Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion
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Keane, N., Almeida, C., Chopra, A., Cooper, D., Demaine, E., Mallal, S. and John, M. (2012) Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion. Retrovirology, 9 (Suppl 2).
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Abstract
Identification of the earliest CD8 T-cell responses against HIV may help select critical viral targets for inclusion in an HIV vaccine. We describe changes to the earliest detected CD8 T-cell responses and changes in genetic sequence encoding targeted epitopes in an individual who presented with Fiebig stage II, clade C acute HIV-infection, 27 days after sexual transmission.
| Publication Type: | Journal Article |
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| Murdoch Affiliation: | Institute for Immunology and Infectious Diseases |
| Publisher: | BioMed Central |
| Copyright: | © 2012 Keane et al |
| Notes: | Poster Presentation at AIDS Vaccine 2012, Boston, 9-12 September, 2012. |
| URI: | http://researchrepository.murdoch.edu.au/id/eprint/10924 |
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