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Neonatal oxytocin administration and weaning onto a gruel based diet reduce weight loss at weaning and enhance gastric leptin expression

Ferrari, J.M., Pluske, J.R., Miller, D.W., Clarke, I.J. and Dunshea, F.R. (2007) Neonatal oxytocin administration and weaning onto a gruel based diet reduce weight loss at weaning and enhance gastric leptin expression. In: Manipulating Pig Production XI. Proceedings of the 11th Australasian Pig Science Association (APSA) Biennial Conference, 25 - 28 October, Brisbane, Australia p. 184.

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Abstract

Administering oxytocin to neonatal rats has positive long-term effects on growth and development (Uvnas-Moberg and Petersson, 2005). These effects include a reduction in the stress response to weaning, increased post-weaning feed intake and alterations in the expression of gastrointestinal (GI) hormones regulating feed intake (Uvnas-Moberg et al., 1998; Sohlstrom et al., 1999). Two GI hormones of importance in regulating feed intake are ghrelin and leptin, which have antagonistic actions. Ghrelin expression is increased in response to fasting and leptin expression increases rapidly in response to feed intake. Since weaning the piglet is associated with stress and growth restriction, this study examined whether oxytocin given to young pigs could reduce the extent of the post-weaning growth check, along with any associated changes in ghrelin and leptin expression.

Publication Type: Conference Paper
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Publisher: Australasian Pig Science Association
Copyright: © 2007 Australasian Pig Science Association (Inc)
URI: http://researchrepository.murdoch.edu.au/id/eprint/28031
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