Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning
Gregg, K., Hamdorf, B., Henderson, K., Kopecny, J. and Wong, C.M. (1998) Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning. Applied and Environmental Microbiology, 64 (9). pp. 3496-3498.
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Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10(6) to 10(7) cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||Western Australian State Agricultural Biotechnology Centre|
|Publisher:||American Society for Microbiology|
|Copyright:||1998 American Society for Microbiology|
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