Influence of NRTI choice and efavirenz versus lopinavir treatment options on lipoatrophy-associated adipose tissue toxicity: A longitudinal study
Hammond, E., McKinnon, E., Pace, C., Mallal, S. and Nolan, D. (2008) Influence of NRTI choice and efavirenz versus lopinavir treatment options on lipoatrophy-associated adipose tissue toxicity: A longitudinal study. In: 15th Conference on Retroviruses and Opportunistic Infections (CROI), 3 - 6 February 2008, Boston, U.S.A.
Clinical trials and cohort data have demonstrated associations between thymidine NRTI (particularly stavudine) use and lipoatrophy, while more recent data from ACTG 5142 study suggest an additional effect of efavirenz versus lopinavir therapy [Haubrich R et al. 14th CROI, 2007, #38]. This study investigates the effects of HIV treatment choice in longitudinal adipose tissue specimens.
|Publication Type:||Conference Item|
|Murdoch Affiliation:||Centre for Clinical Immunology and Biomedical Statistics|
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