Catalog Home Page

Recovery of viral agents from the central nervous system of cats

Wilcox, G.E., Flower, R.L. and Cook, R.D. (1984) Recovery of viral agents from the central nervous system of cats. Veterinary Microbiology, 9 (4). pp. 355-66.

Link to Published Version: http://dx.doi.org/10.1016/0378-1135(84)90004-X
*Subscription may be required

Abstract

Isolation of viruses from the central nervous system (CNS) of cats was attempted using an explant culture technique and subsequent co-cultivation with Crandell feline kidney (CRFK) or Vero cells. Feline syncytia-forming virus was isolated from the CNS of 11 of 16 cats where the initial co-cultivation was with CRFK cells. Feline panleucopaenia virus was isolated from the CNS of 2 adult cats. Co-cultured cells from the CNS of 3 cats contained eosinophilic cytoplasmic and intranuclear inclusions. The cytoplasmic inclusions consisted of tubular structures, 16-18 nm in diameter and up to 500 nm in length, which were similar in morphology to paramyxovirus nucleocapsids. The 3 co-cultured cells with cytoplasmic and intranuclear inclusions showed haemadsorption of guinea pig erythrocytes. The possible identity of these structures, and their association with a previously described primary focal demyelinating lesion in the CNS of cats, is discussed.

Publication Type: Journal Article
Murdoch Affiliation: School of Veterinary Studies
Publisher: Elsevier BV
URI: http://researchrepository.murdoch.edu.au/id/eprint/21181
Item Control Page Item Control Page