Assessment of an approximate lethal dose technique for determining the relative susceptibility of non-target species to 1080 toxin

Calver, M.C., McIlroy, J.C., King, D.R. and Bradley, J.S. (1989) Assessment of an approximate lethal dose technique for determining the relative susceptibility of non-target species to 1080 toxin. Australian Wildlife Research, 16 (1). pp. 33-40.

Abstract

The susceptibility of 8 species of dasyurid marsupials and 5 species of murid rodents from the pastoral areas of Western Australia to the toxin sodium monofluoracetate (Compound 1080) was assessed. Results ranged from a low approximate lethal dose (ALD) of 1.6 mg kg-1 for an island population of Pseudomys hermannsburgensis to a high of 20 mg kg-1 for a mainland population of Notomys mitchelli. Interspecific and regional variation in sensitivity was evident: 3 populations of P. hermannsburgensis showed widely different ALDs, and high ALDs were found in the Millstream area relative to elsewhere in the pastoral regions. Where both ALD and LD50 were available, the dose response curve was steep; All LD50s were less than a factor of 1.5 above the ALD. LD50 values amd ALDs were significantly correlated for selected dasyurids and murids.