Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development
de la Fuente, J., Lew, A.E., Lutz, H., Meli, M.L., Hofmann-Lehmann, R., Shkap, V., Molad, T., Mangold, A.J., Almazán, C., Naranjo, V., Gortázar, C., Torina, A., Caracappa, S., García-Pérez, A.L., Barral, M., Oporto, B., Ceci, L., Carelli, G., Blouin, E.F. and Kocan, K.M. (2005) Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development. Animal Health Research Reviews, 6 (1). pp. 75-89.
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The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes several pathogens of veterinary and human medical importance. An understanding of the diversity of Anaplasma major surface proteins (MSPs), including those MSPs that modulate infection, development of persistent infections, and transmission of pathogens by ticks, is derived in part, by characterization and phylogenetic analyses of geographic strains. Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis.
|Publication Type:||Journal Article|
|Publisher:||Cambridge University Press|
|Copyright:||© 2005 CAB International|
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