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Giardia duodenalis mouse model for the development of novel antigiardial agents

Abraham, R.J., O'Dea, M., Rusdi, B., Page, S.W., O'Handley, R. and Abraham, S. (2018) Giardia duodenalis mouse model for the development of novel antigiardial agents. Journal of Microbiological Methods, 145 . pp. 7-9.

Link to Published Version: https://doi.org/10.1016/j.mimet.2017.11.025
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Abstract

This study describes a neonatal mouse model of Giardia infection for development of novel antigiardials. Mice were infected with the axenically cultured Assemblage A BAH2c2 strain, with 105 trophozoites per animal recovered. This model proved to be robust and consistent for use in preliminary drug efficacy trials and drug development.

Publication Type: Journal Article
Murdoch Affiliation: School of Veterinary and Life Sciences
Publisher: Elsevier BV
Copyright: © 2017 Published by Elsevier B.V
URI: http://researchrepository.murdoch.edu.au/id/eprint/39957
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