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Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge)

Huxtable, C.R., Dorling, P.R. and Colegate, S.M. (1993) Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge). Australian Veterinary Journal, 70 (5). pp. 169-171.

Link to Published Version: http://dx.doi.org/10.1111/j.1751-0813.1993.tb06120...
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Abstract

An Isoprenyl guanldine, galegine, was isolated from the Western Australian sedge Schoenus asperocarpus (Cyperaceae). Synthetic galegine was shown to reproduce the clinical and pathological features of poisoning by this plant. Preliminary results suggest that the massive thoracic effusion observed in sedge poisoning is the result of a direct effect on pulmonary vascular permeability.

Publication Type: Journal Article
Murdoch Affiliation: School of Veterinary Studies
Publisher: Wiley-Blackwell
URI: http://researchrepository.murdoch.edu.au/id/eprint/35787
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