Worm control and anthelmintic resistance: adventures with a model

Barnes, E.H., Dobson, R.J. and Barger, I.A. (1995) Worm control and anthelmintic resistance: adventures with a model. Parasitology Today, 11 (2). pp. 56-63.

Abstract

There are three common questions asked of parasitologists about anthelmintic resistance. Does it matter? How do you prevent it? Can you help me (it's here!)? In short, the respective answers are yes, read on and read on. Elizabeth Barnes, Robert Dobson and Ian Barger examine these issues in the context of nematode parasite control in grazing sheep. With the aid of a model, they examine some important factors that influence drug resistance and how farm management decisions and worm genetics modify these factors. They also explore the likely impact of new technologies on drug resistance and how efficient they need to be to sustain good worm control.