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Dietary manipulation of infectious bowel disease

Hopwood, D., Pluske, J.R. and Hampson, D.J. (2006) Dietary manipulation of infectious bowel disease. In: Mosenthin, R., Zentek, J. and Żebrowska, T., (eds.) Biology of Nutrition in Growing Animals. Elsevier, Edinburgh , pp. 365-385.

Link to Published Version: http://dx.doi.org/10.1016/S1877-1823(09)70099-2
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Abstract

The chapter presents a discussion on dietary manipulation of infectious bowel disease. This chapter discusses some influences of diet on this system, and provides examples of how manipulation of the diet can help to influence colonization by certain potential enteric pathogens. Examples are drawn mainly from the problems of postweaning diarrhea in the pig, because this is an important condition that exemplifies some of the principles being explored in nutritional intervention of enteric infections. There is general agreement that diet can have an influence on intestinal disease, particularly in young animals. This chapter discusses some such dietary interactions, and particularly focuses on the problem of diarrhea in recently weaned pigs, as this condition has been extensively studied. The pathogenic bacterial species that colonize the intestinal tract, including zoonotic bacteria such as Salmonella and Campylobacter are also discussed in the chapter. Even within an animal species, such as the pig, sites of infection with different pathogens vary from the stomach (for example, Helicobacter species), small intestine (for example, Escherichia coli) to the colon (for example, Brachyspira species). Postweaning diarrhea (PWD) is a common disease that occurs in piggeries throughout the world. Piglets usually develop a watery diarrhea, and show a rapid loss of condition, with most members of a litter being affected. The most common and significant pathogenic types associated with PWD are enterotoxigenic E. coli (ETEC). Brachyspira pilosicoli is an anaerobic spirochete that colonizes the large intestine of pigs, as well as a variety of bird species, dogs and human beings.

Publication Type: Book Chapter
Murdoch Affiliation: Animal Research Institute
School of Veterinary and Biomedical Sciences
Publisher: Elsevier
Copyright: © 2006 Elsevier Ltd.
URI: http://researchrepository.murdoch.edu.au/id/eprint/11300
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