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Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in tolerance to tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-Cineole, and α-Terpineol ∇

Papadopoulos, C.J., Carson, C.F., Chang, B.J. and Riley, T.V. (2008) Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in tolerance to tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-Cineole, and α-Terpineol ∇. Applied and Environmental Microbiology, 74 (6). pp. 1932-1935.

Link to Published Version: http://dx.doi.org/10.1128/AEM.02334-07
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Abstract

Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and α-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.

Publication Type: Journal Article
Publisher: American Society for Microbiology
Copyright: © 2008 American Society for Microbiology
URI: http://researchrepository.murdoch.edu.au/id/eprint/35367
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