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Fat metabolism and turnover

Pethick, D.W., Harper, G.S. and Dunshea, F.R. (2005) Fat metabolism and turnover. In: Dijkstra, J. and Forbes, J.M., (eds.) Quantitative Aspects of Ruminant Digestion and Metabolism. CAB International, Wallingford, Oxon, pp. 345-371.

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This chapter will emphasize the metabolism of non-esterified fatty acids (NEFA) although some discussion will relate to triglyceride (TAG) and ketone bodies. Plasma NEFA are a highly labile form of Lipid that are transported between tissues in the circulation bound to albumin. Although plasma NEFA are only a small proportion (5%) of total plasma lipid they represent an important source of oxidizable energy, particularly during periods of negative energy balance or when there is an acute need for energy such as during exercise. This chapter will deal with the composition and sources of plasma NEFA, the fate of NEFA during different physiological states as well as the acute and chronic regulation of NEFA metabolism. In addition, this chapter will cover methodology and principles of NEFA metabolism and also describe adaptations to different physiological states. Although these areas have been covered in several reviews (Lindsay, 1975; Emery, 1979; Annison. 1984; Wiseman. 1984; Chilliard et al., 2000), this chapter will emphasize the quantitative aspects of NEFA metabolism.

Publication Type: Book Chapter
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Publisher: CAB International
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