Studies on pathogenesis, tissue infection and congenital transmission in cows experimentally infected with Sarcocystis cruzi by various routes
Savini, G., Dunsmore, J.D. and Robertson, I.D. (1996) Studies on pathogenesis, tissue infection and congenital transmission in cows experimentally infected with Sarcocystis cruzi by various routes. Veterinary Parasitology, 64 (4). pp. 319-327.
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A group of nine cows, naturally infected with Sarcocystis, were challenged with Sarcocystis cruzi: three intrarumenally with sporocysts, two intrarumenally with water (controls), two intravenously with merozoites grown in vitro and two intravenously with saline solution (controls). The animals intrarumenally challenged with sporocysts developed acute sarcocystiosis and produced stillborn calves, whereas those intravenously challenged with merozoites suffered from subclinical sarcocystiosis with premature births. No parasites were found in calves from cows challenged with sporocysts; however, a meront of Sarcocystis was found in calves from cows the cerebrospinal fluid of a calf from a cow intravenously inoculated with merozoites of S. cruzi. This is the first time that merozoites of S. cruzi grown in vitro have been demonstrated to retain the ability to infect their natural intermediate host and complete their life cycle.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Veterinary Studies|
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