Constituents of Conospermum brachyphyllum. Improved Methods for the Isolation and Synthesis of (+)-Conocurvone and the Structure of (+)-Brachyphyllone
Armstrong, J.A., Baker, R.W., Best, W.M., Byrne, L.T., Cannon, J.R., Colegate, S.M., Gray, A.R., Marchant, N.G., Rothnie, N., Sargent, M.V., Sims, C.G., Spadek, Z.E. and Trengove, R.D. (1999) Constituents of Conospermum brachyphyllum. Improved Methods for the Isolation and Synthesis of (+)-Conocurvone and the Structure of (+)-Brachyphyllone. Australian Journal of Chemistry, 52 (1). pp. 57-62.
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Improved methods have been devised for the isolation of (+)-conocurvone (1) from the roots of Conospermum brachyphyllum Lindl. and for its synthesis. The isolation of (R)-(+)-9-hydroxy-3-(4′-hydroxy-4′-methylpentan-1′-yl)-3,8-dimethyl-3H-naphtho[2,1-b]pyran-7,10-dione [(+)-brachyphyllone] (2), a minor constituent of this species, its structural elucidation and partial synthesis are also described. 8-C-Methylteretifolione-B (9) and 8-C-methyl-9-O-methylteretifolione-B (10), as well as the previously isolated (+)-teretifolione-B (8), also occur in this plant.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Veterinary and Biomedical Sciences|
|Publisher:||Commonwealth Scientific and Industrial Research Organization Publishing|
|Copyright:||© CSIRO 1999|
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