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Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

Gregg, K., Hamdorf, B., Henderson, K., Kopecny, J. and Wong, C.M. (1998) Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning. Applied and Environmental Microbiology, 64 (9). pp. 3496-3498.

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    Abstract

    Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10(6) to 10(7) cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

    Publication Type: Journal Article
    Murdoch Affiliation: Western Australian State Agricultural Biotechnology Centre
    Publisher: American Society for Microbiology
    Copyright: 1998 American Society for Microbiology
    URI: http://researchrepository.murdoch.edu.au/id/eprint/5648
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