The production of a human monoclonal antibody defining a split of HLA-DRw13 (DRw13b)
Bunce, M., Sutton, P.M., Ting, A. and Morris., P.J. (1990) The production of a human monoclonal antibody defining a split of HLA-DRw13 (DRw13b). Tissue Antigens, 36 (3). pp. 100-102.
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By use of the heterohybridoma technique we have produced a human monoclonal antibody (NDS40) which detects a split of HLA-DRwl 3 (DRwl3b) which is in linkage with HLA-DQwl. In addition, the antibody reacts with cells positive for HLA-DRw8 and DRwl 1, but does not react with the commonly found split of DRw1 3 (DRw1 3a) which is associated with DQwl. NDS40 is cytotoxic and is of the lambda IgM class.
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