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Structural and evolutionary analysis of an orangutan foamy virus

Verschoor, E.J., Langenhuijzen, S., van den Engel, S., Niphuis, H., Warren, K.S. and Heeney, J.L. (2003) Structural and evolutionary analysis of an orangutan foamy virus. Journal of Virology, 77 (15). pp. 8584-8587.

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    The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.

    Publication Type: Journal Article
    Murdoch Affiliation: School of Veterinary and Biomedical Sciences
    Publisher: American Society for Microbiology
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