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Enzymatic incorporation of LNA nucleotides

Wengel, J., Vester, B. and Veedu, R.N. (2009) Enzymatic incorporation of LNA nucleotides. Patent No: WO/2009/039862 .

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Abstract

The present invention relates to oligonucleotides comprising LNA units and enzymatic methods of synthesizing such oligonucleotides. Oligonucleotide comprising LNA units have various characteristics, e.g. improved biostability and increased > affinity for complementary oligonucleotides. The methods may be part of detection reactions, polymerase chain reaction, RNA transcription or in vitro evolution processes such as SELEX.

Publication Type: Others
Publisher: RIBOTASK APS
URI: http://researchrepository.murdoch.edu.au/id/eprint/27266
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