Identification and isolation of rodent lung dendritic cells
Stumbles, P.A., Thomas, J. and Holt, P.G. (2001) Identification and isolation of rodent lung dendritic cells. Methods in Molecular Medicine, 64 . pp. 73-83.
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Dendritic cells (DC) are a trace cell population found in most tissues that display potent antigen acquisition and presentation capabilities and are unique among antigen-presenting-cell types in their ability to activate unprimed T cells (1). DC are particularly prominent at the mucosal surfaces of the lung and gastrointestinal tract, where they are thought to play a critical role in the regulation of immune responses to environmental antigens (2-4).
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