, D., Smith, D., Kaldor, J. and Cooper, D.A. (2003) HIV lipodystrophy: Prevalence, severity and correlates of risk in Australia. HIV Medicine, 4 (3). pp. 293-301.

Nolan, D. (2003) Metabolic complications associated with HIV protease inhibitor therapy. Drugs, 63 (23). pp. 2555-2574.

Nolan, D. and Christiansen, F. (2003) 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV. Expert Opinion on Drug Safety, 2 (1). pp. 95-101.

Nolan, D., Gaudieri, S. and Mallal, S. (2003) Pharmacogenetics: A practical role in predicting antiretroviral drug toxicity? Journal of HIV therapy, 8 (2). pp. 36-41.

Nolan, D., Hammond, E., James, I., McKinnon, E. and Mallal, S. (2003) Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antiviral Therapy, 8 (6). pp. 617-626.

Nolan, D., Hammond, E., Martin, A., Taylor, L., Herrmann, S., McKinnon, E., Metcalf, C., Latham, B. and Mallal, S. (2003) Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS, 17 (9). pp. 1329-1338.

Nolan, D. and Mallal, S. (2003) Thymidine analogue-sparing highly active antiretroviral therapy (HAART). Journal of HIV therapy, 8 (1). pp. 1-5.

Nolan, D., Moore, C., Castley, A., Sayer, D., Marmotte, C., John, M., James, I. and Mallal, S. (2003) Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS, 17 (1). pp. 121-123.

Nolan, D., Watts, G.F., Herrmann, S.E., French, M.A., John, M. and Mallal, S. (2003) Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk? QJM, 96 (11). pp. 825-832.

Nolan, R., Martin, A.M., Nolan, D., Gaudieri, S., Almeida, C., Carvalho, F., Witt, C., Sayer, D., Herrmann, S., Christiansen, F.T. and Mallal, S. (2003) Abacavir Hypersensitivity Syndrome: Clarifying genetic associations by including the presence of an abacavir specific immune response in diagnostic criteria. In: 15th Annual Conference of the Australian Society for HIV Medicine, 22 - 25 October, Cairns, Australia.

Pace, C., Martin, A., Mamotte, C., Hammond, E., Nolan, D. and Mallal, S. (2003) Effects of HAART on expression (mRNA) of PPAR-gamma, UCP2, UCP1, mitochondrial DNA depletion and proliferation. In: 10th Conference on Retroviruses and Opportunistic Infections, 10 - 14 February 2003, Boston, U.S.A.

Pace, C.S., Martin, A.M., Hammond, E.L., Mamotte, C.D.S., Nolan, D.A. and Mallal, S.A. (2003) Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antiviral Therapy, 8 (4). pp. 323-331.

Telenti, A., Beckmann, J.S. and Mallal, S. (2003) HLA and HIV: Modeling adaptation to moving targets. The Pharmacogenomics Journal, 3 (5). pp. 254-256.

2002

Christiansen, F.T., Gaudieri, S., De Santis, D., Witt, C.S., James, I.R. and Mallal, S. (2002) NK receptor genes are predictors of HIV progression. In: 28th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 19 - 23 October 2002, Nashville, TN

Christiansen, F.T., John, M., James, I., Witt, C. and Mallal, S. (2002) Immune escape mutations in HIV-1 sequence: the influence of HLA class I and II alleles in a host population on viral evolution. In: 28th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, 19 - 23 October 2002, Nashville, TN

Christiansen, F.T., John, M., James, I.R., Witt, C.S. and Mallal, S.A. (2002) Immune escape mutations in HIV-1 sequence: the influence of HLA class I and II alleles in a host population on viral evolution. Human Immunology, 63 (10). S35.

Doherty, D.A., James, I.R. and Newnham, J.P. (2002) Estimation of the Doppler ultrasound maximal umbilical waveform envelope: I. Estimation method. Ultrasound in Medicine & Biology, 28 (10). pp. 1251-1259.

Hammond, E., Nolan, D., Martin, A., Sayer, D. and Mallal, S. (2002) A real-time PCR-based method for detecting mitochondrial DNA depletion: Assessment of assay precision. In: Keystone Symposia on Mitochondria and Pathogenesis, 6 - 12 April 2002, Copper Mountain, Colorado

Hammond, E., Nolan, D., McKinnon, E. and Mallal, S. (2002) No evidence of mitochondrial DNA depletion in peripheral white blood cells after three to 12 months of HAART. In: XIV International AIDS conference, 7 - 12 July 2002, Barcelona, Spain

James, I., McKinnon, E. and Mallal, S. (2002) Comparison of rates of progression in HIV observational cohorts. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

John, M., James, I., McKinnon, E., Nolan, D., Herrmann, S., Cain, A., Martinez, O.P., White, A. and Mallal, S. (2002) A randomised, controlled, Open-label study of revision of antiretroviral regimens containing stavudine (d4T) and/or a Protease Inhibitor (PI) to Zidovudine (ZDV)/Lamivudine (3TC)/Abacavir (ABC) to prevent or reverse lipoatrophy: 48-week data. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

John, M. and Mallal, S. (2002) Hyperlactatemia syndromes in people with HIV infection. Current Opinion in Infectious Diseases, 15 (1). pp. 23-29.

John, M., Moore, C., James, I. and Mallal, S. (2002) Immune escape mutations in HIV-1 at a population level. In: GSK Observational HIV Cohorts Meeting, 6 - 7 November 2002, Boston, U.S.A

John, M., Moore, C.B., James, I.R., Christiansen, F.T., Witt, C.S. and Mallal, S.A. (2002) Immune escape mutations in HIV-1 sequence: The influence of HLA class I and II alleles in a host population on viral evolution. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A

Mallal, S. (2002) Lipodystrophy - Insights from epidemiology and the laboratory. In: Australasian Society for HIV Medicine Conference 2002, 26 October 2002, Sydney, Australia.

Mallal, S. (2002) Long-term complications of antiretroviral therapy. In: HIV Treatment 2002: Management in the 3rd Decade, 14 - 17 November 2002, Phoenix, Arizona.

Mallal, S. (2002) Managing regimen difficulties: Meeting the challenge of safety and tolerability. In: CME Symposium: 2nd IAS Conference on HIV Pathogenesis and Treatment, 13 - 16 July 2003, Paris, France.

Mallal, S. (2002) Mitochondrial toxicity. In: 12th Clinical Care Options for HIV Symposium, 27 April 2002, Key Biscayne, Florida.

Mallal, S. (2002) Understanding and managing the metabolic complications of antiretroviral therapy. In: Cedar Sinai Hospital Grand Rounds, 30 April 2002, Los Angeles, U.S.A.

Mallal, S. (2002) Update on risk factors and management of lipodystrophy. In: 3rd European Workshop on Lipodystrophy, 25 April 2002, Marbella, Spain.

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F. (2002) The presence of HLA-B*5701, -DRB1*0701, and -DQ3 Is highly predictive of hypersensitivity to the HIV reverse transcriptase inhibitor abacavir. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A.M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I. and Christiansen, F.T. (2002) Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. The Lancet, 359 (9308). pp. 727-732.

Mallal, S., Witt, C., Martin, A.M., Masel, G., Moore, C., Sayer, D., Castley, A., Mamotte, C., Nolan, D., James, I. and Christiansen, F.T. (2002) The presence of HLA-B*5701, -DRB1*0701 and -DQ3 is highly predictive of hypersensitivity to the HIV reverse transcriptase inihibitor abacavir. In: XIII International Congress of Histocompatibility and Immunogenetics, 18 - 22 May 2002, Seattle, U.S.A.

McKinnon, E., Fusco, J., Fusco, G., John, M., James, I. and Mallal, S. (2002) Virologic response to HAART in the CHORUS cohort. In: GSK Observational HIV Cohorts Meeting, 6 - 7 November 2002, Boston, U.S.A.

McKinnon, E., James, I. and Mallal, S. (2002) Progessive matching in HIV observational studies. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

McKinnon, E., John, M., James, I. and Mallal, S. (2002) Effect of baseline CD4 on virological response to first HAART. In: 6th International Workshop on HIV Observational Databases, 21 - 22 March 2002, Sintra, Portugal

Moore, C., John, M., James, I. and Mallal, S. (2002) The influence of host HLA on antiretroviral drug resistance mutation in HIV-1. In: 9th Conference on Retroviruses and Opportunistic Infections, 24 - 28 February 2002, Seattle, U.S.A.

Moore, C.B., John, M., James, I.R., Christiansen, F.T., Witt, C.S. and Mallal, S. (2002) Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level. Science, 296 (5572). pp. 1439-1443.

Nolan, D., James, I., McKinnon, E. and Mallal, S. (2002) Stavudine, zidovudine and protease inhibitor therapy effects on subcutaneous leg fat wasting in HIV-infected males. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Nolan, D., Moore, C., Castley, A., Sayer, D., Mamotte, C., John, M., James, I. and Mallal, S. (2002) Tumour necrosis factor alpha gene - 238G/A promoter polymorphism associated with more rapid onset of lipodystrophy. In: 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 22 - 25 September 2002, San Diego, CA

Petoumenos, K., Austin, D., Baker, D., Block, M., Brown, K., Carr, A., Cooper, D., Couldwell, D., Ellis, D., Finlayson, R., Gorton, C., Gowers, A., Keeffe, N., Kidd, J., Law, M., Liang, M.T., McFarlane, R., Mutimer, K., Miller, J., O'Connor, C., Quan, D., Rooney, P., Taylor, S., Smith, D., Wheatley, D., Knibbs, P., Huffam, S., Morgan, S., Savage, J., Bradford, D., Chuah, J., Dickson, B., Fankhauser, W., Lister, G., Magon, H., Orth, D., Rawlinson, M., Ree, H., Sowden, D., Walker, A., Wilson, C., Anderson, J., Bal, J., Daye, J., Eu, B., Fairely, C.K., Hoy, J., McCormack, C., McGovern, G., McNair, R., Medland, N., Mijch, A., Moore, R., Pierce, A., Roth, N., Russell, D., Strecker, S., Watson, K., Wood, H., Cain, A., French, M., Mallal, S., Maxwell, D., Moore, C. and Skett, J. (2002) Rates of combination antiretroviral treatment change in Australia, 1997-2000. HIV Medicine, 3 (1). pp. 28-36.

2001

Carr, A., Hudson, J., Chuah, J., Mallal, S., Law, M., Hoy, J., Doong, N., French, M., Smith, D. and Cooper, D.A. (2001) HIV protease inhibitor substitution in patients with lipodystrophy: A randomized, controlled, open-label, multicentre study. AIDS, 15 (14). pp. 1811-1822.

Hammond, E.L., Martin, A., Taylor, L., John, M., Nolan, D.A. and Mallal, S. (2001) Mitochondrial DNA depletion, assessed by real-time PCR-based quantitative assay in subcutaneous fat of HIV infected patients: Evidence for a role in the aetiology of fat wasting. In: 4th International Conference on Nutrition and HIV infection/2nd European Workshop on Lipodystrophy, 19 - 21 April 2001, Cannes, France

Ioannidis, J.P.A., Rosenberg, P.S., Goedert, J.J., Ashton, L.J., Benfield, T.L., Buchbinder, S.P., Coutinho, R.A., Eugen-Olsen, J., Gallart, T., Katzenstein, T.L., Kostrikis, L.G., Kuipers, H., Louie, L.G., Mallal, S.A., Margolick, J.B., Martinez, O.P., Meyer, L., Michael, N.L., Operskalski, E., Pantaleo, G., Rizzardi, G.P., Schuitemaker, H., Sheppard, H.W., Stewart, G.J., Theodorou, I.D., Ullum, H., Vicenzi, E., Vlahov, D., Wilkinson, D., Workman, C., Zagury, J-F and O'Brien, T.R. (2001) Effects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data. Annals of Internal Medicine, 135 (9). pp. 782-795.

James, I., Moore, C., John, M., Nolan, D., McKinnon, E. and Mallal, S. (2001) Effect of HAART on subcutaneous fat in HIV-infected males: A longitudinal study. In: 5th International Workshop on HIV Observational Databases, 26 - 27 April 2001, Monte Carlo

John, M., Moore, C., James, I. and Mallal, S. (2001) Characteristic Non-synonymous mutation in HIV reverse transcriptase sequence encoding an HLA-B7-restricted CTL epitope is associated with increased viral load. In: 8th Conference on Retroviruses and Opportunistic Infections , 4 - 8 February 2001, Chicago, IL

John, M., Moore, C., James, I. and Mallal, S. (2001) Selection of immune escape mutation in HIV-1 is evident at a population level. In: 13th Annual Conference of the Australian Society for HIV Medicine, 4 - 7 October 2001, Melbourne, VIC

John, M., Moore, C.B., James, I.R., Nolan, D., Upton, R.P., McKinnon, E.J. and Mallal, S.A. (2001) Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS, 15 (6). pp. 717-723.

John, M., Nolan, D. and Mallal, S. (2001) Antiretroviral therapy and the lipodystrophy syndrome. Antiviral Therapy, 6 (1). pp. 9-20.

Mallal, S., Hammond, E., Martin, A. and Nolan, D.A. (2001) Mitochondrial DNA depletion in adipocytes associated with NRTI treatment in HIV infected individuals. In: 8th European Conference of Clinical Aspects and Treatment of HIV-Infection, 27 - 31 October 2001, Athens, Greece

Murray, R., Mallal, S., Heath, C. and French, M. (2001) Cerebral mycobacterium avium infection in an HIV-Infected patient following immune reconstitution and cessation of therapy for disseminated mycobacterium avium complex infection. European Journal of Clinical Microbiology and Infectious Diseases, 20 (3). pp. 199-201.

Nolan, D. (2001) Review of the Third International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Athens, 2001. Nutrition and Metabolic Disorders in HIV Infection, 2002 (1). pp. 1-14.

Nolan, D., Hammond, E., Martin, A., Metcalf, C., Latham, B., John, M. and Mallal, S. (2001) NRTI therapy is associated with mitochondrial DNA depletion, increased mitochondrial biogenesis and subcutaneous fat wasting in HIV infected patients. In: 1st IAS Conference on HIV Pathogenesis and Treatment, 8 - 11 July 2001, Buenos Aires, Argentina

Nolan, D., John, M. and Mallal, S. (2001) Antiretoviral therapy and the lipodystrophy syndrome, part 2: Concepts in aetiopathogenesis. Antiviral Therapy, 6 (3). pp. 145-160.

Nolan, D. and Mallal, S. (2001) Effects of sex and race on lipodstrophy pathogenesis. Journal of HIV therapy, 6 (1). pp. 32-36.

Nolan, D. and Mallal, S. (2001) Getting to the HAART of insulin resistance. AIDS, 15 (15). pp. 2037-2041.

Nolan, D., Upton, R., McKinnon, E., John, M., James, I., Adler, B., Roff, G., Vasikaran, S. and Mallal, S. (2001) Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir. AIDS, 15 (10). pp. 1275-1280.

Rooney, P., Taylor, S., Couldwell, D., Austin, D., Block, M., Quan, D., Gowers, A., O'Conner, C., Gorton, C., Allen, D., Mulhall, B., Mutimer, K., Smith, D., Keeffe, N., Cooper, D., Carr, A., Miller, J., Finlayson, R., Wheatley, D., Ellis, D., Baker, D., Kidd, J., McFarlane, R., Liang, M.T., Brown, K., Petoumenos, K., Law, M., Huffam, S., Savage, J., Morgan, S., Knibbs, P., Sowden, D., Rawlinson, M., Walker, A., Orth, D., Lister, G., Chuah, J., Fankhauser, W., Dickson, B., Bradford, D., Wilson, C., Ree, H., Magon, H., Fairley, C.K., Roth, N., Eu, B., Strecker, S., Russel, D., Wood, H., Mijch, A., Hoy, J., Pierce, A., McCormack, C., Watson, K., Anderson, J., Moore, R., Russell, D., McGovern, G., McNair, R., Bal, J., Medland, N., Daye, J., Mallal, S., French, M., Skett, J., Moore, C., Maxwell, D. and Cain, A. (2001) Time trends in antiretroviral treatment use in Australia, 1997-2000. Venereology, 14 (4). pp. 162-168.

2000

Gizzarelli, L., Hammond, E., Martin, A., Nolan, D. and Mallal, S. (2000) Level of heteroplasmy DNA detection in mtDNA using SSCP and DNA sequencing. In: 12th Annual Conference of the Australian Society for HIV Medicine, 12 - 14 October 2000, Melbourne, Australia

Law, M.G. and Mallal, S. (2000) Rates of change of combination antiretroviral treatments in Australia, 1997-2000. In: 5th International Congress on Drug Therapy in HIV Infection, 22 - 26 October 2000, Glasgow, U.K

Mallal, S. (2000) What are the relative contributions of NRTIs and protease inhibitors to lipodystrophy? In: 4th International Conference on Nutrition and HIV infection/2nd European Workshop on Lipodystrophy, 19 - 21 April 2001, Cannes, France.

Moore, C., John, M., James, I. and Mallal, S. (2000) Characteristic mutations in HIV-1 reverse transcriptase sequence encoding HLA class I restricted CTL epitopes: Evidence of HIV-1 CTL escape at a population level. In: 24th Annual Australasian and South East Asian Tissue Typing Association Conference, 30 November - 3 December 2000, Perth, Western Australia

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada.

Petoumenos, K. and Mallal, S. (2000) Use of combination antiretroviral treatments in Australia, 1997-2000. In: 12th Annual Conference of the Australian Society for HIV Medicine, 12 - 14 October 2000, Melbourne, Australia

White, A.J., John, M., Moore, C., James, I.R., Nolan, D. and Mallal, S.A. (2000) Raised lactate levels are common and may be predictive of subcutaneous fat wasting. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada

1999

Herbison, C.E., Sayer, D.C., Bellgard, M., Allcock, R.J, Christiansen, F.T. and Price, P. (1999) Structure and polymorphism of two stress-activated protein kinase genes centromeric of the MHC: SAPK2a and SAPK4. DNA sequence : the journal of DNA sequencing and mapping, 10 (4-5). pp. 229-243.

This list was generated on Tue Jul 29 09:47:24 2014 IST.