Biochemical characterisation of Australian strains of Echinococcus granulosus by isoelectric focusing of soluble proteins

Kumaratilake, L.M. and Thompson, R.C.A. (1984) Biochemical characterisation of Australian strains of Echinococcus granulosus by isoelectric focusing of soluble proteins. International Journal for Parasitology, 14 (6). pp. 581-586.

Abstract

The existence of three distinct strains of E. granulosus in Australia has been previously demonstrated on the basis of several criteria. In the present study, numerous isolates of E. granulosus from domestic and wild animal populations in different geographical areas of Australia were subjected to detailed biochemical analysis using isoelectric focusing of soluble proteins. Three different populations were recognised which corresponded to the three strains described previously, thus confirming their genetic distinction. One strain is common to all domestic intermediate hosts on the Australian mainland. Evidence is presented that humans and macropod marsupials are also susceptible to infection with this strain and that it is similar to E. granulosus occurring in sheep in New Zealand and the United Kingdom. The other two strains are confined to macropod marsupials on the Australian mainland and sheep in Tasmania respectively.