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Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion

Keane, N., Almeida, C., Chopra, A., Cooper, D., Demaine, E., Mallal, S. and John, M. (2012) Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion. Retrovirology, 9 (Suppl 2).

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    Abstract

    Identification of the earliest CD8 T-cell responses against HIV may help select critical viral targets for inclusion in an HIV vaccine. We describe changes to the earliest detected CD8 T-cell responses and changes in genetic sequence encoding targeted epitopes in an individual who presented with Fiebig stage II, clade C acute HIV-infection, 27 days after sexual transmission.

    Publication Type: Journal Article
    Murdoch Affiliation: Institute for Immunology and Infectious Diseases
    Publisher: BioMed Central
    Copyright: © 2012 Keane et al
    Notes: Poster Presentation at AIDS Vaccine 2012, Boston, 9-12 September, 2012.
    URI: http://researchrepository.murdoch.edu.au/id/eprint/10924
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