Tolerance to, and metabolism of, fluoroacetate in the Emu
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Compared with most other birds, the emu, Dromaius novaehollandiae Vieillot, has unusually high tolerance to fluoroacetate (1080). The LD5o for emus with evolutionary exposure to fluoroacetate- bearing vegetation in the south-west of Western Australia was 102 mg of 1080 per kilogram. This tolerance appears to result from: the substantial capacity of emus to detoxify fluoroacetate by defluorination; the limited conversion of fluoroacetate into fluorocitrate by emus; and/or their possession of an aconitate hydratase which is relatively insensitive to fluorocitrate.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Environmental and Life Sciences|
|Copyright:||© 1988, CSIRO.|
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