Catalog Home Page

Mobile DNA and the TE-Thrust Hypothesis: Supporting Evidence from the Primates

Oliver, K.R. and Greene, W.K. (2011) Mobile DNA and the TE-Thrust Hypothesis: Supporting Evidence from the Primates. Mobile DNA, 2 (1). p. 8.

[img]
Preview
PDF - Published Version
Download (650kB) | Preview
    Link to Published Version: http://dx.doi.org/10.1186/1759-8753-2-8
    *Open access, no subscription required

    Abstract

    Transposable elements (TEs) are increasingly being recognized as powerful facilitators of evolution. We propose the TE-Thrust hypothesis to encompass TE-facilitated processes by which genomes self-engineer coding, regulatory, karyotypic or other genetic changes. Although TEs are occasionally harmful to some individuals, genomic dynamism caused by TEs can be very beneficial to lineages. This can result in differential survival and differential fecundity of lineages. Lineages with an abundant and suitable repertoire of TEs have enhanced evolutionary potential and, if all else is equal, tend to be fecund, resulting in species-rich adaptive radiations, and/or they tend to undergo major evolutionary transitions. Many other mechanisms of genomic change are also important in evolution, and whether the evolutionary potential of TE-Thrust is realized is heavily dependent on environmental and ecological factors. The large contribution of TEs to evolutionary innovation is particularly well documented in the primate lineage. In this paper, we review numerous cases of beneficial TE-caused modifications to the genomes of higher primates, which strongly support our TE-Thrust hypothesis.

    Publication Type: Journal Article
    Murdoch Affiliation: School of Biological Sciences and Biotechnology
    School of Veterinary and Biomedical Sciences
    Publisher: BioMed Central
    Copyright: © 2011 Oliver and Greene
    Notes: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    URI: http://researchrepository.murdoch.edu.au/id/eprint/4626
    Item Control Page

    Downloads

    Downloads per month over past year