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Synthesis of 2‐Acetyl‐4‐hydroxynaphtho[2,3‐b]pyran‐5,10‐dione and the 4‐Deoxy analogue as models for comparative biological evaluations

Ameer, F., Giles, R.G.F., Green, I.R., Hugo, V.I., Patel, Samir and Pearce, René (2004) Synthesis of 2‐Acetyl‐4‐hydroxynaphtho[2,3‐b]pyran‐5,10‐dione and the 4‐Deoxy analogue as models for comparative biological evaluations. Synthetic Communications, 34 (14). pp. 2565-2573.

Link to Published Version: http://dx.doi.org/10.1081/SCC-200025612
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Abstract

Two deoxy analogues of the known antibiotic, erythrostominone, have been synthesised for comparative evaluations. It was found that both the 2‐acetyl and the 4‐hydroxy substituents in the pyran ring are vital for improved biological activity.

Publication Type: Journal Article
Murdoch Affiliation: School of Engineering and Energy
Publisher: Taylor and Francis
URI: http://researchrepository.murdoch.edu.au/id/eprint/32986
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