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Effect of tryptophan depletion on symptoms of motion sickness in migraineurs

Drummond, P.D. (2005) Effect of tryptophan depletion on symptoms of motion sickness in migraineurs. Neurology, 65 (4). pp. 620-622.

Link to Published Version: http://dx.doi.org/10.1212/01.wnl.0000172339.15577....
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Abstract

Seven hours after 39 migraineurs and 37 controls consumed an amino acid drink that contained or omitted l-tryptophan (thereby reducing brain serotonin synthesis), motion sickness was provoked by the visual illusion of movement. Tryptophan depletion boosted dizziness, nausea, and the illusion of movement in controls to levels that approached those of migraineurs. Thus, reduced brain serotonin activity may promote vestibuloocular disturbances during motion sickness and attacks of migraine.

Publication Type: Journal Article
Murdoch Affiliation: School of Psychology
Publisher: Lippincott Williams & Wilkins
Copyright: © 2005 American Academy of Neurology
URI: http://researchrepository.murdoch.edu.au/id/eprint/2000
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