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Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD

Nolan, D., Upton, R., James, I., McKinnon, E., John, M. and Mallal, S. (2000) Longitudinal analysis of Bone Mineral Density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. In: 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 13 - 15 September 2000, Toronto, Canada.

Abstract

- A cross sectional analysis, a relatively high rate of osteopenia and osteoporosis (49%), which was higher in patients on PI-containing regimens.

- Rate of bone loss and observed a paradoxical increase in the BMD in patients treated with indinavir vs. patients treated with nelfinavir and related these changes to the changes in subcutaneous fat, regardless of therapy.

Publication Type: Conference Item
Murdoch Affiliation: Centre for Clinical Immunology and Biomedical Statistics
URI: http://researchrepository.murdoch.edu.au/id/eprint/15401
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