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A novel barley β-glucan extract (Glucagel TM) in combination with flax or coconut oil influences cholesterol and triglyceride levels in growing rats

Maqueda de Guevara, M.L., Morel, P.C.H., Coles, G.D and Pluske, J. (2000) A novel barley β-glucan extract (Glucagel TM) in combination with flax or coconut oil influences cholesterol and triglyceride levels in growing rats. In: Proceedings of the Nutrition Society of Australia, 24, 3 - 6 December, Fremantle, Western Australia pp. 209-212.

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Abstract

A 2 x 2 factorial arrangement of treatments was used to test the hypothesis that inclusion of a novel P-glucan extract (GlucagelTM) in cholesterol-free synthetic diets containing coconut oil or flax oil would lower circulating total cholesterol (TC) and triglyceride (TG) levels in growing rats. Inclusion of Glucagel™ (100 g/kg) tended to decrease TC levels (P=0.07), however TC level was not influenced by oil type (P>0.05). A significant interaction (P<0.05) occurred for TG levels, with the addition of p-glucan to diets containing coconut oil and flax oil decreasing TG levels by 40% (P<0.01) and 13% (P>0.05), respectively. Faecal digestibility of fat was reduced by 7% (P=0.08) in rats fed coconut oil plus P-glucan. These data suggest that reduced TG levels caused by addition of p-glucan may be mediated in part by reduced fat digestion in the small intestine, an effect most likely caused by the unique gel-forming properties of Glucagel™

Publication Type: Conference Paper
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Publisher: Nutrition Society of Australia
URI: http://researchrepository.murdoch.edu.au/id/eprint/28527
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