Identification of a new allele in a Sicilian individual: HLA-DPB1*0302

Sheldon, M.H., Azzaro, M.P., Sayer, D., Bunce, M. and Sortino, G. (2005) Identification of a new allele in a Sicilian individual: HLA-DPB1*0302. Tissue Antigens, 66 (1). pp. 64-66.

Abstract

We report here the identification and characterization of a novel human leucocyte antigen (HLA)-DPB1 allele that was subsequently named HLA-DPB1*0302 by the WHO Nomenclature Committee. HLA-DPB1*0302 was identified in a single Sicilian individual by a combination of sequence-specific primers, reverse line sequence-specific oligonucleotide probing and DNA sequencing-based typing. The DPB1*0302 allele is most similar to the DPB1*3101 allele, differing by a single mismatch at nucleotide position 301 (T to G).