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Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef

Williamson, J.F., Steele, E.J., Lester, S., Kalai, O., Millman, J.A., Wolrige, L., Bayard, D., McLure, C. and Dawkins, R.L. (2011) Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef. Genomics, 97 (5). pp. 304-312.

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    Link to Published Version: http://dx.doi.org/10.1016/j.ygeno.2011.02.006
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    Abstract

    We have identified numerous Ancestral Haplotypes encoding a 14-Mb region of Bota C19. Three are frequent in Simmental, Angus and Wagyu and have been conserved since common progenitor populations. Others are more relevant to the differences between these 3 breeds including fat content and distribution in muscle. SREBF1 and Growth Hormone, which have been implicated in the production of healthy beef, are included within these haplotypes. However, we conclude that alleles at these 2 loci are less important than other sequences within the haplotypes. Identification of breeds and hybrids is improved by using haplotypes rather than individual alleles.

    Publication Type: Journal Article
    Murdoch Affiliation: School of Veterinary and Biomedical Sciences
    Publisher: Academic Press
    Copyright: © 2010 Elsevier Inc.
    URI: http://researchrepository.murdoch.edu.au/id/eprint/4405
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