Solubility equilibria in the uric acid–sodium urate–water system

Wang, Z. and Königsberger, E. (1998) Solubility equilibria in the uric acid–sodium urate–water system. Thermochimica Acta, 310 (1-2). pp. 237-242.

Abstract

In a constant ionic medium, corresponding to a physiological environment (Ic=0.15moldm-3 NaCl), the solubilities of anhydrous uric acid, uric acid dihydrate and monosodium urate monohydrate have been measured as a function of p[H]=-log[H+](2-8) and temperature (25o, 32o, 37o and 42oC). The solubility equilibria in the uric acid-sodium urate-water system are discussed on the basis of the solubility constants (Ks) and the first dissociation constant (K1) of uric acid and the solubility product (Ks0) of monosodium urate. The quantities measured in this work are in good agreement with literature values, however, the present solubility data have a much higher precision.