Sequence differences in the diagnostic target region of the oocyst wall protein gene of Cryptosporidium parasites
Xiao, L., Limor, J., Morgan, U.M., Sulaiman, I., Thompson, R.C.A. and Lal, A.A. (2000) Sequence differences in the diagnostic target region of the oocyst wall protein gene of Cryptosporidium parasites. Applied and Environmental Microbiology, 66 (12). pp. 5499-5502.
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Nucleotide sequences of the Cryptosporidium oocyst wall protein (COWP) gene were obtained from Various Cryptosporidium spp. (C. wrairi, C. felis, C. meleagridis, C. baileyi, C. andersoni, C. muris, and C. serpentis) and C. parvum genotypes (human, bovine, monkey, marsupial, ferret, mouse, pig, and dog). Significant diversity was observed among species and genotypes in the primer and target regions of a popular diagnostic PCR. These results provide useful information for COWP-based molecular differentiation of Cryptosporidium spp. and genotypes.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||Western Australian State Agricultural Biotechnology Centre|
School of Veterinary and Biomedical Sciences
|Publisher:||American Society for Microbiology|
|Copyright:||© 2000 American Society for Microbiology|
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