Asymmetric syntheses of Isochroman-4,7-diols through intramolecular cyclization of tethered lactaldehydes
Giles, R.G.F., Green, I.R., Gruchlik, Y. and Oosthuizen, F.J. (2000) Asymmetric syntheses of Isochroman-4,7-diols through intramolecular cyclization of tethered lactaldehydes. Australian Journal of Chemistry, 53 (4). pp. 341-347.
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Ready cyclization through silica gel chromatography of the asymmetric phenolic lactaldehyde (14) afforded the diastereomeric pair of isochroman-4,7-diols (21) and (23) in good yield, while (17), the benzylic epimer of (14), similarly yielded the isochroman-4,7-diol (25) as a single diastereomer.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Chemical and Mathematical Science|
|Publisher:||Commonwealth Scientific and Industrial Research Organization Publishing|
|Copyright:||© 2000 CSIRO|
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