Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection
Chaubey, S.K., Sinha, A.K., Phillips, E., Russell, D.B. and Falhammar, H. (2009) Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection. Sexual Health, 6 (3). pp. 254-257.
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A 42-year-old Thai man was administered the combination drugs liponavir/ritonavir and abacavir/lamivudine. On day 3 he was admitted and his electrocardiogram demonstrated sinus arrest with junctional escape rhythm with a rate of 42 min-1. Three days after stopping the medication he reverted to normal sinus rhythm. A 55-year-old Caucasian man was admitted to hospital with triple vessel disease. He had a permanent pace maker inserted 4 years previously for Mobitz type II AV block detected on stress electrocardiogram, which developed 1 month after initiation of lopinavir/ritonavir. These two cases highlight the importance of considering lopinavir/ritonavir induced arrhythmias when dealing with HIV-positive individuals.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||Institute for Immunology and Infectious Diseases|
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