Catalog Home Page

In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin

van de Sande, W.W.J., Fahal, A.H., Riley, T.V., Verbrugh, H. and van Belkum, A. (2007) In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin. Journal of Antimicrobial Chemotherapy, 59 (3). pp. 553-555.

Link to Published Version: http://dx.doi.org/10.1093/jac/dkl526
*Subscription may be required

Abstract

Objectives: Eumycetoma caused by Madurella mycetomatis is treated with surgery and high doses of itraconazole and ketoconazole. These agents are toxic, and new therapies are required.

Methods: MICs were determined for artemisinin and tea tree oil, two natural herbal compounds.

Results: Artemisinin was not active against M. mycetomatis, but tea tree oil did inhibit its growth. Since tea tree oil's prime component easily penetrates the skin, tea tree oil could be a useful agent in the treatment of eumycetoma.

Conclusions: Tea tree oil is active in vitro against M. mycetomatis. © The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

Publication Type: Journal Article
Publisher: Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy
Copyright: © 2007 The Author
URI: http://researchrepository.murdoch.edu.au/id/eprint/35377
Item Control Page Item Control Page