Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole
Meloni, B.P., Thompson, R.C.A., Reynoldson, J.A. and Seville, P. (1990) Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84 (3). pp. 375-379.
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The effects of albendazole were assessed against Giardia duodenalis in vitro and compared with those of tinidazole and metronidazole. Trophozoite morphology, adherence and viability were markedly affected by albendazole, to a far greater extent than by either metronidazole or tinidazole. The results of this study, and in particular the superior potency of albendazole in vitro, are discussed with respect to its potential value as a new approach to the chemotherapy of giardiasis.
|Publication Type:||Journal Article|
|Murdoch Affiliation:||School of Veterinary Studies|
|Publisher:||Royal Society of Tropical Medicine and Hygiene|
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