Light and electron microscopy findings in subcutaneous fat antiretroviral treated and HIV-infected patients
Mallal, S., Nolan, D., John, M., Chong, D., Metcalf, C. and Latham, B. (2000) Light and electron microscopy findings in subcutaneous fat antiretroviral treated and HIV-infected patients. In: XIII International AIDS Conference, 9 - 14 July 2000, Durban, South Africa.
This is a small study looking at biopsies of fat cells from 3 NRTI+PI treated individuals and 1 NRTI-treated but PI-naÔve individual with fat loss and accumulation. The biopsies were examined by electron and light microcscopy. The authors found abnormalities which are described below. It's important to bear in mind that this is a very small study limiting conclusions. The author concludes that NRTI treatment alone can lead to the abnormalities found, and the addition of PI treatment may increase abnormalities...
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