In silico prediction of tick vaccine candidates
Kurscheid, S., Rodriguez-Valle, M., Moolhuijzen, P.M., Barrero, R., Guerrero, F.D., Lew-Tabor, A.E. and Bellgard, M.I. (2008) In silico prediction of tick vaccine candidates. In: ASP & ARC/NHMRC Research Network for Parasitology Annual Conference, 6 - 9 July 2008, Glenelg, S.A..
The control of Rhipicephalus (Boophilus) microplus infestations and costs incurred through productions losses amount to $175m per annum for the Australian beef industry and an estimated US$2.5 billion dollars worldwide. A new vaccine for the prevention and control of infestations has been identified as a high research priority. Here we present results of our reverse vaccinology approach that has been used to identify potential vaccine candidates through a combination of an in silico analysis and gene expression studies by quantitative real-time PCR (qPCR).
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|Murdoch Affiliation:||Centre for Comparative Genomics|
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