New ways to identify novel bacterial antigens for vaccine development
Movahedi, A.R. and Hampson, D.J. (2008) New ways to identify novel bacterial antigens for vaccine development. Veterinary Microbiology, 131 (1-2). pp. 1-13.
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This article provides an overview of developments in approaches to identify novel bacterial components for use in recombinant subunit vaccines. In particular it describes the processes involved in "reverse vaccinology", and some associated complementary technologies such as proteomics that can be used in the identification of new and potentially useful vaccine antigens. Results obtained from the application of these new methods are forming a basis for a new generation of vaccines for use in the control of bacterial infections of humans and animals.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Veterinary and Biomedical Sciences|
|Copyright:||2008 Elsevier BV|
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