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Synthesis of 2-acetyl-5,8-dimethoxytetralin - an important anthracyclinone intermediate

Giles, R.G.F. and Green, I.R. (1990) Synthesis of 2-acetyl-5,8-dimethoxytetralin - an important anthracyclinone intermediate. South African Journal of Chemistry, 43 (3-4). pp. 87-90.

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Abstract

The important anthracyclinone intermediate, 2-acetyl-5,8-dimethoxytetralin, has been synthesized in five
steps in an overall yield of 51 % starting from 5,8-dihydroxy-1 ,4-dihydronaphthalene. Since all the steps are
straightforward the method lends itself to muhigram synthesis.

Publication Type: Journal Article
Publisher: South African Bureau for Scientific Publications
Copyright: © 1990 South African Chemical Institute (SACI)
URI: http://researchrepository.murdoch.edu.au/id/eprint/35749
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