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Asymmetric syntheses of Isochroman-4,7-diols through intramolecular cyclization of tethered lactaldehydes

Giles, R.G.F., Green, I.R., Gruchlik, Y. and Oosthuizen, F.J. (2000) Asymmetric syntheses of Isochroman-4,7-diols through intramolecular cyclization of tethered lactaldehydes. Australian Journal of Chemistry, 53 (4). pp. 341-347.

Link to Published Version: http://dx.doi.org/10.1071/CH00020
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Abstract

Ready cyclization through silica gel chromatography of the asymmetric phenolic lactaldehyde (14) afforded the diastereomeric pair of isochroman-4,7-diols (21) and (23) in good yield, while (17), the benzylic epimer of (14), similarly yielded the isochroman-4,7-diol (25) as a single diastereomer.

Publication Type: Journal Article
Murdoch Affiliation: School of Chemical and Mathematical Science
Publisher: Commonwealth Scientific and Industrial Research Organization Publishing
Copyright: © 2000 CSIRO
URI: http://researchrepository.murdoch.edu.au/id/eprint/17426
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